Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
Prospective non-interventional trial evaluating outcomes for EGFR-mutated non-small cell lung cancer patients treated with osimertinib with …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Sacituzumab Tirumotecan Combined With Toripalimab for Resectable Stage II-IIIB NSCLC [Phase 2]
A Phase 2 clinical trial is evaluating sacituzumab govitecan in combination with toripalimab for resectable stage II-IIIB non-small cell lun…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study on the Efficacy and Safety of JSKN016 as Neoadjuvant Therapy in Resectable Stage II-III Non-small Cell Lung Cancer Patients [Phase 2]
Phase 2 trial entry for JSKN016 as neoadjuvant therapy in resectable stage II-III non-small cell lung cancer; currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC [Phase 3]
A global Phase III trial is evaluating Rilvegostomig or Pembrolizumab plus chemotherapy as first-line treatment for metastatic non-squamous …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating Ubamatamab with and without REGN7075 in adults with advanced or metastatic non-small cell lung cancer; currently re…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Retrospective Real-World Study Based on RATIONALE-307
A clinical-trial update announcing a retrospective real-world study based on RATIONALE-307 for advanced non-small cell lung cancer. The stud…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance [Phase 2]
A Phase 2 clinical trial evaluating ASP3082 in patients with metastatic or locally advanced non-small cell lung cancer and pancreatic ductal…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TILs Therapy for Multiple Primary Early-Stage NSCLC [EARLY_Phase 1]
Trial update for TILs therapy targeting multiple primary early-stage non-small cell lung cancer, currently in early phase 1 and not yet recr…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TILs Plus Third-Generation EGFR-TKI Therapy for TKI-Resistant NSCLC [EARLY_Phase 1]
An early-phase (Phase 1) trial is evaluating the combination of tumor-infiltrating lymphocytes (TILs) with a third-generation EGFR-TKI for p…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2, Phase 3]
Clinical trial update on magnesium supplementation for patients with advanced non-small cell lung cancer, a Phase 2/Phase 3 study that is no…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07) [Phase 3]
Phase 3 clinical trial update for first-line metastatic non-small cell lung cancer evaluating datopotamab deruxtecan with pembrolizumab, wit…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients [Phase 2]
A Phase 2 study is evaluating the combination of a PD-1 inhibitor (Sintilimab) with chemotherapy and adaptive radiotherapy for stage III non…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC [Phase 3]
A Phase III trial evaluating Envafolimab plus chemotherapy versus placebo plus chemotherapy in resectable stage III non-small cell lung canc…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Fulzerasib Sequential Sintilimab Plus Platinum-Doublet Neoadjuvant Therapy for Resectable KRAS G12C-Mutant NSCLC [Phase 2]
Reports a Phase 2 clinical trial evaluating Fulzerasib sequential with Sintilimab and platinum-doublet chemotherapy as neoadjuvant therapy f…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC [Phase 2]
A Phase 2 clinical trial is evaluating high-dose intravenous ascorbate added to chemotherapy and radiation therapy for non-small cell lung c…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Study of Sotorasib in People With Non-Small Cell Lung Cancer [Phase 2]
This clinical trial update reports that a Phase 2 study of sotorasib for non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC [Phase 1]
A Phase 1 clinical trial update for EPI-326 in EGFR-mutant non-small cell lung cancer and head and neck squamous cell carcinoma; the study i…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors [Phase 1, Phase 2]
A Phase Ib/II trial is evaluating the combination of Envafolimab (PD-L1 inhibitor) and lenvatinib in patients with solid tumors, including n…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Osimertinib Plus Capivasertib in NSCLC With PIK3CA/AKT1/PTEN Alterations Following Prior 1L Osimertinib [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of osimertinib and capivasertib in patients with advanced non-small cell lung cancer h…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: SHR-A1811 + AK112 in HER2-Altered Advanced/Metastatic NSCLC [Phase 2]
This document details a Phase 2 clinical trial of SHR-A1811 plus AK112 in HER2-altered advanced/metastatic non-small cell lung cancer, which…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC [Phase 1, Phase 2]
Clinical trial update for AZD2936, a bispecific anti-TIGIT/anti-PD-1 antibody, in participants with advanced or metastatic non-small cell lu…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Phase II Clinical Trial of SHR-1826 for Non-Small Cell Lung Cancer [Phase 2]
Phase II clinical trial update for SHR-1826 in non-small cell lung cancer; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC [Phase 2]
A Phase 2 clinical trial evaluating intrathecal pemetrexed for leptomeningeal metastasis in EGFR-mutant non-small cell lung cancer is curren…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC [Phase 3]
A Phase 3 trial of neladalkib (NVL-655) for tyrosine kinase inhibitor–naive patients with advanced ALK-positive non-small cell lung cancer i…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating a T cell receptor–based immunotherapy for patients with metastatic non-small cell lung cancer is current…