Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19) [Phase 1]
A Phase 1 trial evaluating the combination of adagrasib and nab-sirolimus in patients with advanced solid tumors and KRAS G12C-mutant non-sm…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Bronchoscopic Cryo-Immunotherapy of Lung Cancer [EARLY_Phase 1]
Early-phase Phase 1 trial update on bronchoscopic cryo-immunotherapy for advanced non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of sapanisertib in relapsed/refractory squamous non-small cell lung cancer (including NFE2L2-mutant and wild-type) has been te…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 pilot trial evaluating Tumor Treating Fields (TTFields) in combination with pembrolizumab as first-line therapy for advanced or me…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 safety and tolerability study of NC762 in patients with advanced or metastatic solid tumors has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Telehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung Cancer [NA]
Update on a terminated clinical trial evaluating telehealth-based synchronous navigation to improve molecularly-informed care for patients w…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Third-generation EGFR-TKI Treatment in Metastatic EGFR-mutant NSCLC
A trial update notes the completion of a study evaluating a third-generation EGFR-TKI in metastatic EGFR-mutant non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation [Phase 1]
Phase 1 clinical trial update of HMBD-001, an anti-HER3 antibody, evaluating its use with or without chemotherapy in solid tumors with NRG1 …
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Sitravatinib Plus Pembrolizumab in Patients With Advanced Treatment-Naïve PD-L1+ Non-Squamous NSCLC [Phase 2]
Phase 2 trial evaluating sitravatinib plus pembrolizumab in advanced treatment-naïve PD-L1-positive non-squamous non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: A Study to Evaluate Subcutaneous Durvalumab in Patients With Non-Small Cell Lung Cancer and Small Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating subcutaneous durvalumab for non-small cell lung cancer and small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure [Phase 3]
Phase 3 trial evaluating the combination of amivantamab and lazertinib with platinum-based chemotherapy versus platinum-based chemotherapy a…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure [Phase 3]
Phase 3 trial evaluating amivantamab and lazertinib with platinum chemotherapy versus platinum chemotherapy alone in EGFR-mutated locally ad…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Safety and Efficacy of Combination Osimertinib and Ipilimumab in Patients w EGFR Mutated NSCLC [Phase 1]
Phase 1 trial evaluating the safety and efficacy of combining osimertinib with ipilimumab in patients with EGFR-mutated non-small cell lung …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer [Phase 1, Phase 2]
Phase 1/2 study of endobronchial ultrasound-guided interstitial photodynamic therapy for locally advanced lung cancer was terminated, with r…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study of BMS-986315 and Nivolumab in Combination With Chemotherapy in Participants With First-line Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial of BMS-986315 in combination with nivolumab and chemotherapy for first-line Stage IV or recurrent non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma [Phase 1]
Phase Ib LXH254-centric combination study in non-small cell lung cancer and melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: SHR0302 Combined With PD-1/PD-L1 Inhibition for Treatment naïve or Acquired Resistant to Immunology NSCLC [Phase 2]
A Phase 2 trial evaluating SHR0302 in combination with PD-1/PD-L1 inhibitors for treatment-naive or immunotherapy-resistant non-small cell l…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: An Open Label Trial of Afatinib (Giotrif) in Treatment-naive (1st Line) or Chemotherapy Pre-treated Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s) [Phase 3]
An open-label Phase 3 trial evaluating afatinib (Giotrif) in EGFR-mutant locally advanced or metastatic non-small cell lung cancer, includin…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Alflutinib Mesylate Versus Gefitinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer （FLAG） [Phase 3]
Phase 3 trial comparing alflutinib mesylate to gefitinib in locally advanced or metastatic EGFR-sensitizing mutation-positive non-small cell…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial update of a JAB-3312–based combination therapy in adults with advanced solid tumors has completed (status: completed), inclu…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Phase 1b/2a, Open-label Study of Vactosertib in Combination With Durvalumab in Advanced NSCLC [Phase 1, Phase 2]
An open-label phase 1b/2a trial evaluating Vactosertib in combination with Durvalumab for advanced/metastatic non-small cell lung cancer has…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Ultrasound-guided Cryobiopsy of Mediastinal/Hilar Lymph Nodes [NA]
A clinical trial update reports ultrasound-guided cryobiopsy of mediastinal and hilar lymph nodes in non-small cell lung cancer and indicate…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases [Phase 2]
A Phase 2 trial of nivolumab and ipilimumab with chemotherapy for stage IV non-small cell lung cancer with brain metastases is currently act…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: RaFIST: A Radiomics-Based Tool for Intratumoral Fibrosis Stratification in Non-Small Cell Lung Cancer
This document reports the completion of a clinical trial evaluating RaFIST, a radiomics-based tool for stratifying intratumoral fibrosis in …
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: AB-16B5 Combined With Docetaxel in Subjects With Metastatic Non-Small Cell Lung Cancer (EGIA-002) [Phase 2]
This clinical trial update reports results from a Phase 2 study of AB-16B5 in combination with docetaxel for metastatic non-small cell lung …