Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Study of High Efficient Killing Cell Therapy for Advanced NSCLC [Phase 1]
A Phase 1 clinical trial of a high-efficiency killing cell therapy for advanced non-small cell lung cancer is currently recruiting. No effic…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Preoperative Sintilimab Combined With Bevacizumab and Chemotherapy for Resectable Non-Small Cell Lung Cancer [NA]
Clinical trial investigating preoperative sintilimab with bevacizumab and chemotherapy for resectable non-small cell lung cancer is currentl…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Real-world Observational Study of Targeted Therapy in Patients With Advanced ROS1-positive NSCLC
This clinical trial update describes a real-world observational study of targeted therapies in patients with advanced ROS1-positive non-smal…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Neoadjuvant Toripalimab for Clinically Stage II-IIIB Resectable Non-small Cell Lung Cancer with EGFR Mutation and PD-L1 Positive Expression [Phase 2]
Phase 2 neoadjuvant trial of toripalimab for clinically stage II-IIIB resectable non-small cell lung cancer with EGFR mutation and PD-L1 pos…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067 [Phase 1, Phase 2]
Phase 1a/Phase 2 study evaluating safety, preliminary efficacy, PK and PD of ST-067 in various cancers; currently recruiting.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Real-world Study of Local Therapy Changes During 1L Lorlatinib in Unresectable ALK+ NSCLC
Real-world study examining how local therapy decisions change during first-line lorlatinib treatment for unresectable ALK-positive non-small…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC [Phase 1, Phase 2]
Phase 1b/Phase 2 single-arm trial evaluating golidocitinib in combination with an anti-PD-1 agent for previously treated non-small cell lung…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Neoadjuvant Chemotherapy Sequentially Combined with Sintilimab in Resectable EGFR-Mutant NSCLC [Phase 2]
A Phase 2 trial evaluating neoadjuvant chemotherapy sequentially combined with Sintilimab in resectable EGFR-mutant non-small cell lung canc…
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: Perioperative Treatment Outcomes of Early NSCLC
This document provides a clinical trial update on perioperative treatment outcomes for early non-small cell lung cancer. Enrollment is by in…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN) [Phase 2]
A multicenter, single-arm Phase 2 trial evaluating AK112 in combination with chemotherapy as first-line treatment for patients with non-squa…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Personalized Neoantigen MRNA Vaccine Combined with Adebrelimab in Non-Small Cell Lung Cancer Patients [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating a personalized neoantigen mRNA vaccine in combination with the PD-1 inhibitor adebrelimab for non…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Lorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial update evaluating lorlatinib as neoadjuvant therapy for stage IB-IIIB ALK-rearranged non-small cell lung cancer; th…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Clinical trial update for SHR-A2102 in combination with Adebrelimab and SHR-8068 for locally advanced or metastatic non-small cell lung canc…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: AI-guided Prognostication and Cranial Radiotherapy Optimization in EGFR-TKI-treated Non-small Cell Lung Cancer Patients With Baseline Brain Metastases
An ongoing study from Fudan University evaluating AI-guided prognostication and cranial radiotherapy optimization in EGFR-TKI–treated patien…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Transbroncheal Novel PDT Peripheral Lung Tumor Ablation With 5-ALA [NA]
This clinical trial aims to evaluate transbronchial photodynamic therapy using 5-ALA for peripheral lung tumors; the trial is not yet recrui…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Almonertinib Versus Placebo as Adjuvant Therapy in Resected Stage II-IIIB Non-Small Cell Lung Cancer With EGFR-sensitive Mutations [Phase 3]
A Phase 3 trial compares almonertinib to placebo as adjuvant therapy after surgical resection in stage II-IIIB non-small cell lung cancer wi…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: ICI Rechallenge for Advanced NSCLC With Long-Term Response to First-Line ICI [Phase 2]
A Phase 2 trial assessing rechallenge with immune checkpoint inhibitors in advanced Non-small cell lung cancer patients who previously had a…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Furmonertinib 160mg as First-line Treatment in Locally Advanced or Metastatic NSCLC With EGFR Classical Mutations [Phase 3]
Phase 3 trial evaluating furmonertinib 160 mg as first-line therapy for locally advanced or metastatic non-small cell lung cancer with EGFR …
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit [NA]
The document provides an update on a completed clinical performance study protocol for the Therascreen KRAS RGQ PCR Kit in non-small cell lu…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Phase 1/2 Study of HS-10375 in Patients with Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the investigational drug HS-10375 for advanced or metastatic non-small cell lung c…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC [Phase 2]
A Phase 2 study is evaluating osimertinib plus stereotactic radiosurgery (SRS) versus osimertinib alone in patients with EGFR-positive non-s…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy [Phase 2]
Phase 2 trial evaluating tislelizumab for stage III non-small cell lung cancer after neoadjuvant therapy, with optional bevacizumab and defi…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers [Phase 1]
This document reports a Phase 1 clinical trial of NI-1801 for mesothelin-expressing solid cancers, with recruiting status and multiple indic…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: Stereotactic Ablative Radiotherapy for Oligometastatic Non-small Cell Lung Cancer [NA]
The trial evaluating stereotactic ablative radiotherapy for oligometastatic non-small cell lung cancer is currently active but not recruitin…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: A Study of XZB-0004 in Patients With Solid Tumors [Phase 1]
Phase 1 study of XZB-0004 in patients with solid tumors, including non-small cell lung cancer, is currently recruiting.