Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC [Phase 3]
A Phase 3 trial evaluating BAT3306 plus chemotherapy versus Keytruda (pembrolizumab) in non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: RAPART in Locally Advanced Non-small Cell Lung Cancer Patients [NA]
RAPART trial in locally advanced non-small cell lung cancer is currently recruiting at Capital Medical University.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Application of Methylation Markers in Early Detection and MRD Monitoring of Lung Cancer
This clinical trial evaluates methylation markers for early detection and minimal residual disease monitoring in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the safety and efficacy of a WSD0922-FU combination with Osimertinib in non-small cell lung cancer;…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Adjuvant Chemotherapy for High-Risk Pathologic Stage I Non-Squamous NSCLC
This is a clinical trial update about adjuvant chemotherapy for high-risk pathologic stage I non-small cell lung cancer. The trial status is…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: KEYMAKER-U01 Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-01B/KEYMAKER-U01B) [Phase 2]
A Phase 2 trial evaluating pembrolizumab with investigational agents in treatment-naïve PD-L1-positive advanced non-small cell lung cancer h…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating platinum-based doublet chemotherapy with proton beam radiation for unresectable stage II–III non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers [Phase 1]
Phase 1 clinical trial evaluating hypofractionated radiotherapy in combination with durvalumab (MEDI4736) and tremelimumab in patients with …
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Real-world First-line Sugemalimab-Chemotherapy in Advanced NSCLC [NA]
This document reports that a real-world, first-line trial of sugemalimab in combination with chemotherapy for advanced non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Study of Participants With Advanced Non-Small Cell Lung Cancer Treated With Nivolumab in France After at Least One Prior Chemotherapy-based Treatment by Lung Initiative on Sequence Therapy
A completed ClinicalTrials.gov study evaluating nivolumab in patients with advanced non-small cell lung cancer in France after prior chemoth…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Study of Nivolumab in Participants With Locally Advanced or Metastatic (Stage IIIB-IV) Non-Small Cell Lung Cancer (NSCLC) With Squamous and Non-Squamous Histology After Prior Chemotherapy Treated in Real World Settings in Greece and Cyprus
This completed clinical trial evaluated nivolumab for locally advanced or metastatic non-small cell lung cancer in patients previously treat…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Multimodal Model Predicts Treatment Efficacy and CIP Risk in Advanced NSCLC With Immunotherapy and Chemotherapy
A completed clinical trial evaluating a multimodal model that predicts treatment efficacy and the risk of checkpoint inhibitor pneumonitis i…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. [Phase 2, Phase 3]
Phase 2/3 DETERMINE trial treatment arm 05 is evaluating the combination of vemurafenib and cobimetinib in adults with BRAF-positive cancers…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors [Phase 1]
Phase 1 study evaluating CFT1946 as monotherapy and in combination for BRAF V600-mutant solid tumors to assess safety, tolerability, and pre…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial [NA]
Completed clinical trial evaluating a supportive care intervention (ROAR-LCT) for patients with advanced non-small cell lung cancer and smal…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Firmonertinib in the Treatment of EGFR(+) NSCLC Patients With Central Nervous System Metastasis
The clinical trial evaluating Firmonertinib for EGFR-positive non-small cell lung cancer patients with central nervous system metastasis has…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Treatment of Multifocal Lung Adenocarcinoma [NA]
This entry notes a Mayo Clinic-sponsored clinical trial for multifocal lung adenocarcinoma. The study status is TERMINATED.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus Platinum-Based Chemotherapy in Participants With Previously Untreated Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial comparing Tobemstomig plus platinum-based chemotherapy against Pembrolizumab plus platinum-based chemotherapy in previously un…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of furmonertinib in patients with locally advanced or metastatic non-small cell lu…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr [Phase 3]
Phase 3 trial update evaluating dual immune checkpoint inhibitors in PD-L1-positive stage IV non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Phase 2 Study of Maintenance OSI-906 Plus Erlotinib (Tarceva®), or Placebo Plus Erlotinib in Patients With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy [Phase 2]
Phase 2 maintenance trial evaluating OSI-906 plus erlotinib versus placebo plus erlotinib in nonprogressors of platinum-based chemotherapy i…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene [Phase 2]
Phase 2 clinical trial evaluating Erlotinib in combination with OSI-906 in adults with advanced non-small cell lung cancer carrying activati…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Lung Cancer With Copanlisib and Durvalumab [Phase 1]
Phase 1 trial update on the combination of copanlisib and durvalumab for non-small cell lung cancer has completed its Phase 1 portion.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC [Phase 2]
Phase 2 trial evaluating atezolizumab in combination with 8 Gy single-fraction radiotherapy for advanced oligoprogressive non-small cell lun…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 randomized study comparing docetaxel alone versus docetaxel with bintrafusp alfa in advanced non-small cell lung cancer was termin…