Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Lorlatinib Compared with Concurrent/ Sequential Chemoradiotherapy in Stage III ALK Positive Lung Adenocarcinoma [Phase 3]
A Phase 3 trial is planned to compare lorlatinib with concurrent or sequential chemoradiotherapy in stage III ALK-positive non-small cell lu…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases [Phase 1]
A Phase 1 safety study evaluating a gamma-delta T cell product in combination with low-dose radiotherapy for locally advanced or metastatic …
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: The Efficacy and Safety of the Bispecific Anti-PD-1/PD-L1 Antibody IBI318 Combined with Lenvatinib in NSCLC. [Phase 2]
Phase 2 clinical trial investigating the efficacy and safety of the bispecific anti-PD-1/PD-L1 antibody IBI318 in combination with lenvatini…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Construction of a Prognostic and Prediction Model for Perioperative Immunotherapy in NSCLC: A Multi - Omics Perspective
This trial aims to construct a multi-omics prognostic and predictive model to guide perioperative immunotherapy in non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: A Prospective Study Investigating the Relationship Between Minimal Residual Disease Detection, Monitoring Frequency, and Prognosis in Non-small Cell Lung Cancer Patients Eligible for Curative Treatment.
A prospective study from Japan will evaluate how detecting minimal residual disease and the frequency of monitoring relate to prognosis in p…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Alone or Combined with Anlotinib Administered Prior to Surgery in Terms of Pathological Complete Response [Phase 2]
This clinical trial update outlines a two-cohort Phase 2 exploratory study evaluating benmelstobart alone or in combination with anlotinib b…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Personalized DC Vaccine for Postoperative Cancer [Phase 1]
A Phase 1 clinical trial evaluating a personalized dendritic cell vaccine for postoperative gastric cancer and hepatocellular carcinoma is c…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Study of Longitudinal Plasma PD-L1 Testing With Immunotherapy in Lung Cancer [NA]
A Ballad Health-sponsored clinical trial is evaluating longitudinal plasma PD-L1 testing in non-small cell lung cancer patients treated with…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Vapor Ablation for Localized Cancer Lesions [NA]
Clinical trial update indicating vapor ablation therapy is not yet recruiting for localized cancer lesions, including non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Immunotherapy Combined with Hypofractionated Concurrent Chemoradiotherapy Followed by Immunotherapy in LA-NSCLC [Phase 2]
A Phase 2 clinical trial update from Peking University investigates immunotherapy with hypofractionated concurrent chemoradiotherapy followe…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Xingbai Ji Formula Combined with Chemotherapy and Sintilimab in Metastatic Multi-Target Mutation-Negative Non-Small Cell Lung Cancer: a Clinical Trial [NA]
A clinical trial update describing a study of Xingbai Ji Formula combined with chemotherapy and Sintilimab for metastatic multi-target mutat…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: DREAM Study: DNA/RNA-NGS Co-Testing in Driver-Negative, Treatment-Resistant NSCLC
The DREAM Study is a clinical trial evaluating DNA/RNA next-generation sequencing co-testing for driver-negative, treatment-resistant non-sm…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Establishing a Longitudinal Cohort Study of Lung Cancer Using Tissue and Peripheral Blood Metabolomics.
This ClinicalTrials.gov entry describes a longitudinal cohort study of lung cancer using tissue and peripheral blood metabolomics, currently…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study evaluating AL3818 in combination with nivolumab for solid tumors; the trial is currently not recr…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies [Phase 1]
A Phase 1 study of TGRX-1942 for advanced solid tumors and/or relapsed/refractory hematologic malignancies is currently recruiting in China.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: TGRX-326 Pharmacokinetic Mass Balance [Phase 1]
A Phase 1 pharmacokinetic mass balance study of TGRX-326 in non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Additional Chemotherapy for EGFRm Patients with the Continued Presence of Plasma CtDNA EGFRm At Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG) [Phase 2]
Phase 2 trial (PACE-LUNG) evaluating additional chemotherapy in EGFR mutation-positive non-small cell lung cancer patients who have persiste…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Association Between RVT and Prognosis After Neoadjuvant Targeted Therapy in EGFR NSCLC
This clinical trial update describes a study to assess the association between RVT and prognosis after neoadjuvant targeted therapy in EGFR-…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists [NA]
A clinical trial update aimed at identifying predictive factors of response to PD-1/PD-L1 inhibitors across multiple cancers, including mela…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Injection of 99mTc-nanocolloid and ICG to Identify, Retrieve and Qualify TDLN in Early-stage NSCLC [NA]
A clinical trial update describing the use of Technetium-99m nanocolloid and Indocyanine Green to identify sentinel lymph nodes in early-sta…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Neoadjuvant Chemotherapy Combined With Bispecific Antibody Versus Monoclonal Antibody in Locally Advanced NSCLC [Phase 2]
Phase 2 trial update comparing neoadjuvant chemotherapy plus a bispecific antibody versus a monoclonal antibody in locally advanced non-smal…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Broncho-Vascular Lung Sparing Reconstructions and Pneumonectomies in Patients With Non Small Cell Lung Cancer
This clinical trial update describes a study evaluating broncho-vascular lung-sparing reconstructions and pneumonectomies in patients with n…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Primary Tumor Resection With EGFR TKI for Stage IV NSCLC [Phase 2]
Phase 2 trial evaluating primary tumor resection with an EGFR tyrosine kinase inhibitor for stage IV non-small cell lung cancer; the study i…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Detection of Circulating Tumour Cells, Spread Through Air Space in Patients With Lung Cancer
This clinical trial is investigating the detection of circulating tumor cells and the spread through air space in patients with non-small ce…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical study evaluating nanocrystalline megestrol in malnourished patients with first-line non-small cell lung cancer. The trial s…