Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Study Of Comparing SAF-189s With Crizotinib In First Line ALK-Positive Advanced and Metastatic NSCLC [Phase 3]
A Phase 3 trial compares SAF-189s to Crizotinib as first-line therapy for ALK-positive advanced/metastatic non-small cell lung cancer; the s…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Vaccine-Based Immunotherapy Regimen For NSCLC and TNBC [Phase 1]
Pfizer's Phase 1 trial of a vaccine-based immunotherapy regimen for non-small cell lung cancer and triple-negative breast cancer was termina…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008) [Phase 3]
Phase 3 trial evaluating pembrolizumab plus lenvatinib versus docetaxel in metastatic non-small cell lung cancer after platinum doublet chem…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors [Phase 1, Phase 2]
Cantargia AB's CAN04 first-in-human study in solid malignant tumors (Phase 1/2) has completed. The trial encompassed several indications, in…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer [Phase 1]
Phase 1 trial evaluating sirolimus in combination with durvalumab for stage I–IIIA non-small cell lung cancer. The study is terminated with …
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Biomarkers of Response to Ipilimumab and Nivolumab in First-line NSCLC [Phase 2]
Phase 2 trial evaluating biomarkers of response to the combination of ipilimumab and nivolumab as first-line therapy for non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Osimertinib and Navitoclax in Treating Patients With EGFR-Positive Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer [Phase 1]
This is a Phase 1 clinical trial update evaluating the combination of osimertinib and navitoclax in patients with EGFR-positive, previously …
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer [Phase 1]
Phase 1 trial update evaluating AZD9150 alone or with durvalumab, with or without chemotherapy, in patients with advanced solid tumors and n…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of everolimus and vatalanib in patients with advanced solid tumors, including several neuroendocrin…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Efficacy and Safety Study of DURVALUMAB Maintenance in Patients With Stage III Non-Small Cell Lung Cancer
Clinical trial update describing a maintenance therapy study with durvalumab in stage III non-small cell lung cancer, focusing on efficacy a…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: The Study of Tusamitamab Ravtansine (IBI126) Combined With Sintilimab and Tusamitamab Ravtansine (IBI126) Combined With Sintilimab Plus Platinum-based Chemotherapy and Pemetrexed in Subjects With CEACAM5 Positive Expression Advanced/Metastatic Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC) [Phase 2]
A Phase 2 study evaluating Tusamitamab Ravtansine (IBI126) with Sintilimab, with or without platinum-based chemotherapy and pemetrexed, in C…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors [Phase 1, Phase 2]
This update reports the termination of a Phase 1/2 trial of AMG 655 in combination with AMG 479 for advanced, refractory solid tumors, with …
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: SRT for Residual Oligometastases of NSCLC After 3rd Generation EGFR-TKIs [Phase 2]
Phase 2 clinical trial evaluating stereotactic radiotherapy (SRT) for residual oligometastases in non-small cell lung cancer after third-gen…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: The Impact of Probiotic on Survival and Treatment Response in Metastatic Non-small Cell Lung Cancer Patients [NA]
This clinical trial update investigates whether probiotic supplementation affects survival and treatment response in metastatic non-small ce…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Local Recurrence Prediction of by Texture Analysis Derived From Positron Emission Tomography (PET / CT) Imaging of Non-small Cell Lung Cancer (NSCLC) Treated With Stereotactic Radiotherapy (SBRT) (Retros MUMOFRAT)
A retrospective analysis investigates whether texture features from FDG PET/CT can predict local control in non-small cell lung cancer treat…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002) [Phase 2]
Phase 2 study MK-2140-002 evaluating Zilovertamab vedotin (VLS-101) in solid tumors including triple-negative breast cancer and non-small-ce…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Advanced Lung Tumor Treated by Osimertinib Plus Anlotinib [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of osimertinib and anlotinib for advanced non-small cell lung cancer with EGFR mutations…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging [Phase 2]
Phase 2 trial evaluating FLARE RT personalized radiation therapy for stage IIB-IIIB non-small cell lung cancer using PET/CT and SPECT/CT ima…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017 [Phase 1, Phase 2]
Phase 1/2 study evaluating pembrolizumab with Imprime PGG in metastatic non-small cell lung cancer after progression on first-line therapy; …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Real-world Data on Stage III NSCLC Patients Treated With Durvalumab After Chemoradiotherapy in Asia Area (PACIFIC AA)
Real-world data from a completed clinical trial program examining durvalumab after chemoradiotherapy in Asian stage III non-small cell lung …
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Toripalimab Combined With Double Platinum-based Chemotherapy for Initially Unresectable NSCLC [Phase 2]
Phase 2 trial results on toripalimab combined with double platinum-based chemotherapy for initially unresectable advanced non-small cell lun…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: AST-VAC2 Vaccine in Patients With Non-small Cell Lung Cancer [Phase 1]
Phase 1 results update for AST-VAC2 vaccine in patients with advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: SBRT Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
A phase 1/2 trial evaluating SBRT combined with Avelumab for non-small cell lung cancer was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics, and preliminary efficacy of the oral SM08502 with hormonal therapy or chemotherapy in…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)
This completed clinical trial (IDEALK&ROS) identifies patients with advanced/metastatic non-small cell lung cancer who harbor ALK or ROS1 tr…