Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: First in Human Study of TUB-030 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
First-in-human study of TUB-030 is underway in patients with advanced solid tumors, including head and neck squamous cell carcinoma, small c…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Study of Oral MRT-2359 in Selected Cancer Patients [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 trial evaluating MRT-2359 in multiple cancer indications; trial is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: OSIREAL - Osimertinib RWE on EGFRm NSCLC in Spain
This entry reports the OSIREAL real-world evidence trial of Osimertinib for EGFR-mutant non-small cell lung cancer in Spain, sponsored by As…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers [Phase 1]
Nuvectis Pharma reports a Phase 1 clinical trial of NXP-900 in subjects with advanced cancers is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Prospective Data Collection Initiative on Thoracic Malignancies
A prospective data collection initiative on thoracic malignancies sponsored by the Dutch Society of Physicians for Pulmonology and Tuberculo…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Engagement of Veterans With Lung Cancer [NA]
A clinical trial update indicates the study sponsored by Palo Alto Veterans Institute for Research is currently recruiting veterans with var…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease [Phase 2]
This Phase 2 trial update describes evaluating BIO 300 with thoracic radiation therapy in people with non-small cell lung cancer and interst…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC [Phase 1]
A Phase 1 clinical trial is evaluating intrathecal pemetrexed in combination with bevacizumab for leptomeningeal metastases in non-small cel…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Repositioning Immunotherapy in VetArans With Lung Cancer [Phase 2]
Phase 2 clinical trial update noting recruitment for a repositioned immunotherapy approach in veterans with non-small cell lung cancer. The …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Trial of AK112 (PD1/VEGF Bispecific) in Combination With Chemotherapy in Patients With NSCLC [Phase 2]
Phase 2 trial of AK112, a PD1/VEGF bispecific, in combination with chemotherapy for non-small cell lung cancer; currently active but not rec…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating datopotamab deruxtecan (Dato-DXd) with or without osimertinib vs platinum-based chemotherapy in EGFR-mutat…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping [Phase 2]
Phase 2 trial exploring brigatinib in ALK-positive non-small cell lung cancer with deep phenotyping.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Next Generation Sequencing Method for the Detection of EGFR Gene Mutations in the Plasma of Patients With Lung Cancer [NA]
A clinical trial entry describing a study that evaluates a next-generation sequencing method for detecting EGFR gene mutations in the plasma…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update for HMBD-501 evaluating safety, tolerability, pharmacokinetics, and preliminary efficacy in HER3-e…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Single-Fraction Pulmonary Ablative Radiotherapy Outcomes and Quality-of-life Workup
This clinical trial update describes NCT07441941, evaluating single-fraction pulmonary ablative radiotherapy for oligometastatic lung tumors…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study evaluating adverse events and efficacy of Telisotuzumab Adizutecan in combination with a …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease [Phase 2]
A Phase 2 clinical trial is evaluating whether adding stereotactic body radiotherapy to standard of care improves outcomes for patients with…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: 3D Virtual Resection for Predicting Lung Function in VATS
A clinical trial from National Taiwan University Hospital is evaluating 3D virtual resection to predict postoperative lung function after vi…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors [Phase 1]
This clinical trial update describes a Phase 1 study of CGT4255, a selective ERBB2 inhibitor, in adults with ERBB2-altered advanced solid tu…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer [Phase 1]
Phase 1 clinical trial evaluating the combination of vismodegib and atezolizumab for recurrent or metastatic non-small cell lung cancer; the…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1) [Phase 1]
A multinational Phase 1 trial evaluating the oral EGFR inhibitor DZD6008 in patients with advanced EGFR-mutant Non-Small Cell Lung Cancer, c…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Induction Chemotherapy and Toripalimab Followed by Chemoradiotherapy for Large-volume Local Advanced NSCLC [Phase 2]
A Phase 2 study investigates induction chemotherapy plus toripalimab followed by chemoradiotherapy for large-volume local advanced non-small…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer [Phase 1]
This Phase 1 trial is evaluating a Fluorine-18 labeled AlphaVbeta6-binding peptide as a PET imaging agent for metastatic non-small cell lung…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial is investigating whole-body quantification of HER2 with 89Zr-trastuzumab PET/CT to assess tracer accumulation in HE…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Promoting Immunotherapy Efficacy With Low-Dose Liver RT [NA]
A clinical trial evaluating whether low-dose liver radiotherapy can boost immunotherapy efficacy in non-small cell lung cancer, melanoma, an…