Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC [Phase 1]
Phase 1 dose-escalation study of L-DOS47 in patients with recurrent or metastatic non-squamous non-small cell lung cancer was terminated; re…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases [Phase 2]
This randomized Phase II trial evaluates osimertinib with or without stereotactic radiosurgery (SRS) in patients with EGFR-mutant non-small …
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK [Phase 2]
Phase 2 clinical trial update for ALK-rearranged non-small cell lung cancer evaluating pembrolizumab plus bevacizumab and chemotherapy, with…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of LMV-12 with Osimertinib for non-small cell lung cancer, including tumors with RE…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Evaluate the Mediators of Sensitivity and Resistance to Nivolumab Plus Ipilimumab in Patients With Advanced NSCLCs [Phase 2]
Phase 2 trial evaluating biomarkers of sensitivity and resistance to nivolumab plus ipilimumab in advanced non-small cell lung cancer, with …
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions [Phase 3]
Phase 3 trial evaluating amivantamab with carboplatin-pemetrexed versus carboplatin-pemetrexed alone in advanced/metastatic non-small cell l…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Pulmonary sarcomatoid_MEDI4736+Treme [Phase 2]
A Phase 2 trial evaluating the combination of durvalumab and tremelimumab for pulmonary sarcomatoid carcinoma and non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions [Phase 3]
Phase 3 trial comparing amivantamab plus carboplatin-pemetrexed versus carboplatin-pemetrexed in advanced/metastatic non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies [Phase 1]
This Phase 1 trial evaluated the safety and tolerability of immunotherapy combinations across multiple advanced cancers and has completed.
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Registry to Evaluate the Performance of the BDX-XL2 Test
This document reports a completed clinical trial registry evaluating the performance of the BDX-XL2 diagnostic test.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: L-TIL Plus Tislelizumab for PD1 Antibody Resistant aNSCLC [Phase 2]
A Phase 2 trial evaluates L-TIL plus tislelizumab for PD-1 antibody–resistant advanced non-small cell lung cancer. The study is currently re…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Study of PD-1 Inhibitor JTX-4014 Alone and in Combination With Vopratelimab in Biomarker-selected Subjects With Metastatic NSCLC After One Prior Platinum-containing Regimen [Phase 2]
A Phase 2 study evaluating JTX-4014 alone and in combination with vopratelimab in biomarker-selected metastatic non-small cell lung cancer a…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: 99mTc/68Ga Labeled Anti-PD-L1 sdAb in Assessment of PD-L1 Expression in NSCLC [EARLY_Phase 1]
An early Phase 1 study evaluated a radiolabeled anti-PD-L1 single-domain antibody (99mTc/68Ga-labeled) for imaging PD-L1 expression in non-s…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86) [Phase 3]
Phase 3 trial comparing subcutaneous pembrolizumab versus intravenous pembrolizumab with platinum doublet chemotherapy in metastatic non-sma…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Atezolizumab With Stereotactic Ablative Radiotherapy in Patients With Metastatic Tumours [Phase 2]
Phase 2 clinical trial evaluating atezolizumab in combination with stereotactic ablative radiotherapy for metastatic colorectal cancer, non-…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Relation Between Tumor-draining Lymph Nodes Metastasis Pattern and Non-small Cell Lung Cancer Neoadjuvant Immunotherapy Effectiveness
A completed clinical trial evaluated how patterns of tumor-draining lymph node metastasis relate to the effectiveness of neoadjuvant immunot…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Real-Life Study With Nivolumab (BMS-936558) in Advanced NSCLC Patients After Prior Chemotherapy
Completed real-world study evaluating nivolumab in adults with advanced non-small cell lung cancer after prior chemotherapy.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 study of GSK3901961 in previously treated synovial sarcoma, myxoid/round cell liposarcoma, and metastatic non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Exploring the Theragnostic Value of Osimertinib in EGFR-mutated Lung Cancer (THEROS) [Phase 2]
Phase 2 trial update evaluating the theragnostic value of osimertinib in epidermal growth factor receptor-mutated non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment [Phase 1, Phase 2]
Completed Phase 1/2 trial evaluating the combination of rigosertib and nivolumab in KRAS-positive non-small cell lung cancer patients who pr…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of carfilzomib with irinotecan in irinotecan-sensitive cancers and small cell lung cancer has com…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Shenlingcao Oral Liquid for Patients With Stage II or IIIA NSCLC [Phase 4]
Phase 4 clinical trial update on Shenlingcao Oral Liquid for patients with stage II/IIIa non-small cell lung cancer following chemotherapy. …
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: A Radiomic Model for Risk of Local Recurrence and DFS for T3 and T4 Non-small Cell Lung Cancer
A completed clinical trial evaluates a radiomic model to predict local recurrence risk and disease-free survival in patients with T3-T4 non-…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas [Phase 1, Phase 2]
This clinical trial update reports the completion and posted results of a Phase 1/2 study evaluating TRC102 in combination with Temozolomide…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the combination of cisplatin, docetaxel, and nintedanib given before surgery in patients with previously untreated …