Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Global Phase III trial evaluating Rilvegostomig or pembrolizumab plus chemotherapy as first-line treatment for metastatic squamous non-small…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer [NA]
A clinical trial is planned to evaluate a multimodal outpatient supervised physical activity program designed to improve chemotherapy tolera…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer [Phase 1]
A Phase 1 trial from Emory University is evaluating the combination of MRX-2843 and osimertinib in adults with advanced EGFR-mutant non-smal…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer [Phase 1]
This Clinical Trials Update describes a Phase 1 study of an Fc-engineered anti-CTLA-4 monoclonal antibody by Agenus in patients with advance…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations [Phase 3]
Takeda's TAK-788 is being studied as a first-line treatment for advanced NSCLC with EGFR exon 20 insertion mutations in a Phase 3 trial agai…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS [Phase 2]
A Phase 2 trial compares durvalumab plus tremelimumab with chemotherapy against pembrolizumab plus chemotherapy in metastatic non-squamous n…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Immune and Genomic Markers in ALK+ NSCLC
A Massachusetts General Hospital-led clinical trial on immune and genomic markers in ALK-positive non-small cell lung cancer is currently ac…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of RAS(ON) inhibitors in combination with Ivonescimab is currently recruiting in patients with solid tumors, including non…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Multimodal Nutritional and Sarcopenia Assessment for Risk Stratification in Lung Cancer Surgery
A clinical trial from Ondokuz Mayıs University is evaluating multimodal nutritional assessment and sarcopenia for risk stratification in pat…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Crizotinib Continuation Clinical Study [Phase 4]
A Phase 4 continuation study of crizotinib sponsored by Pfizer is currently active but not recruiting. The study investigates crizotinib in …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors [Phase 1]
Phase 1 trial update on the safety of RAD301 in healthy volunteers and patients with pancreatic ductal adenocarcinoma or other solid tumors;…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating psilocybin-assisted therapy for major depressive disorder in patients with non-small cell lung cancer. The…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of JSKN016 Combination Therapy in Subjects With NSCLC [Phase 1]
Phase 1 clinical trial evaluating JSKN016 in combination therapy for advanced non-small cell lung cancer; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Phase 2 Study of Fingolimod in Lung Cancers [Phase 2]
Phase 2 clinical trial evaluating Fingolimod in non-small cell lung cancer and small-cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue [NA]
A Memorial Sloan Kettering Cancer Center trial evaluating radiation therapy for solid tumors that have metastasized to soft tissue. The stud…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Platform Study in Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
A platform trial in advanced or metastatic non-small cell lung cancer is currently recruiting for Phase 1 and Phase 2 cohorts sponsored by A…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers [Phase 1]
Phase 1 trial update for IOA-244, a PI3Kδ inhibitor, being studied in metastatic cancers with status currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: NIS to Examine the Effectiveness of TDC in Patients With Metastatic Non-squamous NSCLC and High-risk Genetic Alterations
This clinical trial update describes a non-interventional study to evaluate the effectiveness of TDC in patients with metastatic non-small c…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Phase 1B Trial of Intratumoral Cisplatin for Stage IV Lung Cancer [Phase 1]
Phase 1B trial of intratumoral cisplatin for stage IV non-small cell lung cancer is not yet recruiting. It represents early-phase exploratio…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors [Phase 1]
A Phase 1 study is evaluating tolerability, safety, and pharmacokinetics of AST-201 in patients with GPC3-positive advanced solid tumors; th…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1/2 studies of the radiopharmaceutical 177Lu-BetaBart. The trial is evaluating its use in…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 clinical trial is evaluating targeted radiation therapy for non-small cell lung cancer and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Efficacy of OBX-115 in Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update indicates OBX-115 is being studied in advanced solid tumors in Phase 1 and Phase 2, with recruitment ongoing for ind…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance [NA]
Massachusetts General Hospital reports an update on the Transitions Project, a study to support adults moving from cancer treatment to surve…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 trial evaluating HWK-007, a PTK7-directed antibody-drug conjugate, for advanced solid tumors; the study is currently recruiting.