Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495) [Phase 2]
This is a Phase 2 clinical trial update for a biomarker-directed pembrolizumab-based combination therapy in advanced non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Biomarker Screening Protocol for Participants With Solid Tumors
A clinical trial update describes a biomarker screening protocol for participants with solid tumors, and the study has been terminated.
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Tislelizumab in Combination With Sitravatinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating tislelizumab in combination with sitravatinib for locally advanced or metastatic non-small cell lung cancer was ter…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Clinical Outcomes of Tislelizumab Combined With Chemotherapy as Induction Therapy in Stage III (cTNM-IIIB/IIIC) NSCLC
The document reports clinical outcomes from a trial evaluating tislelizumab in combination with chemotherapy as induction therapy for stage …
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: The Food-effect on Alectinib Pharmacokinetics [NA]
A completed clinical trial evaluated the effect of food on the pharmacokinetics of alectinib in patients with non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: A Nutritional Supplement to Support People With Non-small Cell Lung Cancer [NA]
This clinical trial update notes an ongoing study of a nutritional supplement to support people with non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C) [Phase 2]
Phase 2 substudy evaluating pembrolizumab in combination with investigational agents for advanced non-small cell lung cancer in patients pre…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC) [Phase 1]
Phase 1 trial update of Xentuzumab (BI 836845) plus Afatinib in EGFR-mutant non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: CX3CR1+T Cell Predict Immunotherapy Efficacy
A completed clinical trial from Shanghai Pulmonary Hospital explored whether CX3CR1+ T cells can predict the efficacy of immunotherapy in no…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Complication and Lung Function Impairment Prediction Using Perfusion and CT Air Trapping
This completed trial from University Hospital, Montpellier investigates whether perfusion imaging and CT air trapping can predict treatment-…
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial [Phase 1]
The ARCHON-1 phase 1 trial updates on the safety of adding either Monalizumab or Oleclumab to Durvalumab with standard radiation therapy for…
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update reports results from a phase 1/2 study of the combination of telaglenastat hydrochloride and osimertinib in patie…
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: APG-2449 in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial of APG-2449 in patients with advanced solid tumors is currently recruiting, including non-small cell lung cancer, esophageal…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Long-term Outcomes Among Patients With Programmed Death-ligand 1 <1% Metastatic Non-small Cell Lung Cancer Treated With First-line Nivolumab + Ipilimumab + 2 Cycles of Chemotherapy
This update reports long-term outcomes from a first-line regimen of nivolumab plus ipilimumab with two cycles of chemotherapy for metastatic…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Phase Ib First in Human Dose Escalation of GT103 in Refractory, Advanced Stage Non-Small Cell Lung Cancer (TOP 1902) [Phase 1]
Phase Ib first-in-human dose-escalation study of GT103 in patients with refractory, advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Postoperative Telerehabilitation in Older Adults [NA]
A completed clinical trial from Pusan National University Hospital reports results of postoperative telerehabilitation for older adults with…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Study of CDX-585 in Patients With Advanced Malignancies [Phase 1]
Phase 1 trial update showing completed enrollment and results for CDX-585 in patients with advanced solid tumors, including non-small cell l…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) [Phase 2]
This Phase 2 platform trial comparing novel regimens against standard of care in non-small cell lung cancer has completed enrollment and pos…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Phase 1/2 Study of BA3071 in Patients With Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of BA3071 in patients with solid tumors, including non-small cell lung cancer and mel…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Immunotherapy With or Without SBRT in Patients With Stage IV Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating immunotherapy with or without SBRT in patients with stage IV non-small cell lung cancer has completed and posted …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02) [Phase 1, Phase 2]
AstraZeneca's Dato-DXd is being studied in a Phase 1/2 trial (TROPION-PanTumor02) in Chinese patients with advanced non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery [Phase 2]
This Phase 2 clinical trial update reports results for a hypofractionated boost before chemoradiation in patients with stage II–III non-smal…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer [Phase 4]
Pfizer's Phase 4 study of lorlatinib in ALK-positive non-small cell lung cancer has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Toward High Fidelity Adaptive Radiotherapy in the Thorax
Clinical trial update on high-fidelity adaptive radiotherapy in the thorax for non-small cell lung cancer; the study status is completed.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers [Phase 2]
Phase-2 study of dacomitinib in EGFR-driven advanced solid tumours, including non-small cell lung cancer and head and neck squamous cell car…