Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors [Phase 1]
Phase 1 update on LY4066434, a pan-KRAS inhibitor, in KRAS-mutant solid tumors, including pancreatic ductal adenocarcinoma and non-small cel…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial [Phase 3]
A Phase 3 trial called INSIGHT is evaluating immunotherapy after surgery for people with early-stage non-small cell lung cancer who have no …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Multicenter, Non-interventional, Descriptive Study to Assess Assay Concordance of HER2 IHC Testing in Chinese Pan-tumor Patients
AstraZeneca is conducting a multicenter, non-interventional study in Chinese pan-tumor patients to assess concordance of HER2 IHC testing ac…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase I Study of [111In]-FPI-2107 in EGFR Mutation-positive NSCLC [Phase 1]
A Phase I clinical trial evaluating the radiolabeled compound [111In]-FPI-2107 in patients with EGFR mutation-positive non-small cell lung c…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors [Phase 1, Phase 2]
Verastem is evaluating the KRAS G12D-mutated cancer drug VS-7375 in a Phase 1/2 study across several solid tumors, including pancreatic duct…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Immune Signature Analysis of Disease Progression in Post Immunotherapy Lung Cancer Patients
This clinical trial update describes analysis of immune signatures associated with disease progression in patients with non-small cell lung …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: NSCLC Liquid Biopsies and Exhaled VOC
An ongoing clinical trial at St. Joseph's Healthcare Hamilton is evaluating liquid biopsy approaches (circulating tumor DNA) and exhaled vol…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: CHOICE:Decision Factor of EGFR-TKI in Chinese IV NSCLC
A ClinicalTrials.gov entry sponsored by AstraZeneca describes the CHOICE study evaluating decision factors for EGFR-TKI therapy in Chinese p…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients [Phase 1, Phase 2]
Clinical trial update for TNG462 in combination therapy for pancreatic ductal adenocarcinoma and non-small cell lung cancer, currently recru…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) [Phase 3]
This is a Phase 3 randomized trial evaluating Intismeran Autogene (V940) plus pembrolizumab versus placebo plus pembrolizumab in non-small c…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: An Observational Study to Assess the Effectiveness and Safety of a Cemiplimab in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) in Routine Clinical Practice Settings in Europe
An observational study to evaluate the effectiveness and safety of cemiplimab in adults with advanced non-small cell lung cancer in routine …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Efficacy and Safety of SKB264 Plus Anlotinib in EGFR-TKI-Resistant Advanced NSCLC With Liver Metastasis [Phase 2]
A Phase 2 clinical trial evaluating the combination of SKB264 and Anlotinib for EGFR-TKI-resistant advanced non-small cell lung cancer with …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC) [Phase 3]
This is a Phase 3 study comparing Pfizer investigational PF-08046054/SGN-PDL1V to docetaxel in adults with previously treated PD-L1 positive…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC [Phase 2]
A Phase 2 neoadjuvant trial evaluating IBI308 with bevacizumab plus pemetrexed and carboplatin followed by surgery in unresectable stage III…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Overcoming Resistance to Immunotherapy Combining Gemcitabine With Ivonescimab in Advanced NSCLC [Phase 2]
Phase 2 clinical trial investigating gemcitabine plus ivonescimab for advanced non-small cell lung cancer is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Iparomlimab and Tuvonralimab Injection Combined With SBRT in Patients With Early-Stage Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial investigating the combination of iparomlimab and tuvonralimab with stereotactic body radiotherapy for early-stage n…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations. [Phase 2]
A Phase 2 neoadjuvant umbrella trial for patients with unresectable stage III non-small cell lung cancer and rare mutations is currently rec…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors [Phase 1]
Phase 1 trial evaluating [225Ac]Ac-AKY-1189 for solid tumors is currently recruiting, including urothelial carcinoma of the bladder and trip…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC [Phase 2]
Phase 2 clinical trial evaluating Visugromab with nivolumab, with or without docetaxel, for second-line metastatic non-squamous non-small ce…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Barriers and Facilitators of Persistence With Adjuvant Osimertinib
Clinical trial update examining barriers and facilitators to persistence with adjuvant osimertinib in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial in resected Stage II-III KRAS G12C-positive non-small cell lung cancer compares Divarasib with investigator's choice of immu…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer [Phase 3]
This document announces a Phase 3 clinical trial comparing ABP 234 to pembrolizumab (Keytruda) in patients with advanced or metastatic non-s…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating CIMAvax-EGF in combination with a KRAS G12C inhibitor for advanced KRAS G12C-mutated non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial of S241656 in RAS/MAPK mutation-positive malignancies is currently recruiting. The study targets non-small cell lun…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies [Phase 1]
Phase 1 study to assess safety and preliminary efficacy of KQB368 as monotherapy in participants with advanced solid malignancies; the trial…