Non-small Cell Lung Cancer
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase Ib Study of RC148 as Monotherapy or Combination for Locally Advanced or Metastatic NSCLC [Phase 1]
This document describes a Phase Ib trial of RC148 as a monotherapy or in combination for locally advanced or metastatic non-small cell lung …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor
A clinical trial update describes a PD-L1–targeting peptide probe for PET imaging of solid tumors, with not-yet-recruiting status and condit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy [NA]
This clinical trial update indicates ongoing recruitment for a study evaluating practical geriatric assessment in older adults with non-smal…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: U3-1402 in Metastatic or Unresectable Non-Small Cell Lung Cancer [Phase 1]
Phase 1 clinical trial update for U3-1402 in patients with metastatic or unresectable non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer [Phase 1]
Phase 1 trial evaluating ipilimumab and nivolumab in combination with radiation therapy for stage II-III non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Early Feasibility Study (EFS) of the 'CAROL' for Treatment of Lung Cancer Stage 1 [NA]
An early feasibility study of the CAROL treatment for stage 1 non-small cell lung cancer is currently recruiting, sponsored by Tau Medical A…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: An Exploratory Study of QL1706 Plus Chemotherapy in Perioperative NSCLC [NA]
Clinical trial update indicating an exploratory study of QL1706 plus chemotherapy in perioperative non-small cell lung cancer, currently rec…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Phase II Trial of Lung Chemoemobolization [Phase 2]
Phase II trial of lung chemoembolization is currently recruiting. The listed indications include non-small cell lung cancer, mediastinal and…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Observational, Prospective, Multi-centric Study Exploring HER2 Mutations Incidence and Therapeutic Management in aNSCLC
A multicenter observational prospective study in advanced non-small cell lung cancer to determine the incidence of HER2 mutations and assess…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: SYS6010 Versus Docetaxel for Previously Treated EGFR Wild-type NSCLC: Phase Ⅲ [Phase 3]
A Phase 3 clinical trial comparing SYS6010 to Docetaxel for previously treated EGFR wild-type non-small cell lung cancer; the study is not y…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Phase 3 Clinical Study of AK112 for NSCLC Patients [Phase 3]
Phase 3 trial update for AK112 in non-small cell lung cancer; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial evaluating selpercatinib as adjuvant therapy after surgery or radiation in patients with non-small cell lung cancer; the stu…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients Undergoing Chemoradiation [Phase 2]
Phase 2 clinical trial protocol evaluating pneumonitis prevention using pentoxifylline and alpha-tocopherol in stage III non-small cell lung…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: ctDNA-Guided CURB for OPD mNSCLC on TKI (CURB-TKI) [Phase 2]
Phase 2 clinical trial evaluating a ctDNA-guided CURB strategy for oligo-progressive metastatic non-small cell lung cancer in patients on ty…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy [Phase 2]
A Phase 2 trial is evaluating durvalumab in combination with radiation therapy for early-stage non-small cell lung cancer. The study is curr…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC) [Phase 2]
This is an update on a Phase 2 trial evaluating five years of adjuvant osimertinib in completely resected EGFR-mutant non-small cell lung ca…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 [Phase 2]
A Phase 2 clinical trial is evaluating perioperative cemiplimab for patients with resectable non-small cell lung cancer and high PD-L1 expre…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer [Phase 1]
Phase 1 clinical trial evaluating the combination of osimertinib and carotuximab in advanced EGFR-mutated non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: 18F-FDG PET/CT Radiomics Models for Precision Diagnosis and Prognosis in NSCLC
This entry reports an active but not recruiting clinical trial evaluating 18F-FDG PET/CT radiomics for precision diagnosis and prognosis in …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Palliative Thoracic ImmunoRT
Clinical trial update for the Palliative Thoracic ImmunoRT study indicates the trial in non-small cell lung cancer is currently active but n…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC [Phase 1, Phase 2]
First-in-human Phase 1/2 trial of the NaPi2b-targeted antibody-drug conjugate TUB-040 assessing safety, PK, and preliminary efficacy in pati…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Phase 3 Study of IN10018 in Combination With D-1553 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation [Phase 3]
A Phase 3 clinical trial is evaluating IN10018 in combination with D-1553 versus standard therapy as first-line treatment for non-squamous n…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: LM103 in Phase IIa Clinical Trial for Adjuvant Treatment in Patients With Non-small Cell Lung Cancer [Phase 2]
A Phase IIa adjuvant trial of LM103 for non-small cell lung cancer is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities [Phase 1, Phase 2]
A Phase 1/2 clinical trial of TAS0953/HM06, a RET inhibitor, in adults with RET-altered advanced solid tumors including non-small cell lung …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer
A clinical trial update describing a prospective external control cohort in newly diagnosed advanced or metastatic EGFR-mutant non-small cel…