Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) [Phase 3]
KRYSTAL-4 is a Phase 3 trial evaluating adagrasib plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemotherapy in …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) [Phase 3]
Phase 3 trial evaluating adjuvant Intismeran (V940) with or without pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A) in hig…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
This clinical trial compares surgery versus stereotactic body radiation therapy for stage I non-small cell lung cancer, and the study is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC [Phase 2]
This clinical trial update describes a Phase 2 study of Atezolizumab with or without Tiragolumab for unresectable stage III non-small cell l…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Confocal Laser Endomicroscopy VERification [NA]
A clinical trial at Amsterdam University Medical Centers is investigating confocal laser endomicroscopy verification for lung cancer; the st…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) [Phase 1, Phase 2]
Genmab is conducting a Phase 1/2 clinical trial of Rinatabart Sesutecan for multiple advanced solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial update describing a study comparing treatment given before versus after surgery in patients with resectable stage II …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS) [Phase 1]
Phase 1 study of ADP-A2M4CD8 as monotherapy or in combination with nivolumab or pembrolizumab in HLA-A2+ patients with MAGE-A4-positive tumo…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for PF-08046052/SGN-EGFRd2 in advanced solid tumors, including colorectal cancer, non-small cell lung cancer, …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC (MTAPESTRY 201) [Phase 2]
This update covers a Phase 2 study (MTAPESTRY 201) of Anvumetostat in MTAP-deleted advanced non-small cell lung cancer, and the trial is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors [Phase 1]
Pfizer's Phase 1 study PF-08046876 is recruiting adults with various advanced solid tumors to evaluate safety and dosing. The trial includes…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors [Phase 1]
FT836 is being studied in a Phase 1 trial for advanced solid tumors, administered with or without chemotherapy and/or monoclonal antibodies.…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Adaptive Hypofractionated Radiotherapy for Locally Advanced NSCLC Based on Dynamic Enhanced MRI [Phase 3]
Phase 3 clinical trial update evaluating adaptive hypofractionated radiotherapy guided by dynamic enhanced MRI for locally advanced non-smal…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment [Phase 3]
An active Phase 3 trial is evaluating Savolitinib in combination with Osimertinib versus platinum-based chemotherapy in patients with non-sm…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases [NA]
Clinical trial update on a Gallium-68 labeled PSMA PET/CT tracer being studied to differentiate radiation necrosis from tumor progression in…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy
This clinical trial update reports real-world outcomes for ALK-positive early-stage non-small cell lung cancer patients treated with adjuvan…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study [Phase 2]
This clinical trial update reports on a Phase 2 NORTHSTAR study evaluating osimertinib in combination with surgery and radiation therapy for…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 1]
An update on a Phase 1b trial evaluating datopotamab deruxtecan (Dato-DXd) in combination with immunotherapy, with or without carboplatin, f…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients [Phase 2]
Ongoing Phase 2 neoadjuvant trial evaluating cemiplimab for resectable non-small cell lung cancer, hepatocellular carcinoma, and head and ne…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201) [Phase 3]
A Phase 3 clinical trial comparing Pumitamig to Durvalumab after concurrent chemoradiation in unresectable stage III non-small cell lung can…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer [Phase 1]
Phase 1 clinical trial evaluating autologous T-cells engineered to target KRAS mutations in combination with a KRAS-directed vaccine for met…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy [NA]
A clinical trial update comparing single-dose versus multiple-dose radiation in cancer patients with brain metastases who are receiving immu…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung Cancer [Phase 2]
This clinical trial update indicates a Phase 2 study evaluating defactinib, avutometinib, and nivolumab for anti-PD-1 refractory LKB1-mutant…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating NBTXR3 with radiation therapy alone for locally advanced non-small cell lung cancer. The stud…