Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies [Phase 1]
A Phase 1 clinical trial evaluating the safety and tolerability of XmAb13676 (plamotamab) in CD20-expressing hematologic malignancies has co…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Haploidentical Stem Cell Transplant with Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL [Phase 1]
Phase 1 trial evaluating haploidentical stem cell transplantation with prophylactic natural killer donor lymphocyte infusion in lymphoma, mu…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Romidepsin in Combination With Lenalidomide in Adults With Relapsed or Refractory Lymphomas and Myeloma [Phase 1, Phase 2]
Phase 1/2 trial evaluating romidepsin with lenalidomide in adults with relapsed or refractory lymphomas and multiple myeloma has completed w…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update on a Triplex CMV vaccine designed to prevent CMV infection in patients undergoing hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Venetoclax and Selinexor in Treating Patients with Relapsed or Refractory High Risk Hematologic Malignancies [Phase 1]
This Phase 1 trial evaluated the combination of venetoclax and selinexor in relapsed or refractory high-risk hematologic malignancies, inclu…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Bendamustine + Obinutuzumab Induction With Obinutuzumab Maintenance in Untreated Mantle Cell Lymphoma [Phase 2]
Phase 2 trial of bendamustine plus obinutuzumab induction with obinutuzumab maintenance in untreated mantle cell lymphoma; the study is term…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) [Phase 2]
Phase 2 trial of a cytomegalovirus vaccine for donors and recipients undergoing allogeneic hematopoietic cell transplantation has completed,…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: High-dose Methotrexate Combined with Thiotepa and Zanubrutinib in the Treatment of Newly Diagnosed PCNSL (MTZ) [Phase 2]
A Phase 2 clinical trial is evaluating high-dose methotrexate in combination with thiotepa and zanubrutinib for newly diagnosed primary cent…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Study of a New Intravenous Drug, Called S65487, in Patients With Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study of the intravenous agent S65487 in relapsed or refractory hematologic cancers (acute myeloid leukemia, non-Hodgkin lymphoma, m…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: A Dose Finding Study of CC-96673 in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma [Phase 1]
A Phase 1 dose-finding study of CC-96673 in relapsed or refractory Non-Hodgkin's lymphoma was terminated.
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Termination of a Phase 1/2 open-label trial evaluating mosunetuzumab in combination with tiragolumab, with or without atezolizumab, in B-cel…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen [Phase 3]
This document reports the completed extension of a Phase 3 study evaluating allogeneic hematopoietic stem cell transplantation from haplotyp…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Brentuximab Vedotin in Patients With Relapsed or Refractory EBV-and CD30-positive Lymphomas [Phase 2]
Phase 2 trial evaluating brentuximab vedotin in relapsed or refractory EBV-positive, CD30-positive lymphomas; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: A Study of CC-122 to Assess the Safety and Tolerability in Japanese Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma (NHL) [Phase 1]
A Phase 1 study of CC-122 in Japanese patients with advanced solid tumors and Non-Hodgkin lymphoma was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Combination Chemotherapy With or Without Rituximab in Treating Patients With Newly Diagnosed Non-Hodgkin's Lymphoma [Phase 3]
A Phase 3 clinical trial evaluating combination chemotherapy with or without rituximab in newly diagnosed non-Hodgkin lymphoma has completed…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL [Phase 2]
Phase 2 clinical trial update evaluating point-of-care produced CAR T-cells versus commercial CAR T-cells in patients with relapsed/refracto…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phase 1 First in Human Study of ZN-d5 as a Single Agent [Phase 1]
Phase 1 first-in-human trial of ZN-d5 as a single agent has completed, with study conducted in patients with acute myeloid leukemia and non-…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: 1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating Zydelig (idelalisib) as maintenance therapy after autologous stem cell transplantation in B-cell non-Hodgkin lympho…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7443904 in Combination With Glofitamab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma [Phase 1]
A Phase 1 study evaluating RO7443904 in combination with glofitamab for relapsed/refractory B-cell non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Bendamustine Plus Rituximab Versus CHOP Plus Rituximab [Phase 3]
A Phase 3 trial comparing Bendamustine plus Rituximab vs CHOP plus Rituximab in various non-Hodgkin lymphomas has completed.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A Phase I Dose Escalation Study of the Safety and Pharmacokinetics of LAM-002A In Patients With Non-Hodgkin's Lymphoma [Phase 1]
Phase I dose-escalation study evaluating the safety and pharmacokinetics of LAM-002A in patients with Non-Hodgkin lymphoma and chronic lymph…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Romidepsin Plus Oral 5-Azacitidine in Relapsed/Refractory Lymphoid Malignancies [Phase 1, Phase 2]
A terminated Phase 1/2 trial evaluating the combination of romidepsin and oral azacitidine in relapsed/refractory lymphoid malignancies, wit…