Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Survey of Brigatinib Used To Treat People With Non-Small Cell Lung Cancer
Takeda-sponsored clinical trial evaluating brigatinib for non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Multi-center, Non-interventional, Prospective Study of Durvalumab in Unresectable Locally Advanced NSCLC in Routine Clinical Practice in Russia
A multi-center, non-interventional prospective study evaluating durvalumab in unresectable locally advanced non-small cell lung cancer in ro…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A clinical trial is evaluating benefits and harms of cannabis/cannabinoid use among cancer patients treated in community oncology clinics; r…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Integrated Genomics in Oncogene-driven NSCLC With Acquired Resistance
A clinical trial update on an integrated genomics approach in oncogene-driven non-small cell lung cancer with acquired resistance, currently…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Study of Novel Treatment Combinations in Patients With Lung Cancer [Phase 2]
A Phase 2 clinical trial sponsored by Gilead Sciences is evaluating novel treatment combinations in patients with non-small cell lung cancer…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI Progression [Phase 2]
Phase 2 clinical trial evaluating limertinib in combination with carboplatin and etoposide for EGFR-mutant non-small cell lung cancer with t…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer. [Phase 3]
A Phase 3 trial evaluating adding Durvalumab after chemotherapy and in combination with surgery for early-stage operable non-small cell lung…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Phase II Neoadjuvant Study of Garsorasib Followed by Ivonescimab Plus Chemotherapy in Resectable Stage IIA-IIIB KRAS G12C-Mutant NSCLC (GIVEN Study) [Phase 2]
Phase II neoadjuvant trial exploring Garsorasib followed by Ivonescimab plus chemotherapy in resectable stage IIA-IIIB KRAS G12C-mutant non-…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Experiences w/ & Attitudes Towards Immune Chckpt Inhibitors in NSCLC Patients Single Center Survey Based Study
This document describes a single-center survey of NSCLC patients assessing experiences with and attitudes toward immune checkpoint inhibitor…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer.
A feasibility study sponsored by Origin Sciences is recruiting to investigate rectal mucus in aero-digestive tract cancers, including Non-Sm…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A) [Phase 1, Phase 2]
Clinical trial update for MK-3475-01A/KEYMAKER-U01A evaluating pembrolizumab with or without chemotherapy in treatment-naïve Stage IV non-sm…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating durvalumab plus tremelimumab in combination with chemotherapy for HIV-infected patients with non-small cel…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: SYS6090 Combination Therapy in Advanced Lung Cancer [Phase 1, Phase 2]
Clinical trial update for SYS6090 combination therapy in advanced lung cancer, covering Phase 1 and Phase 2 studies; currently not yet recru…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene) [Phase 1]
Phase 1 study Beamion LUNG-1 evaluating multiple doses of Zongertinib in adults with advanced cancers harboring HER2 gene alterations, inclu…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China [Phase 1, Phase 2]
Allist Pharmaceuticals is conducting a Phase 1/2 clinical trial of JAB-21822 in adults with advanced KRAS p.G12C-mutant solid tumors in Chin…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 study at Virginia Commonwealth University evaluating reduced-dose chemotherapy plus anti-PD-1 therapy as first-line treatment for ol…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene. [Phase 1]
Phase 1 clinical trial evaluating PF-07985045 alone or with other anti-cancer therapies in adults with advanced solid tumors bearing gene al…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Clinical Trial on the Outcomes of Comprehensive Enhanced Prophylaxis Management (CEPM) in Chinese Patients With EGFR-Mutated Advanced NSCLC Receiving Amivantamab-Based Regimens [Phase 4]
This entry describes a Phase 4 clinical trial evaluating Comprehensive Enhanced Prophylaxis Management (CEPM) in Chinese patients with EGFR-…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of Biological, Genetic, and Constitutional Factors and Non-invasive Monitoring to Assess Personal Cancer Risks
This clinical trial investigates how biological, genetic, and constitutional factors, plus non-invasive monitoring, can help assess individu…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer [Phase 2]
A Phase 2 trial is investigating the combination of SX-682 with atezolizumab for advanced, metastatic, or recurrent non-small cell lung canc…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is testing dual-target CAR-NK cell therapy directed against MSLN, EGFR, or HER2 in patients with advanced n…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) [Phase 1, Phase 2]
PMV Pharmaceuticals is evaluating PC14586 in a Phase 1/2 trial for advanced solid tumors harboring the TP53 Y220C mutation. The study is cur…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Anti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCLC [Phase 2]
A Phase 2 trial is evaluating anti-PD-1 re-challenge after immune priming with ipilimumab and radiotherapy in advanced non-small cell lung c…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors [Phase 1]
A Phase 1 study evaluating Zanzalintinib in combination with immuno-oncology agents in patients with various solid tumors; recruitment is on…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
A Mayo Clinic-sponsored phase 1/2 trial evaluating a personalized neoantigen peptide-based vaccine in combination with pembrolizumab for adv…