Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: A Randomized Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC [Phase 2]
A randomized Phase II trial evaluates upfront stereotactic radiotherapy to all brain metastases followed by Ivonescimab plus chemotherapy ve…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: PALACE: Cemiplimab Trial According to ctDNA Levels [Phase 2]
Phase 2 PALACE trial assesses cemiplimab guided by circulating ctDNA levels in non-small cell lung cancer and related thoracic neoplasms; th…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Neoadjuvant Treatment With Atezolizumab and Atezolizumab as Maintenance for the Treatment of Stage III Non Small-Cell Lung Cancer (NSCLC) [Phase 2]
This Phase 2 trial examines neoadjuvant atezolizumab followed by maintenance therapy for stage III non-small cell lung cancer and is current…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: THE EFFECT OF CALISTHENIC EXERCISES ON FATIGUE AND EXERCISE ATTITUDES IN PATIENTS WITH LUNG CANCER [NA]
A clinical trial is evaluating whether calisthenic exercises can reduce fatigue and improve exercise attitudes in patients with non-small ce…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients [Phase 2]
Phase 2 clinical trial update investigating tumor-infiltrating lymphocyte (TIL) therapy for non-small cell lung cancer. The study is current…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation [Phase 1]
A Phase 1 study evaluating furmonertinib in NSCLC patients with EGFR exon 20 insertion mutations is ongoing; the trial is currently active b…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Ensartinib After Chemoradiotherapy in Stage III ALK-Mutated NSCLC [Phase 2]
Phase 2 clinical trial evaluating ensartinib after chemoradiotherapy in patients with stage III ALK-mutated non-small cell lung cancer; the …
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Study of ctDNA as Prognostic Factor on Resectable Stage IIIA NSCLC Patients Treated With Neoadjuvant Treatment
This clinical trial update describes a study investigating circulating tumor DNA as a prognostic factor in patients with resectable Stage II…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation [NA]
Massachusetts General Hospital describes using serial plasma NGS as a new efficacy metric to guide immunotherapy treatment discontinuation. …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Phase III Study of SHR-8068 Combined With Adebrelimab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 3]
A Phase III trial comparing SHR-8068 plus Adebrelimab and chemotherapy versus Tislelizumab plus chemotherapy for locally advanced or metasta…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Neoadjuvant SBRT and Tislelizumab (Immunotherapy) Plus Anlotinib for Resectable EGFR Wild-type NSCLC [Phase 2]
This is a Phase 2 trial evaluating neoadjuvant SBRT with tislelizumab and anlotinib for resectable EGFR wild-type non-small cell lung cancer…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Combination of Paclitaxel-bevacizumab ± Atezolizumab in Patients With Advanced NSCLC Progressing After Immunotherapy & Chemotherapy [Phase 2]
This is a Phase 2 clinical trial evaluating paclitaxel with bevacizumab, with or without atezolizumab, in patients with advanced non-small c…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Study of QL1706 in Combination With Chemotherapy in PD-L1-Negative Non-small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluating QL1706 in combination with chemotherapy for patients with PD-L1-negative non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients [Phase 3]
Phase 3 clinical trial evaluating early specialized cardiovascular intervention guided by impedance cardiography in locally advanced non-sma…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 study of Tolododekin Alfa (ANK-101) in combination with an anti-PD-1/PD-L1 antibody in adults with advanced non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Phase II Clinical Study of SHR2554 Tablets Combined With Other Anti-tumor Treatments in Non-small Cell Lung Cancer Subjects [Phase 2]
Phase II clinical trial of SHR2554 tablets in combination with other anti-tumor treatments for locally advanced or metastatic non-small cell…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer [Phase 1]
Phase 1 trial of DS8201a (trastuzumab deruxtecan) in combination with pembrolizumab for locally advanced/metastatic breast cancer or non-sma…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: ENCOrafenib With Binimetinib in bRAF NSCLC [Phase 2]
Phase 2 trial evaluating encorafenib plus binimetinib in non-small cell lung cancer with BRAF V600E mutation; current status is active but n…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Physical Activity Coaching After Surgery for Patients With Resectable Non-small Cell Lung Cancer [NA]
This clinical trial update notes that a study examining physical activity coaching after surgery for patients with resectable non-small cell…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy [Phase 3]
Phase 3 trial evaluating atezolizumab with carboplatin/paclitaxel in elderly patients with advanced non-small cell lung cancer; the study is…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TNG260 in combination with an anti-PD antibody in STK11-mutated solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Feasibility Testing of a Dyadic Exercise Program for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers [NA]
A clinical trial is evaluating the feasibility of a dyadic exercise program for patients undergoing thoracic radiotherapy and their family c…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01） [Phase 3]
This document provides an update on a Phase 3 clinical trial (SYNSTAR01) evaluating SYS6010 versus platinum-based chemotherapy in EGFR-mutat…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Pembrolizumab (SB27, EU Sourced Keytruda, and US Sourced Keytruda) in Subjects With Stage II-IIIA NSCLC Following Complete Resection and Adjuvant Platinum-based Chemotherapy [Phase 1]
Phase 1 trial comparing pharmacokinetics, efficacy, safety, and immunogenicity of the pembrolizumab biosimilar SB27 versus EU/US-sourced pem…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors [Phase 1, Phase 2]
Phase Ib/II clinical study evaluating HLX43 in combination with serplulimab for advanced/metastatic solid tumors is currently recruiting. Th…