Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: A Trial of HRS-4508 in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial of HRS-4508 for locally advanced or metastatic non-small cell lung cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of INBRX-106 in combination with pembrolizumab for locally advanced or metastatic sol…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC Regimen [Phase 2]
A Phase II clinical trial evaluating radiotherapy followed by durvalumab and ceralasertib in stage III non-small cell lung cancer patients w…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Accelerating Lung Cancer Diagnosis Through Liquid Biopsy
This clinical trial update notes an active-not-recruiting study sponsored by University Health Network in Toronto, investigating liquid biop…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study [NA]
Pilot study evaluating acupuncture to enhance immunotherapy in advanced non-small cell lung cancer; the trial is currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Effects of Genomic Profiles on Thromboembolic Risk in Patients With Locally Advanced or Metastatic Non-small-cell Lung Cancer
This clinical trial update describes a study investigating how patients' genomic profiles influence thromboembolic risk in locally advanced …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity [Phase 2]
Phase 2 clinical trial investigating cabozantinib in RET fusion-positive advanced non-small cell lung cancer and in patients with ROS1, NTRK…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC [Phase 2]
Phase 2 clinical trial evaluating FDG-PET guided small-volume accelerated immuno-chemoradiotherapy for locally advanced, unresectable non-sm…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated [Phase 3]
A Phase 3 trial evaluating tepotinib versus standard treatment in adults with advanced MET exon 14-mutated non-small cell lung cancer that h…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Dupilumab_Metastatic NSCLC [Phase 1, Phase 2]
Clinical trial update indicates a Phase 1/Phase 2 study of dupilumab in metastatic non-small cell lung cancer is currently active but not re…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Prediction of Targeted Therapy Efficacy in EGFR-mutant Lung Cancer Patients Using AI-based Multimodal Data
A clinical trial is exploring AI-based multimodal data to predict efficacy of targeted therapies in EGFR-mutant non-small cell lung cancer, …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: ROSE for Improved Molecular Marker Testing Via EBUS [NA]
A Johns Hopkins clinical trial is evaluating ROSE-enabled molecular marker testing via EBUS for non-small cell lung cancer and is currently …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: HC010 in First-line PD-L1 Positive Advanced NSCLC Patients [Phase 2]
Phase 2 clinical trial HC010 is recruiting in first-line PD-L1 positive advanced non-small cell lung cancer patients.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors [Phase 1]
Clinical trial update for a Phase 1 study evaluating the safety and pharmacokinetics of ADU-1805 in adults with advanced solid tumors; the s…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies [Phase 4]
Phase 4 master-protocol trial evaluating systemic therapies in elderly patients with thoracic malignancies, including non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: A Phase 1 Study of LNCB74 in Advanced Solid Tumors [Phase 1]
Status update for a Phase 1 study of the investigational agent LNCB74 in patients with various advanced solid tumors, including ovarian, bre…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Stereotactic Body Radiotherapy With Sequential Iparomlimab and Tuvonralimab (QL1706) + Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Non-small-cell Lung Cancer in China (LUNG-Nanjing01): a Single-arm, Single-centre, Phase 2 Trial [Phase 2]
Phase 2, single-arm trial in China evaluating neoadjuvant stereotactic body radiotherapy with sequential iparomlimab and tuvonralimab (QL170…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is studying SHR-A1811 with Adebelimumab as neoadjuvant therapy for resectable HER2-altered non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase II clinical study evaluating safety, efficacy, and pharmacokinetics/pharmacodynamics of JSKN033 in patients with advanced non-small ce…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Phase 3 Study of Sunvozertinib Versus Placebo as Adjuvant Therapy in Patients With Early-Stage Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations or PACC Mutations After Radical Surgery [Phase 3]
Phase 3 study evaluating sunvozertinib versus placebo as adjuvant therapy in early-stage non-small cell lung cancer with EGFR exon 20 insert…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Cancer of the Lung And SeneScencE - Prospective Cohort 1 [NA]
Prospective cohort trial on non-small cell lung cancer led by Assistance Publique - Hôpitaux de Paris is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: TRIMPACT: Real-World First-Line Atezolizumab Use in Stage IV NSCLC With PD-L1 ≥50%
A real-world, first-line study (TRIMPACT) is currently recruiting to evaluate atezolizumab use in stage IV non-small cell lung cancer with P…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
This update describes a Phase 2 clinical trial evaluating HRS-4508 in combination with other antitumor therapies for locally advanced or met…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma [Phase 1, Phase 2]
Clinical trial update for VMD-928 as a monotherapy and in combination with pembrolizumab to treat TrkA overexpression-driven solid tumors or…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating hippocampal avoidance in craniospinal irradiation for leptomeningeal metastases from breast cancer or no…