Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Liquid Biopsy-Based Novel Modality for Postoperative Management of Lung Cancer [NA]
A new clinical trial is evaluating a liquid biopsy-based modality for postoperative management of non-small cell lung cancer and is currentl…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Phase II Randomized Trial of Carboplatin+Pemetrexed+Bevacizumab+/- Atezolizumab in Stage IV NSCLC [Phase 2]
Phase II randomized trial at Fox Chase Cancer Center evaluating adding atezolizumab to carboplatin, pemetrexed, and bevaciuzmab vs. standard…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer
A clinical trial updating on safety, efficacy, and survival outcomes for neoadjuvant/induction immunotherapy in surgical and radiotherapeuti…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: A Clinical Study of Furmonertinib in the Treatment of EGFR-Mutated NSCLC With Leptomeningeal Metastases
Clinical trial update for furmonertinib in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis; the study is currently ac…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients) [NA]
This document reports an update on the AIM-HIGH trial evaluating adjuvant chemotherapy in intermediate/high-risk stage I or stage IIA non-sq…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: A Study Evaluating the Effect of Aumolertinib on the Pharmacokinetics of Midazolam in Patients With NSCLC [Phase 1]
This Phase 1 trial assesses the effect of Aumolertinib on the pharmacokinetics of midazolam in patients with non-small cell lung cancer. It …
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Resistance Mechanisms and Sequential Treatment Strategies Following First-Line Lorlatinib in ALK-Positive NSCLC
This clinical trial update outlines planned research on resistance mechanisms and sequential treatment strategies following first-line lorla…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Prospective Cohort Study Evaluating 18FDG PET-CT for the Early Prediction of the Efficacy of Immunotherapy Associated or Not With Chemotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Broncho-Pulmonary Carcinoma
A prospective cohort study sponsored by Centre Antoine Lacassagne is evaluating whether 18F-FDG PET-CT can predict early response to immunot…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. [Phase 3]
A Phase 3 trial evaluating sacituzumab govitecan plus zimberelimab for patients with non-small cell lung cancer confined to the chest who ha…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: New Adjuvant Trial of Chemotherapy vs Chemo-immunotherapy [Phase 3]
A Phase 3 trial compares adjuvant chemotherapy alone to chemo-immunotherapy in non-small cell lung cancer. The study is currently active but…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: DUMAS: Neo-Adjuvant Immunotherapy for Pancoast Tumors [Phase 2]
This clinical trial update describes a Phase 2 study called DUMAS evaluating neo-adjuvant immunotherapy for Pancoast tumors associated with …
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating XP-102 in combination with trametinib for BRAF V600-mutant advanced solid tumors; the study is not yet…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Clinical Trial of AMG510 in Stage III Unresectable NSCLC KRAS p.G12C Patients and Ineligible for Chemo-radiotherapy [Phase 2]
Phase 2 clinical trial update for AMG510 (sotorasib) in patients with unresectable stage III non-small cell lung cancer harboring KRAS G12C …
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Personalizing Adoptive Cell Transfer for Solid Tumors: Towards a New Patient-tailored Treatment Option
The study outlines a personalized adoptive cell transfer approach for solid tumors, including non-small cell lung cancer. It is currently no…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Lung Cancer Registry
A ClinicalTrials.gov registry entry for the Lung Cancer Registry (NCT04654364) shows the study is currently recruiting. The conditions inclu…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: MYLUNG Consortium Study Protocol 2
Update on the MYLUNG Consortium Study Protocol 2 for non-small cell lung cancer; the study is listed as active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO) [Phase 2]
This document reports a Phase 2 clinical trial update examining atezolizumab in combination with induction chemotherapy and radiotherapy for…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGFR-mutated Lung Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of chemotherapy with osimertinib in metastatic EGFR-mutated non-small cell lung cancer (lu…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: NADIM II: Neo-Adjuvant Immunotherapy [Phase 2]
NADIM II is a Phase 2 neoadjuvant immunotherapy trial for non-small cell lung cancer; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors [Phase 1]
This document describes a Phase Ib trial of HS-20117 in combination with other drugs for advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs [Phase 3]
Phase 3 clinical trial evaluating Glumetinib in combination with Osimertinib Mesylate versus platinum-based chemotherapy in non-small cell l…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation [Phase 1, Phase 2]
An early-phase Phase 1/2a trial evaluating the combination of JAB-21822 and JAB-3312 in KRAS p.G12C-mutant advanced solid tumors, including …
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1 [Phase 1, Phase 2]
Phase 1/2 study of JAB-21822 in advanced or metastatic non-small cell lung cancer with KRAS p.G12C and STK11 co-mutation and KEAP1 wild-type…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy [Phase 3]
A Phase 3 trial comparing furmonertinib to placebo in EGFR mutation-positive stage II-IIIA non-small cell lung cancer after complete resecti…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer [Phase 2]
Phase 2 trial evaluating dose-attenuated chemotherapy in compromised patients with lung cancer is currently recruiting. The study includes b…