Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Efficacy and Safety of Concurrent Chemoradiotherapy With Oral Vinorelbine in Patients With Non-small Cell Lung Cancer [Phase 2]
This Phase 2 trial update evaluates the efficacy and safety of concurrent chemoradiotherapy using oral vinorelbine in patients with non-smal…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC. [Phase 2]
Phase 2 trial evaluating chidamide in combination with envafolimab for PD-1 inhibitor-resistant advanced non-small cell lung cancer has comp…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer [Phase 1]
An open-label Phase 1 study evaluates ONO-4578 and ONO-4538 in combination with standard-of-care docetaxel and ramucirumab as second-line th…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration [Phase 2]
A Phase 2 study evaluated the efficacy and safety of pemigatinib in participants with relapsed or refractory advanced non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2) [Phase 3]
Phase 3 trial FLAURA2 compares osimertinib with or without chemotherapy as first-line treatment for EGFR-mutated non-small cell lung cancer;…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants [Phase 1, Phase 2]
Phase 1/2 study evaluating ASP0739 alone and in combination with pembrolizumab in NY-ESO-1 expressing advanced solid tumors was terminated, …
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Food Reward in Cachexia Induced by Acute or Chronic Disease
The clinical trial evaluating food reward as a treatment for cachexia across acute or chronic diseases has been terminated; the conditions i…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib [Phase 1, Phase 2]
A completed Phase 1/Phase 2 study evaluating AT13387 in non-small cell lung cancer, both as monotherapy and in combination with crizotinib. …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Study of Cisplatin + Pemetrexed + Avastin as First-Line Therapy [Phase 2]
Phase 2 study of cisplatin plus pemetrexed and bevacizumab as first-line therapy for non-small cell lung cancer has been terminated with res…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors [Phase 2]
A Phase 2 trial evaluating Cediranib in combination with Olaparib in advanced solid tumors has posted results as of 2024-07-30. Indications …
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: First-in-Human Phase I/II Study of FHND-9041 in Patients With EGFR Mutated Advanced Non-Small Cell Lung Cancer [Phase 1, Phase 2]
First-in-human Phase I/II study of FHND-9041 in patients with EGFR-mutated advanced non-small cell lung cancer has been completed.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b [Phase 1]
XMT-1536, an investigational NaPi2b-targeting agent from Mersana Therapeutics, completed a first-in-human Phase 1 dose-escalation study in c…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: First-in-Human Dose Expansion Study of XMT-1536 in Cancers Likely to Express NaPi2b [Phase 1]
First-in-human dose expansion Phase 1 trial of XMT-1536 targeting NaPi2b in cancers likely to express the transporter, including platinum-re…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: A Study of NBF-006 in Non-Small Cell Lung, Pancreatic, or Colorectal Cancer [Phase 1]
NBF-006's Phase 1 trial in non-small cell lung cancer, pancreatic cancer, and colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Omitting of Lymphadenectomy is Acceptable for Lung Cancer Smaller Than 6 mm in Solid Size
The completed trial evaluated whether omitting lymphadenectomy is feasible and safe for very small non-small cell lung cancers with solid si…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Evaluation of a Novel Microfluidic Device to Purify Metastatic Lung Cancer Patients CTC (Circulating Tumoral Cells)
A terminated clinical trial evaluating a novel microfluidic device to purify circulating tumor cells in patients with metastatic non-small c…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing neoadjuvant chemotherapy plus nivolumab versus chemotherapy plus placebo, followed by surgery and adjuvant therapy, …
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: A Multi-Centre, Prospective, Non-Interventional Study to Intensively Monitor the Safety of Osimertinib in Clinical Practice Among Chinese NSCLC Patients
This is a multi-centre, prospective, non-interventional study that intensively monitors the safety of osimertinib in Chinese patients with n…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151) [Phase 3]
Phase 3 IMpower151 trial evaluating bevacizumab with chemotherapy, with or without atezolizumab, in chemo-naïve stage IV non-squamous non-sm…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors [Phase 1, Phase 2]
Phase 1/2 study of HH2710 in patients with melanoma and other advanced tumors was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Neoadjuvant Aliya™ PEF Soft Tissue Ablation With Systemic Therapy in Early-Stage Resectable NSCLC [Phase 4]
Phase 4 neoadjuvant trial of Aliya PEF Soft Tissue Ablation with systemic therapy in early-stage resectable non-small cell lung cancer has b…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Feasibility Study of the Aliya System in the Treatment of Early Stage Non-small Cell Lung Cancer [NA]
This clinical trial update reports the completion of a feasibility study evaluating the Aliya System for early-stage non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Second-Line Nivolumab Monotherapy in Asia [Phase 3]
A Phase 3 clinical trial in Asia assessing second-line nivolumab monotherapy for non-small cell lung cancer has completed and posted results…