Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: The Lung Health Check Pilot [NA]
Clinical trial update for the Lung Health Check Pilot; the study on non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006) [Phase 3]
Phase 3 study MK-7684A-006 is evaluating pembrolizumab/vibostolimab with concurrent chemoradiotherapy, followed by maintenance pembrolizumab…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Perioperative Study of Iparomlimab and Tuvonralimab in Resectable NSCLC [Phase 2]
Phase 2 perioperative trial evaluating iparomlimab and tuvonralimab in resectable non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer [Phase 2, Phase 3]
A study of HS-20117 in combination with Aumolertinib is being conducted for advanced non-squamous non-small cell lung cancer in Phase 2/3, a…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT) [NA]
This TWiCs trial compares acute toxicity of single-fraction versus multiple-fraction SBRT for metastasis-directed treatment across several c…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: CT-95 in Advanced Cancers Associated With Mesothelin Expression [Phase 1]
Phase 1 trial CT-95 for mesothelin-expressing tumors is currently recruiting across multiple indications, including epithelial ovarian cance…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: SDTM001 Injection as Adjuvant Therapy for NSCLC Patients After Radical Surgical Resection [Phase 1]
Phase 1 clinical trial update for SDTM001 Injection as adjuvant therapy in patients with Non-Small Cell Lung Cancer after radical surgical r…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients
This document describes the EMPATHY NSCLC study, a European registry for plasma-based molecular profiling in patients with advanced non-smal…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Role of Cancer-associated Fibroblast, MDSCs and Immune Cell Interplays in the Resistance of Non-small Cell Lung Cancer to Anti-PD1/PD-L1 Therapies
This clinical trial examines how cancer-associated fibroblasts, myeloid-derived suppressor cells, and immune cell interactions contribute to…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Consolidation Radiotherapy vs. Observation in Oligoresidual Advanced Non-Small Cell Lung Cancer After Chemo-Immunotherapy [Phase 2]
Phase 2 clinical trial comparing consolidation radiotherapy versus observation in oligoresidual advanced non-small cell lung cancer after ch…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor [Phase 1, Phase 2]
Update on a Phase I/II autologous engineered TCR T-cell therapy trial for advanced pancreatic ductal adenocarcinoma, non-small cell lung can…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients [Phase 2]
This update describes a Phase 2 trial evaluating the combination of pembrolizumab and lenvatinib in PD-L1 positive, TKI-resistant non-small …
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Role of MDSCs and Cancer Stem Cells and Their Cross Talks in NSCLC
A clinical trial update describes investigation into the roles of myeloid-derived suppressor cells and cancer stem cells and their interacti…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Effect of G-CSF on MDSC and Cancer Stem-cells Interactions in Non-small Cell Lung Cancers (CIRCUIT) [NA]
Clinical trial CIRCUIT investigates how granulocyte colony-stimulating factor affects interactions between MDSCs and cancer stem cells in no…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Trial for Local Ablative Treatment (LAT) Optimization in Patients With Advanced Non-Small Cells Lung Cancer (NSCLC) Presenting an Anaplastic Lymphoma Kinase (ALK) Rearrangement Treated by Brigatinib [Phase 2]
Phase 2 trial assessing local ablative treatment optimization in advanced ALK-rearranged non-small cell lung cancer patients treated with br…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases [Phase 4]
A Phase 4 trial evaluating firmonertinib in combination with intrathecal injection for EGFR-mutant non-small cell lung cancer with leptomeni…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Tislelizumab Combined With Anlotinib and Nab-paclitaxel in III Resectable Non-small Cell Lung Cancer(TitAN) : A Prospective, Single-Arm, Phase II Study [Phase 2]
A prospective Phase II, single-arm trial evaluating tislelizumab in combination with anlotinib and nab-paclitaxel in III resectable non-smal…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Anti-CD38 Antibody With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial tests an anti-CD38 antibody with a KRAS vaccine and an anti-PD-1 antibody in pancreatic ductal adenocarcinoma and r…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Ruxolitinib for Cancer Cachexia [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating ruxolitinib for cancer cachexia in patients with stage IV non-small cell lung cancer, and the …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase Ib/II Study of Vebreltinib With Furmonertinib in NSCLC Patients With c-Met Amplification After EGFR-TKI Failure [Phase 1, Phase 2]
Phase Ib/II study evaluating the combination of vebreltinib with furmonertinib for non-small cell lung cancer with c-Met amplification after…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer：A Prospective, Single-Arm, Phase II Study [Phase 2]
This document updates an ongoing, single-arm Phase II trial evaluating tislelizumab with sCRT (short-course chemoradiotherapy) in stage IIIB…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Electroacupuncture Combined With PD-1 Inhibitor for Elderly Patients With Advanced NSCLC [NA]
A clinical trial is evaluating electroacupuncture combined with a PD-1 inhibitor in elderly patients with advanced non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: A Phase II Randomized Trial of Neoadjuvant Ivonescimab or Penpulimab Plus Chemotherapy in Resectable NSCLC [Phase 2]
A Phase II randomized trial is evaluating neoadjuvant Ivonescimab or Penpulimab plus chemotherapy in resectable non-small cell lung cancer, …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase I/II Study of PLB1004 Combined With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation-positive [Phase 1, Phase 2]
Phase I/II trial evaluating PLB1004 in combination with platinum-based chemotherapy in EGFR mutation-positive non-small cell lung cancer; th…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLC [Phase 2]
Phase 2 trial evaluating perioperative treatment with sunvozertinib for stage II-IIIB non-small cell lung cancer is currently recruiting.