Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation [Phase 3]
Phase 3 trial update: JAB-21822 in combination with JAB-3312 versus standard of care in first-line treatment of advanced non-small cell lung…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Study on c-Met Targeted PET/CT Imaging in NSCLC [NA]
A clinical trial is evaluating a c-Met targeted PET/CT imaging tracer in non-small cell lung cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With NSCLC [Phase 2]
A Phase 2 clinical trial update on PM8002 (anti-PD-L1/VEGF) in combination with chemotherapy for non-small cell lung cancer, currently activ…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab [Phase 4]
Phase 4 clinical trial evaluating chemoradiotherapy with surgery followed by consolidation durvalumab for non-small cell lung cancer (stage …
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Quality of Life as a Predictor of OS and PFS in Patients With Lung Cancer
The trial update discusses analyzing quality of life as a potential predictor of overall survival and progression-free survival in patients …
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Integrating Surgery and Radiotherapy Following Tislelizumab-based Conversion Therapy in N3-Stage III NSCLC [Phase 2]
Phase 2 trial update evaluating tislelizumab-based conversion therapy followed by surgery and radiotherapy for N3-stage III non-small cell l…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: A Phase Ⅱ Study Assessing the Safety and Efficacy of PLB1004 in EGFR ex20ins Mutation Patients With Advanced and Metastatic Non-small Cell Lung Cancer(NSCLC) [Phase 2]
A Phase 2 study is evaluating the safety and efficacy of PLB1004 in patients with EGFR exon 20 insertion-mutant advanced or metastatic non-s…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Genotyping of Ebus-tbna Supernant Cell-free Dna in Nsclc
A clinical trial update indicates a study on genotyping endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) superna…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO
This clinical trial update announces ongoing recruitment for the TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO study led by Un…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Assessment of PET Tracers to Evaluate T Cell Change and Activation in Relation to Immunotherapy Treatment Response in Non-Small Cell Lung Cancer [NA]
Clinical trial evaluating PET tracers to assess T cell changes and activation in relation to immunotherapy response in non-small cell lung c…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Exploratory Biomarker Analysis of Neoadjuvant Chemoimmunotherapy Followed by Pulmonary Resection in Stage II-III Non-Small Cell Lung Cancer
This clinical trial update indicates ongoing recruitment for an exploratory biomarker analysis of neoadjuvant chemoimmunotherapy followed by…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Toripalimab Therapy After Resection in High-risk Stage IA2-IB NSCLC With no Driver Alterations (EGFR or ALK) [Phase 2]
A Phase 2 trial evaluating toripalimab as postoperative therapy after surgical resection in high-risk stage IA2-IB non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial is evaluating whether de-escalating the duration of maintenance immunotherapy benefits patients with stage …
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CLINICAL_TRIALS research · 2025-03-31Clinical Trial Update: SERS-Based Serum Molecular Spectral Screening for Lung Cancer Type
The document reports a not-yet-recruiting clinical trial evaluating a SERS-based serum spectral screening method for lung cancer type differ…
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CLINICAL_TRIALS research · 2025-03-31Clinical Trial Update: Molecular Imaging of FAP Expressing Cancer-associated Fibroblasts in NSCLC Treated With Immune-checkpoint Inhibitors [NA]
Clinical trial investigating molecular imaging of FAP-expressing cancer-associated fibroblasts in non-small cell lung cancer patients treate…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: A Study of the Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases [Phase 2]
A Phase 2 trial is evaluating intraventricular pemetrexed plus nivolumab for refractory non-squamous non-small cell lung cancer with leptome…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Stage III NSCLC
This clinical trial update describes the validation and benchmarking of top-performing ctDNA diagnostic tests for stage III non-small cell l…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: [18F]F-AraG PET Imaging to Visualize Tumor Infiltrating T-cell Activation in Non-small Cell Lung Cancer. [NA]
A clinical trial update notes imaging with the tracer [18F]F-AraG to visualize tumor-infiltrating T-cell activation in non-small cell lung c…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Long-term Follow-up of Checkpoint Inhibitors-induced Ileo-colitis
A clinical trial update describing long-term follow-up of immune checkpoint inhibitor–induced ileocolitis and ongoing recruitment for patien…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: A Clinical Imaging Study of the Changes in [18F]F-AraG Uptake Following Anti-PD-1 Therapy in Non-small Cell Lung Cancer [NA]
A clinical imaging study evaluating changes in [18F]F-AraG uptake after anti-PD-1 therapy in advanced non-small cell lung cancer. The study …
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Chest Lymph Node Sampling in Patients With Advanced Lung Cancer to be Treated With Curative-intent Radiation Treatment [NA]
An ongoing clinical trial evaluating chest lymph node sampling in patients with advanced non-small cell lung cancer who are to receive curat…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating AP203 in patients with locally advanced or metastatic solid tumors, including non-small cell …
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Liquid Biopsy Assay of EBUS-TBNA Supernatant Fluid for Diagnosing Lung Cancer
Clinical trial update describing a liquid biopsy assay using EBUS-TBNA supernatant fluid to diagnose lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Cisplatin (CIS) Administered As Dry Powder for Inhalation (DPI) in Patients with Stage IV Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/2 study of cisplatin delivered as a dry powder inhalation in patients with Stage IV non-small …
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics [Phase 4]
This clinical trial registry entry outlines a Phase 4 study investigating mechanisms of resistance to lorlatinib induction therapy in resect…