Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Adaptive Adjuvant Sintilimab Therapy Guided by MRD (ADAPT Lung) [Phase 2]
An ongoing Phase 2 trial (ADAPT Lung) evaluating adaptive adjuvant sintilimab therapy guided by minimal residual disease in non-small cell l…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating PET-guided stereotactic body radiation therapy for oligoprogressive disease in non-small cell lung ca…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Validation of the TheraSure CNI-Monitor Under Immuno-checkpoint-therapy (Hereinafter: "Immunotherapy") in NSCLC in Palliative Therapy
This entry reports a trial validating the TheraSure CNI-Monitor in non-small cell lung cancer patients undergoing immunotherapy in palliativ…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: A Multi-centre Chart Review Study of Stage I-III Non-Small Cell Lung Cancer in China
This clinical trial update describes a planned multi-centre chart review study of stage I-III non-small cell lung cancer in China; recruitme…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer [Phase 1, Phase 2]
The document reports a Phase 1/Phase 2 clinical trial evaluating ZG005 in combination with Gecacitinib in patients with advanced non-small c…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Locally Advanced NSCLC Treated With Radiochemotherapy: Phase 2 Study on the Value of a Stereotactic Boost [Phase 2]
A Phase 2 study is evaluating radiochemotherapy with a stereotactic boost for locally advanced non-small cell lung cancer and is currently r…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
This clinical trial update describes the CCANED-CIPHER study, an ongoing investigation using AI-based transcriptomic profiling of platelets …
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
This clinical trial update from Ohio State University Comprehensive Cancer Center describes evaluating imaging and blood-based biomarkers to…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating a combination of low-dose radiation, SBRT, tislelizumab, and platinum-based chemotherapy for stage II…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA) [Phase 2]
Phase 2 trial evaluating adjuvant cisplatin-based chemotherapy plus concurrent atezolizumab in resected non-small cell lung cancer, with cir…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients [Phase 2]
A Phase 2 clinical trial evaluating lazertinib in treatment-naïve non-small cell lung cancer with activating EGFR mutations; the study is cu…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: The HER Project: HRD in EGFR-mutated NSCLC
An update on an ongoing clinical trial investigating homologous recombination deficiency in EGFR-mutated non-small cell lung cancer using a …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21) [Phase 2]
Phase II trial evaluating the combination of DZD9008 with AZD4205 in NSCLC patients with EGFR mutations who failed standard therapy is curre…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Sleeve Lobectomy Following Neoadjuvant Therapy in NSCLC
Clinical trial update notes sleeve lobectomy after neoadjuvant therapy for non-small cell lung cancer; study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR) [NA]
A clinical trial (NCT06524427) is recruiting to compare robot-assisted lobectomy versus video-assisted lobectomy for non-small cell lung can…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Ladarixin With Sotorasib in Advanced NSCLC [Phase 1]
A Phase 1 clinical trial update notes the combination of ladarixin with sotorasib for advanced non-small cell lung cancer with KRAS G12C mut…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Study for Evaluating the Safety and Feasibility of Fecal Microbiota Transplant in Stage II-III NSCLC Patients Using ICI Responders as Donors (MIGRANT) [Phase 2]
A Phase 2 clinical trial (MIGRANT) is evaluating the safety and feasibility of fecal microbiota transplant in stage II-III non-small cell lu…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Description of Neurocognitive and Psychiatric Disorders Associated With Targeted Therapies Used in the Treatment of Lung Cancers With ALK/ROS1 Fusion and Their Impact on Patients' Quality of Life: Construction of an Experimental Patient-researcher Collaborative Care and Research Pathway
This clinical trial update outlines a study examining neurocognitive and psychiatric side effects of ALK/ROS1-targeted therapies in metastat…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN2) [Phase 1]
A Phase 1 trial evaluating DZD6008, an oral EGFR inhibitor from Dizal Pharmaceuticals, in patients with advanced non-small cell lung cancer …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Bolstering Outcomes After Induction With Osimertinib Plus Chemotherapy Through Optimized Site-Directed Primary Tumor Therapy (BOOST Trial) [Phase 2]
Phase 2 trial evaluating Osimertinib plus chemotherapy with optimized site-directed primary tumor therapy to improve outcomes in non-small c…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC [Phase 2]
This is a Phase 2 neoadjuvant trial of SBRT followed by sintilimab plus chemotherapy for N3-positive locally advanced non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma
A clinical trial update describing validation of molecular diagnostic assays that detect cancer biomarkers in blood and primary tumors. The …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: The Construction and Clinical Application of an Integrated Perioperative Management System for Lung Cancer Based on Wearable Devices and Intelligent Platforms [NA]
This document reports on the development and planned clinical use of an integrated perioperative management system for lung cancer using wea…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With MET Abnormalities [Phase 2]
Phase II clinical trial of SKB571 as monotherapy for locally advanced or metastatic non-small cell lung cancer with MET abnormalities; the s…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform
An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…