Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Efficacy and Safety of Sacituzumab Tirumotecan (SKB264) in Combination With Toripalimab in Patients With Initially Unresectable Stage III NSCLC [Phase 2]
Phase 2 clinical trial evaluating sacituzumab tirumotecan (SKB264) in combination with toripalimab for initially unresectable stage III non-…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations [Phase 3]
This is a Phase 3 study evaluating trastuzumab deruxtecan as a first-line treatment for unresectable, locally advanced or metastatic non-sma…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial [Phase 3]
A Phase 3 trial comparing proton craniospinal radiation therapy to usual radiation therapy for leptomeningeal metastasis is currently recrui…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the combination of carfilzomib and sotorasib for KRAS G12C-mutated advanced or metastatic non-small cell lung cance…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours [Phase 1]
Phase 1 trial assessing safety and pharmacokinetics of DO-2 in adults with advanced solid tumors, including non-small cell lung cancer and h…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 trial is evaluating high-dose, targeted radiation added to standard therapy for locally advanced, inoperable non-small cell lung c…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations [Phase 1]
Phase 1 study to evaluate ALTA3263 in adults with KRAS-mutant advanced solid tumors, including pancreatic ductal adenocarcinoma, non-small c…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Real-World Data on the Treatment of Lung Cancer Patients With the Immune-Checkpoint Inhibitor Tislelizumab
A clinical-trial update presenting real-world data on using the immune-checkpoint inhibitor tislelizumab to treat lung cancer, with recruiti…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain [Phase 3]
Phase 3 trial comparing longer-duration radiation therapy versus standard radiation therapy for patients with cancer that has spread to the …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 study evaluating multiple therapies in biomarker-selected participants with resectable stage IB-III non-small cell lung cancer; curr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment [Phase 2]
A Phase 2 clinical trial is evaluating the safety and efficacy of serplulimab plus chemotherapy in small-cell lung cancer that has transform…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial update for atezolizumab in chemotherapy-naïve patients with stage IV non-small cell lung cancer expressing high PD-L1…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: FL-261 Imaging for Cancer Diagnosis and Staging
A clinical trial named FL-261 for imaging-based cancer diagnosis and staging is currently recruiting, studying its use across multiple cance…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
A Phase 1b/2 platform study investigating select immunotherapy combinations in participants with advanced non-small cell lung cancer; the tr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Oral Pooled Fecal Microbiotherapy (MaaT033) Concomitant to Cemiplimab Versus Best Investigator's Choice in Patients With Resistance to Treatment Due to Antibiotics Uptake With Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial in advanced non-small cell lung cancer evaluating MaaT033 fecal microbiotherapy given with cemiplimab versus investig…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. [Phase 2]
A Phase 2 trial evaluating Zipalertinib in advanced or metastatic non-small cell lung cancer with EGFR exon 20 insertion or other uncommon E…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: MDT-Based Umbrella Decision Model for Geriatric Lung Cancer Patients [NA]
Clinical trial update about an MDT-based umbrella decision model for geriatric lung cancer patients; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for IDE892 evaluating monotherapy and combination in MTAP-deleted advanced solid tumors. The study is currentl…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: DK222 Study at Hopkins [Phase 1]
This document provides a status update on the Phase 1 DK222 study at Johns Hopkins, which is currently recruiting. The trial targets non-sma…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of ZM008, an anti-LLT1 antibody, given as a single agent and then in combination with toripalimab in patients with ad…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Trial Comparing Systemic Therapy Alone and With Local Ablative Treatment for Stage IV NSCL Cancer Patients [NA]
A clinical trial evaluating whether adding local ablative treatment to systemic therapy improves outcomes for patients with stage IV non-sma…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients With EGFR-mutant, Locally Advanced or Metastatic/Recurrent Non-Small Cell Lung Cancer (INSTAR Study) [Phase 2]
Phase 2 clinical trial entry (INSTAR) evaluating amivantamab in combination with lazertinib or with chemotherapy in EGFR-mutant locally adva…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) [NA]
A clinical trial comparing singing training to usual care 6-18 months after surgical resection for non-small cell lung cancer. It is current…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer [Phase 3]
A Phase 3 clinical trial is assessing whether immunonutrition can reduce acute esophagitis in patients with lung cancer undergoing thoracic …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for VT3989 in adults with metastatic solid tumors, including mesothelioma and non-small cell lung cancer, currently re…