Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of MT-4561 in Patients With Various Advanced Solid Tumors [Phase 1, Phase 2]
This trial update reports that MT-4561 is being studied in multiple advanced solid tumors across Phase 1/Phase 2 and is currently recruiting…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Phase Ib Study of GC101 in NSCLC [Phase 1]
This document reports a Phase Ib clinical trial evaluating GC101 in non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating immunotherapy or targeted therapy with or without stereotactic radiosurgery for brain metastases in patien…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Neoadjuvant Sunvozertinib in Stage II-IIIB Non-small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutation. [Phase 2]
This is a Phase 2 neoadjuvant trial of Sunvozertinib for potentially resectable EGFR exon 20 insertion non-small cell lung cancer (Stage II–…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Hyperprogression in PD-L1 ≥ 50% NSCLC: a Biomarker Guided Phase 2 Trial [Phase 2]
A biomarker-guided Phase 2 trial in non-small cell lung cancer evaluating hyperprogression in patients with PD-L1 expression ≥ 50%. The stud…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations [Phase 1, Phase 2]
Phase 1/2 study of Silevertinib (BDTX-1535) in glioblastoma and EGFR-mutant non-small cell lung cancer is currently active but not recruitin…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: A Phase 2 Randomized, Controlled Trial of QL1706 Plus Chemotherapy and Quad Shot for Driver Gene-negative Advanced Non-small Cell Lung Cancer. [Phase 2]
Phase 2 randomized trial assessing QL1706 plus chemotherapy and Quad Shot for driver gene-negative advanced non-small cell lung cancer; the …
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Impact of Circadian Rhythm on Immunotherapy [Phase 2]
Phase 2 trial evaluating the impact of circadian rhythm on immunotherapy in advanced/metastatic non-small cell lung cancer; currently recrui…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating first-line combination therapy with osimertinib and tegavivint for metastatic EGFR-mutant non-small cell…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: This Study is Comparing Morning vs Random Scheduling of Standard of Care Pembrolizumab Checkpoint Inhibitor Immunotherapy Infusions in Patients With Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial comparing morning versus random scheduling of standard-of-care pembrolizumab infusions for metastatic non-small cel…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating photon craniospinal irradiation for leptomeningeal metastases arising from breast cancer or non-small ce…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Shared Decision Making on Radiation Dose for Lung Malignancies [NA]
Clinical trial update indicates ongoing recruitment for a study on shared decision making regarding radiation dose in lung cancer patients, …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients [Phase 3]
This is an update on a Phase III trial evaluating SKB264 in EGFR-mutant non-small cell lung cancer; the study is currently active but not re…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study of SYS6010 Combined With Osimertinib Versus Osimertinib Alone as Neoadjuvant Therapy for Patients With EGFR Mutation-positive Resectable Non-squamous Non-small Cell Lung Cancer [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant study evaluating SYS6010 plus osimertinib versus osimertinib alone in EGFR-mutant…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Minimal Residual Disease in Solid Malignancies [NA]
This clinical trial update describes a study evaluating minimal residual disease in solid malignancies across several cancers, and it is cur…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial) [Phase 2]
A Phase 2 SWOG Lung-MAP trial is evaluating combinations of targeted therapies for advanced non-small cell lung cancer with EGFR and MET gen…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Exercise as a Tool to Improve Response to Immunotherapy in Non-small Cell Lung Cancer [NA]
This clinical trial aims to assess whether exercise can improve responses to immunotherapy in non-small cell lung cancer, with the study cur…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer [NA]
This clinical trial investigates smartphone-based remote symptom monitoring to improve adherence to postoperative rehabilitation exercises a…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating SKB264 in combination with Osimertinib versus Osimertinib alone in EGFR-mutant non-squamous non-small cell lung can…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the combination of binimetinib and pembrolizumab for advanced non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial) [Phase 2]
Phase 2 expanded Lung-MAP trial evaluating a MET-targeted therapy for advanced non-small cell lung cancer with MET gene amplification; recru…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer [Phase 2, Phase 3]
Lung-MAP is a master screening protocol for patients with previously treated non-small cell lung cancer, currently in Phase 2 and Phase 3 an…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Predictive Value of Exosomes in Pleural Effusion for Advanced Lung Cancer
This clinical trial update investigates whether exosomes from pleural effusion can serve as predictive biomarkers for outcomes in advanced n…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Neoadjuvant Chemo-immunotherapy for Stage III PD-L1 Positive Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial update announcing ongoing recruitment for neoadjuvant chemo-immunotherapy in stage III PD-L1 positive non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…