Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A Study to Evaluate D-1553 in Combination Therapy in Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/2 study evaluating D-1553 in combination therapy for non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Improving Pulmonary Function Following Radiation Therapy [NA]
A completed clinical trial evaluating pulmonary function after radiation therapy in non-small cell lung cancer has posted results.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases [Phase 1]
A Phase 1 study evaluating the safety and mechanism of radium-223 dichloride in combination with pembrolizumab in stage IV non-small cell lu…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of NGM831 as a monotherapy and in combination with pembrolizumab (with or without NGM438) in advanced or metastatic solid tu…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 study comparing the amivantamab and lazertinib combination to osimertinib in locally advanced or metastatic non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing amivantamab plus lazertinib versus osimertinib in locally advanced or metastatic non-small cell lung cancer is activ…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain Metastasis [Phase 2]
Phase 2 trial evaluating atezolizumab with carboplatin and pemetrexed in chemotherapy-naïve patients with asymptomatic brain metastases from…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Pembrolizumab in Patients With Metastatic Non-squamous Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial of pembrolizumab in metastatic non-squamous non-small cell lung cancer has completed, with results posted in October 2024.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC [Phase 2]
A Phase 2 trial evaluating durvalumab as monotherapy or in combination with novel agents for unresectable Stage III non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors [Phase 1, Phase 2]
Phase I/II trial evaluating the safety and preliminary activity of nivolumab combined with vorolanib in patients with refractory thoracic tu…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects [Phase 3]
A Phase 3 trial evaluating pembrolizumab plus platinum-based chemotherapy with or without canakinumab in untreated locally advanced or metas…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)-China Extension Study [Phase 3]
This Phase 3 China-extension trial update reports completion and posting of results for the LEAP-006 study evaluating pemetrexed + platinum …
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Stereotactic Body Radiation Therapy for Inoperable Locally-advanced Non-small Cell Lung Cancer [Phase 1]
This update notes the completion of a Phase 1 trial evaluating stereotactic body radiation therapy for inoperable locally-advanced non-small…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Investigating the Feasibility of a Physical Activity (tele)coaching Intervention in Patients with Non-small Cell Lung Cancer: an Explorative Study [NA]
An exploratory, completed clinical trial assessing the feasibility of a telecoaching physical activity intervention for patients with non-sm…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer
A clinical trial update evaluating the value of the 68Ga-grazytracer PET imaging tracer in guiding immunotherapy for stage III non-small-cel…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Application of Machine Learning Algorithms to Identify Optimal Candidates for Primary Tumor Resection in Patients with Metastatic Non-small Cell Neuroendocrine Tumors
This study update reports completion of a trial applying machine learning to identify metastatic non-small cell lung cancer patients who may…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: A BRIDGING STUDY OF PF-06439535 (CN) PLUS PACLITAXEL-CARBOPLATIN VERSUS BEVACIZUMAB PLUS PACLITAXEL-CARBOPLATIN IN NSCLC [Phase 3]
A Phase 3 bridging study comparing PF-06439535 plus paclitaxel-carboplatin versus bevacizumab plus paclitaxel-carboplatin in advanced non-sm…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours [Phase 1, Phase 2]
A first-in-human Phase 1/2 study evaluating the safety and tolerability of AZD8853 in selected advanced/metastatic solid tumors (urinary bla…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Efficacy and Safety of Combination Therapy With Bojungikki-tang and Pembrolizumab Monotherapy in Patients With Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of combining Bojungikki-tang with pembrolizumab in patients with advanced non-small cell …
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Descriptive Observational Study ALK-2016-CPHG
A descriptive observational study of crizotinib in non-small cell lung cancer with ALK or ROS1 rearrangements has completed, and results wer…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Icotinib for Completed Resected IB NSCLC With EGFR Mutation [Phase 2]
This update reports the completion of a Phase 2 trial of icotinib for resected Stage IB non-small cell lung cancer with EGFR mutation, with …
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Study of Durvalumab Following Radiation Therapy in Patients With Stage 3 Unresectable NSCLC Ineligible for Chemotherapy [Phase 2]
Phase 2 trial results update for durvalumab after radiation therapy in patients with stage 3 unresectable non-small cell lung cancer who are…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China [Phase 1, Phase 2]
First-in-human study of JAB-3068, an SHP2 inhibitor, in adults with advanced solid tumors in China, including non-small cell lung cancer, he…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 bioequivalence study comparing the proposed talazoparib capsule formulation to the current formulation, plus a food-effect assessmen…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC [Phase 2]
This Phase 2 trial in EGFR-mutant, MET-amplified advanced non-small cell lung cancer compares Savolitinib plus Osimertinib versus Savolitini…