Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring HER2 Exon 20 Mutations [Phase 3]
Phase 3 trial of poziotinib in previously treated locally advanced or metastatic non-small cell lung cancer with HER2 exon 20 mutations is s…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating immunotherapy or targeted therapy with or without stereotactic radiosurgery for brain metastases from melanoma or…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Randomized, Two-Cohort, Open-Label, Phase 3 Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In [Phase 3]
Phase 3 trial evaluating N-803 plus tislelizumab or prior failed immune checkpoint inhibitor with docetaxel vs docetaxel alone in advanced/m…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Pharmacogenomics IND EXEMPT SNP Clinical Trial - Alectinib and Single Nucleotide Polymorphisms [Phase 2, Phase 3]
Phase 2/3 clinical trial update investigating alectinib in relation to pharmacogenomics SNPs in non-small cell lung cancer. The study is act…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Natural Killer Cells and Bortezomib to Treat Cancer [Phase 1]
This Phase 1 clinical trial update reports on the combination of natural killer cells and bortezomib for several cancers, and the study has …
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment [Phase 2]
Phase 2 clinical trial evaluating safety and preliminary efficacy of Pumitamig (BNT327) in combination with chemotherapy for first-line or s…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Serplulimab Combined With Chemotherapy in Patients With Resectable Non-small-cell Lung Cancer [Phase 2]
A Phase 2 trial update evaluating serplulimab in combination with chemotherapy as neoadjuvant therapy for resectable non-small-cell lung can…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC [Phase 1]
This document reports an ongoing Phase 1 trial evaluating the combination of tepotinib and pembrolizumab for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers [Phase 1]
A Phase I trial evaluating [177Lu]Lu-NNS309, a radiopharmaceutical, in multiple advanced cancers including pancreatic ductal adenocarcinoma,…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating a cancer lysate vaccine with Montanide ISA-51 VG, with or without the IL-15 super-agonist N-80…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating LY3295668 in combination with osimertinib for advanced or metastatic EGFR-mutant non-squamous non-smal…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies [Phase 1]
Pfizer's Phase 1 trial of PF-08046037 alone or with sasanlimab in advanced cancers has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Stereotactic Radiosurgery in Treating Patients Undergoing Chemotherapy and Radiation Therapy For Stage III Non-Small Cell Lung Cancer [NA]
The ClinicalTrials.gov study NCT00945451 investigates the use of stereotactic radiosurgery for patients with stage III non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Patient-Reported Outcomes Following Chemoradiotherapy for Locally Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial results reporting patient-reported outcomes after chemoradiotherapy for locally advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: A Phase 1/2 Study of Anvumetostat in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study evaluating the combination of Anvumetostat with IDE397 in MTAP-null solid tumors has completed, including MTAP-null non-sm…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors [Phase 1]
This first-in-human Phase 1 trial update reports ALX2004 for advanced or metastatic solid tumors and notes that the study is currently recru…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy for Stage III Non-small Cell Lung Cancer [Phase 2]
This entry reports the completion and posted results of a Phase 2 trial evaluating positron emission tomography and computed tomography to g…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: A Phase II Study of Atezolizumab in Combination With Bevacizumab, Carboplatin or Cisplatin, and Pemetrexed for EGFR-mutant Metastatic Non-small Cell Lung Cancer Patients After Failure of EGFR Tyrosine Kinase Inhibitors. [Phase 2]
A Phase II trial evaluating a combination of atezolizumab, bevacizumab, carboplatin or cisplatin, and pemetrexed in patients with EGFR-mutan…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Preoperative Radioimmunotherapy Versus Chemoimmunotherapy in NSCLC [Phase 2]
A Phase 2 clinical trial comparing preoperative radioimmunotherapy versus chemoimmunotherapy for non-small cell lung cancer is currently rec…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: RACE-2L: Real-World Assessment of Clinical Practice and Outcomes in Non-squamous NSCLC After Failure of Platinum-based Chemotherapy in Brazil
Real-world observational trial in Brazil evaluating treatment patterns and outcomes in non-squamous non-small cell lung cancer after platinu…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors [Phase 2]
This Phase 2 trial update evaluates the efficacy and safety of tisotumab vedotin in solid tumors. It includes colorectal cancer, non-small c…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of Tucidinostat Combined With Tislelizumab as First-line Treatment in Advanced NSCLC [Phase 2]
Phase 2 study evaluating tucidinostat in combination with tislelizumab as first-line treatment for advanced Non-Small Cell Lung Cancer has c…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma [Phase 1]
Phase 1 study of atezolizumab in combination with epacadostat in previously treated non-small cell lung cancer and urothelial cancer; the tr…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial comparing Divarasib to Sotorasib or Adagrasib in previously treated KRAS G12C-positive advanced or metastatic non-s…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Phase 1 of CTX-8371 in Patients With Advanced Malignancies [Phase 1]
Phase 1 clinical trial evaluating CTX-8371 in patients with advanced malignancies, including Non-Small Cell Lung Cancer and Triple-Negative …