Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: An Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 trial comparing nivolumab alone, nivolumab plus ipilimumab, or nivolumab plus platinum-doublet chemotherapy versus platinum doublet …
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene [Phase 1, Phase 2]
A Phase 1/2 study of bemcentinib combined with standard chemoimmunotherapy in untreated advanced/metastatic non-small cell lung cancer with …
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: Anti-PD-L1 in Stage IIIA(N2) Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial of an anti-PD-L1 therapy in stage IIIA(N2) non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Atezolizumab and Stereotactic Body Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer [Phase 1]
This Phase 1 clinical trial update evaluates atezolizumab in combination with stereotactic body radiation therapy for Stage I non-small cell…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy [Phase 2]
Phase II umbrella study evaluating multiple novel anti-cancer agents in non-small cell lung cancer patients who progressed on anti-PD-1/PD-L…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1) [Phase 1, Phase 2]
Phase 1/2 study assessing Zidesamtinib (NVL-520) in patients with ROS1-rearranged non-small cell lung cancer and other ROS1-rearranged solid…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial of Telisotuzumab vedotin in adults with advanced/metastatic non-squamous non-small cell lung cancer was terminated, with res…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Korea Osimertinib Real World Evidence Study to Assess Safety and Efficacy - PLUS
A completed real-world evidence study in Korea assessed the safety and efficacy of osimertinib for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement [Phase 1]
A first-in-human Phase 1 trial of PF-07284890 in patients with BRAF V600 mutant solid tumors, including those with brain involvement, has be…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 [Phase 2]
Phase 2 trial evaluating the combination of recombinant EphB4-HSA fusion protein with pembrolizumab has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment [Phase 2]
Clinical trial update on a Phase 2 study of sotorasib (Lumakras) for first-line treatment of stage IV KRAS p.G12C-mutant non-small cell lung…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Premedication to Reduce Amivantamab Associated Infusion Related Reactions [Phase 2]
Phase 2 trial update examining premedication to reduce infusion-related reactions with amivantamab in non-small cell lung cancer; results ha…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC [Phase 2]
A Phase 2 study of PULSAR-ICI with or without IMSA101 in patients with oligometastatic non-small cell lung cancer and renal cell carcinoma w…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: A First-in-human Study to Learn How Safe the Study Treatment BAY2862789 is, to Find the Best Dose, How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, and How it Acts on Different Tumors in Participants With Advanced Solid Tumors [Phase 1]
This first-in-human Phase 1 study of BAY2862789 aims to assess safety, determine the recommended dose, characterize pharmacokinetics/pharmac…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 trial of HMBD-002, a VISTA-targeting monoclonal antibody, as monotherapy and with pembrolizumab in patients with…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation [Phase 1]
Phase 1 trial evaluating PRT3789 as monotherapy or in combination with docetaxel in SMARCA4-mutant advanced/metastatic solid tumors has comp…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC [Phase 2]
A Phase 2 trial evaluating osimertinib in combination with chemotherapy for uncommon EGFR-mutant non-small cell lung cancer has been termina…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Phase II Clinical Trial of NIVO-IPI-TAXANE in Untreated Metastatic NSCLC [Phase 2]
Phase II results have been posted for a nivolumab-ipilimumab-taxane regimen in untreated metastatic non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Long-Term Safety Outcomes and First-Line Treatment Patterns in Patients With Non-Small Cell Lung Cancer and Programmed Death-1 (Pd-L1) <1%
Clinical trial update describing long-term safety outcomes and initial first-line treatment patterns in patients with non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer [Phase 1]
A Phase 1 study evaluating TAS2940 in locally advanced or metastatic solid tumors has been terminated. The trial enrolled patients with glio…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation. [Phase 2]
This is a Phase 2 clinical trial evaluating JDQ443 as a single-agent first-line therapy for locally advanced or metastatic KRAS G12C-mutated…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications [Phase 1]
Phase 1 safety, tolerability, and pharmacokinetics study of AMG 794 in Claudin-6–positive cancers, including non-small cell lung cancer and …
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer [Phase 2]
A phase 2 trial is evaluating the combination of atezolizumab and cobimetinib in patients with metastatic, recurrent, or refractory non-smal…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Immunotherapy in Patient With Poor General Condition [Phase 2]
A Phase 2 trial update reports on immunotherapy for patients with advanced non-small cell lung cancer and poor general condition. The study …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated safety and preliminary effectiveness of BGB-A445 in combination with tislelizumab in participants with advanced…