Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Dose-escalation and Dose-expansion Phase I/Phase II Clinical Study of Dositinib Mesylate Tablets (90-1408) in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer With Positive EGFR Mutation [Phase 1, Phase 2]
A dose-escalation and dose-expansion Phase I/II clinical study of Dositinib Mesylate Tablets for locally advanced or metastatic non-small ce…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression [Phase 1, Phase 2]
Clinical trial update for BT5528-100 (Phase 1/2) in EphA2-expressing advanced solid tumors. The study includes urothelial carcinoma, ovarian…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of BL-M07D1 vs Pembrolizumab-platinum Chemotherapy in First-line Treatment of HER2-mutant Advanced or Metastatic Non-squamous NSCLC [Phase 3]
Phase 3 trial evaluating BL-M07D1 versus pembrolizumab plus platinum-based chemotherapy as first-line treatment for HER2-mutant advanced or …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
This is a screening study by TScan Therapeutics to collect samples for tumor-associated antigens, HLA typing, and HLA loss of heterozygosity…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer [Phase 3]
This Phase 3 trial compares SB27, a pembrolizumab biosimilar, with Keytruda (pembrolizumab) in patients with metastatic non-squamous non-sma…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating YL201 in combination with Ivonescimab (AK112) for advanced solid tumors, including non-small cell lung…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases [Phase 2]
Phase 2 trial evaluating whether online adaptive stereotactic radiotherapy can eliminate planning target volume (PTV) margins in early-stage…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis [Phase 2]
Phase 2 clinical trial investigating MRI-guided adaptive stereotactic radiotherapy to eliminate planning target volume margins in non-small …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: The Impact of Thymosin α-1 on the Efficacy of Concurrent Chemoradiotherapy Followed by Immunotherpay Consolidation for Locally Advanced NSCLC [Phase 2]
Phase 2 trial investigating whether Thymosin α-1 enhances the efficacy of concurrent chemoradiotherapy followed by immunotherapy consolidati…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies [Phase 1, Phase 2]
Clinical trial update for BT8009-100 in nectin-4 expressing advanced malignancies (Phase 1/2) with status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery
This clinical trial evaluates whether longer duration of smoking cessation before lung cancer surgery reduces postoperative complications in…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS [Phase 1, Phase 2]
A Phase 1/Phase 2 study evaluating RMC-6236 in patients with advanced solid tumors harboring RAS mutations, including non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC [Phase 2]
A Phase 2 study evaluating EIK1001 in combination with pembrolizumab and chemotherapy for Stage 4 non-small cell lung cancer is currently re…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a recombinant EphB4-HSA fusion protein in combination with standard chemotherapy for advanced or metastatic solid t…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating nivolumab with radiation therapy, with or without ipilimumab, for brain metastases arising from non-smal…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update evaluating CIMAvax-EGF vaccine in combination with nivolumab and pembrolizumab for advanced or metasta…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer [Phase 2]
This entry describes a Phase 2 clinical trial evaluating proton beam radiation therapy after surgical resection for N2 non-small cell lung c…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer [Phase 1]
Phase 1 trial update for ceritinib and everolimus in patients with locally advanced or metastatic solid tumors, including non-small cell lun…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer [NA]
A clinical trial is evaluating a fasting-mimicking diet in combination with immunotherapy for stage IV non-small cell lung cancer and is cur…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab [Phase 1, Phase 2]
Clinical trial update for ARRY-614 in combination with nivolumab or nivolumab plus ipilimumab (Phase 1/2) currently active and not recruitin…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers [Phase 2]
A Phase 2 trial is evaluating Osimertinib alone or in combination with chemotherapy for EGFR-mutant metastatic non-small cell lung cancer an…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer [Phase 2]
A Phase 2 trial evaluating GEN1046 as a single agent or in combination with pembrolizumab for recurrent/metastatic non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer [Phase 1, Phase 2]
A clinical trial update on a Phase 1/2 study evaluating the combination of durvalumab, tremelimumab, and selumetinib in patients with recurr…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer [Phase 2]
This document reports an update on a Phase 2 trial evaluating telisotuzumab vedotin (ABBV-399) in patients with previously treated c-Met–pos…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946 [Phase 1, Phase 2]
Phase 1/2 open-label study evaluating the safety, tolerability, PK and anti-tumor activity of YH42946 in non-small cell lung cancer and othe…