Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer [Phase 1]
This update describes a Phase 1 study of amivantamab, a bispecific EGFR and cMet antibody, in participants with advanced non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib [Phase 2]
Phase 2 trial update describes enhanced dermatologic care to reduce rash and paronychia in patients with epidermal growth factor receptor-mu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain [Phase 2]
This is a Phase 2 clinical trial evaluating stereotactic radiosurgery with standard treatment for non-small cell lung cancer that has spread…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 clinical trial evaluating amivantamab in combination with lazertinib or with platinum-based chemotherapy for EGFR-mutated locally ad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be Treated With Surgery
Hoffmann-La Roche is sponsoring a study in China for patients with non-small cell lung cancer that cannot be treated surgically; the trial i…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations [Phase 3]
A Phase 3 clinical trial is evaluating the combination of Metformin with EGFR tyrosine kinase inhibitors for treating patients with Non-Smal…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study of MK-1084 in combination with other treatments for non-small cell lung cancer (MK-34…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC [Phase 3]
A Phase 3 trial is investigating whether adding glutamine and the probiotic Lactobacillus reuteri can prevent diarrhea associated with EGFR-…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluating Ivonescimab in combination with docetaxel for advanced non-small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer [Phase 1]
This Phase 1 trial is evaluating the combination of aerosolized antibiotics with pembrolizumab in patients with advanced non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer. [NA]
A clinical trial is evaluating nitroglycerin as a radiosensitizer added to radiotherapy versus conventional radiotherapy in patients with no…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial [Phase 2]
A Phase II study is exploring adding furmonertinib to local therapy for patients with inoperable, early-stage non-small cell lung cancer. Th…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Research Plan of Taiwan Precision Medicine
This document provides a clinical trial update on Taiwan's precision medicine research plan and notes that recruitment is ongoing for a stud…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements [Phase 1, Phase 2]
A phase 1/2 clinical trial is investigating optimal timing of brain radiotherapy (delayed vs upfront) in treatment‑naïve non-small cell lung…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating the combination of adagrasib with stereotactic radiosurgery for metastatic KRAS G12C-mutated non-small cel…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of Rina-S in participants with Non-small cell lung cancer and is currently re…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment [Phase 3]
A Phase 3 trial (LUNG-3) is evaluating Zongertinib vs standard treatment in patients with surgically removed non-small cell lung cancer harb…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm [Phase 2]
A Phase 2 clinical trial evaluating adjuvant pembrolizumab versus observation after curative resection in patients with stage I non-small ce…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer [NA]
This clinical trial entry describes a study evaluating lumbar punctures to detect circulating tumor DNA in the cerebrospinal fluid of patien…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer [Phase 1, Phase 2]
This is a Phase 1/Phase 2 clinical trial testing lorlatinib in combination with ramucirumab in people with non-small cell lung cancer. The s…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Alectinib Pharmacokinetic in Patients With NSCLC [Phase 1, Phase 2]
This clinical trial update describes a pharmacokinetic study of alectinib in patients with non-small cell lung cancer (ALK mutation), spanni…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients [NA]
A clinical trial update for a study evaluating pulmonary rehabilitation in patients with advanced non-small cell lung cancer, including sarc…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors [Phase 1]
This clinical trial update reports a Phase 1 dose-determining study of EXS74539 (REC-4539) in participants with select solid tumors, current…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study [Phase 2]
Phase 2 single-arm trial assessing osimertinib induction and maintenance for chemo-ineligible, unresectable stage III EGFR-positive non-smal…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion [Phase 2, Phase 3]
This is a phase 2/3 clinical trial evaluating BMS-986504 plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemother…