Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS3]
A real-world emulation study by Aetion evaluating the KEYNOTE-189 regimen in metastatic non-small cell lung cancer. The study status is COMP…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671) [Phase 3]
Phase 3 MK-3475-671 evaluates pembrolizumab added to platinum-doublet chemotherapy as neoadjuvant/adjuvant therapy for resectable stage II, …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671) [Phase 3]
Phase 3 trial evaluating pembrolizumab with platinum doublet chemotherapy as neoadjuvant/adjuvant therapy for resectable stage II-IIIA and s…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Molecular Profiling Study of Patients With EGFR Mutation-positive Locally Advanced or Metastatic NSCLC Treated With Osimertinib [Phase 2]
Phase 2 molecular profiling study of patients with EGFR mutation-positive locally advanced or metastatic non-small cell lung cancer treated …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: SinTilimab After Radiation (STAR Study) [Phase 2]
Phase 2 STAR trial evaluating SinTilimab after radiation for non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Trial Evaluating Stereotactic Radiotherapy Plus Durvalumab Continuation for Patients With NSCLC Metachronous Oligometastatic Disease Under Durvalumab Consolidation Following Chemoradiation [Phase 2]
A Phase 2 clinical trial evaluating continuation of durvalumab with added stereotactic radiotherapy for non-small cell lung cancer patients …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: JAB-3068 Activity in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial update for JAB-3068 in adults with advanced solid tumors, including Esophageal Squamous Cell Carcinoma, No…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Radiotherapy to the Primary in Metastatic Non-small Cell Lung Cancer Patients [Phase 3]
A Phase 3 trial evaluating radiotherapy to the primary tumor in metastatic non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Anaplastic Lymphoma Kinase (ALK)-Positive Non-small Cell Lung Cancer (NSCLC) Post-alectinib Treatment Patterns
Pfizer's completed trial evaluates post-alectinib treatment patterns in ALK-positive non-small cell lung cancer. The study results have been…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: PH009-1 in Patients With EGFR Mutation Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
PH009-1 is an investigational therapy for EGFR-mutated non-small cell lung cancer (locally advanced or metastatic), and the Phase 1/2 trial …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant Cancer [Phase 1]
The trial update indicates termination of the Phase 1b/2 study of futibatinib in combination with binimetinib for advanced KRAS-mutant cance…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation [Phase 2]
Phase 2 trial evaluating ensartinib in combination with bevacizumab in ALK-positive non-small cell lung cancer patients with TP53 mutation i…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Effects of an Nutritional Intervention on PD-1 ICI in NSCLC [NA]
A completed clinical trial evaluating the effects of a nutritional intervention on PD-1 immune checkpoint inhibitor therapy in non-small cel…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS4]
Aetion's CARE Initiative reports completion of a real-world emulation study based on the KEYNOTE-189 trial in metastatic non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Clinical Trial of TQB2928 in Combination With a Third-Generation Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) in Patients With Advanced Non-Small Cell Lung Cancers [Phase 1]
A Phase 1 trial is evaluating TQB2928 in combination with a third-generation EGFR tyrosine kinase inhibitor for advanced non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Icotinib Following Chemotherapy Versus Chemotherapy as Adjuvant Therapy in Stage IIA-IIIA NSCLC With EGFR Mutation [Phase 3]
Phase 3 trial comparing icotinib after chemotherapy versus chemotherapy alone as adjuvant therapy in stage IIA-IIIA non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: ctDNA Dynamic Monitoring and Its Role of Prognosis in Stage I NSCLS by NGS
This clinical trial update reports on using dynamic monitoring of circulating tumor DNA (ctDNA) by next-generation sequencing to assess prog…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Pembrolizumab in Elderly Patients With Advanced Lung Cancer [Phase 2]
Phase 2 clinical trial of pembrolizumab in elderly patients with advanced non-small cell lung cancer has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Phase 2 Study of S-1 as 2nd Line Therapy in Advanced Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating S-1 as second-line therapy for advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer [NA]
A pilot study evaluating response-driven adaptive radiation therapy for locally advanced non-small cell lung cancer has completed, with resu…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Phase 2 Study of S-1 in Combination With Cisplatin as 1st Line Therapy in Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of S-1 in combination with cisplatin for first-line treatment of advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Phase III trial evaluating durvalumab in combination with chemotherapy in completely resected stage II-III non-small cell lung cancer comple…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in NSCLC [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of combining Sintilimab with chemotherapy and cryoablation in non-small cell lung …
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC [Phase 2]
Phase 2 clinical trial evaluating high-dose radiation followed by chemotherapy and radiation for locally advanced non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing adjuvant alectinib to adjuvant platinum-based chemotherapy in ALK-positive non-small cell lung cancer; results were …