Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: --SuPERIOR Trial-- [Phase 2]
Phase 2 clinical trial for Non-Small Cell Lung Cancer was terminated; no results are provided in the update.
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy [Phase 3]
Phase 3 trial comparing patritumab deruxtecan to platinum-based chemotherapy in EGFR-mutant non-small cell lung cancer after EGFR TKI failur…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation [Phase 3]
A Phase 3 trial comparing Capmatinib to Docetaxel in previously treated non-small cell lung cancer with MET exon 14 skipping mutation was te…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study [Phase 2]
Phase II IMMUNOSABR trial testing immunotherapy with stereotactic ablative radiotherapy for stage IV non-small cell lung cancer was terminat…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: The Effect of Nurse Navigation Program on Lung Cancer Patients [NA]
This entry reports the completed clinical trial from Akdeniz University evaluating the effect of a nurse navigation program on patients with…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: A Study to Assess Prevalence of a Specific Protein Overexpression in Adult Participants With Non-Small Cell Lung Cancer
This completed clinical trial assessed the prevalence of overexpression of a specific protein in adults with non-small cell lung cancer. The…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Durvalumab and Low-dose PCI vs Durvalumab and Observation in Radically Treated Patients With Stage III NSCLC (NVALT28) [Phase 3]
Phase 3 trial comparing durvalumab with low-dose prophylactic cranial irradiation (PCI) versus durvalumab with observation in radically trea…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Osimertinib (AZD9291) in First-line Locally Advanced or Metastatic NSCLC Patients With EGFR and EGFR T790M [Phase 2]
This Phase 2 trial evaluated osimertinib as first-line therapy in locally advanced or metastatic non-small cell lung cancer patients with EG…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001) [Phase 1]
Phase 1 study of mRNA-5671/V941 as monotherapy and in combination with pembrolizumab (V941-001) was terminated, with results posted on 2025-…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial update reports results for pembrolizumab with or without standard chemotherapy in adults aged 70 and older with adv…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity
A completed clinical trial evaluating modifiable biomarkers to predict immunotherapy response and toxicity in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors [Phase 2]
A Phase 2 trial evaluating Olaparib plus Durvalumab in EGFR-mutated non-small cell lung cancer that transformed to small cell lung cancer an…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC
This clinical trial update addresses survival outcomes of EGFR-TKI therapy in patients with uncommon EGFR-mutant advanced non-small cell lun…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Switch Maintenance Pembrolizumab in Patients With NSCLC After First Line Platinum Doublet Chemotherapy [Phase 2]
Phase 2 trial evaluating switch maintenance pembrolizumab after first-line platinum doublet chemotherapy in metastatic non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 4]
Phase 4 study evaluating long-term safety and efficacy of atezolizumab (Tecentriq) in previously treated locally advanced or metastatic non-…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK) [Phase 1]
Phase 1 trial evaluating Pfizer's investigational crizotinib (PF-02341066) in ALK-positive non-small cell lung cancer was terminated, with r…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Keynatinib in Treated Patients With NSCLC and Brain Metastases [Phase 2]
Phase 2 trial of Keynatinib in previously treated non-small cell lung cancer with brain metastases has completed; the update does not detail…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation [Phase 3]
Phase 3 trial update comparing adagrasib (MRTX849) to docetaxel in KRAS G12C-mutant non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: A Study of SEA-CD40 Given With Other Drugs in Cancers [Phase 2]
Phase 2 study of SEA-CD40 in combination with other therapies for melanoma and non-small cell lung cancer has completed and results were pos…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating NC-6004 (a cisplatin nanoparticle formulation) in combination with gemcitabine has completed testing i…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation [Phase 3]
Phase 3 study of adagrasib (MRTX849) versus docetaxel in advanced/metastatic KRAS G12C non-small cell lung cancer is active/not recruiting w…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors [Phase 1]
Phase 1 study of ELI-002 in KRAS-mutated pancreatic ductal adenocarcinoma and other KRAS-driven solid tumors has completed enrollment, with …
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2) [Phase 1, Phase 2]
This document is a completed Phase 1/Phase 2 clinical trial update for CAB-ROR2-ADC evaluating safety and efficacy in non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial comparing Sacituzumab Govitecan to Docetaxel in advanced or metastatic non-small cell lung cancer has results posted as of 2…