Non-cystic Fibrosis Bronchiectasis
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis [NA]
This clinical trial evaluates the long-term use of the SIMEOX device at home for non-cystic fibrosis bronchiectasis. The study is currently …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis [Phase 2]
Phase 2 trial to assess activity and safety of SAR445399 versus placebo in adults with non-cystic fibrosis bronchiectasis; status is not yet…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease [Phase 1, Phase 2]
Genentech is conducting a Phase 1/2 study to assess the safety and effects of inhaled GDC-6988 in people with muco-obstructive diseases, inc…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBE
A translational study in Chinese patients with Non-cystic fibrosis bronchiectasis aims to phenotype and endotype the disease and is currentl…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Nebulised RESP30X Nitric Oxide Formulations in NCFB Patients With Pseudomonas Aeruginosa (Pa) [Phase 1, Phase 2]
Update on a Phase 1/2 trial of nebulised RESP30X nitric oxide formulations in non-Cystic Fibrosis Bronchiectasis patients with Pseudomonas a…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis [Phase 2]
A Phase 2 proof-of-concept trial evaluating Itepekimab, an anti-IL-33 monoclonal antibody, for efficacy, safety and tolerability in non-cyst…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Trikafta for Patients With Non-cystic Fibrosis Bronchiectasis [Phase 4]
Phase 4 trial update reporting the completion of a study evaluating Trikafta (elexacaftor/tezacaftor/ivacaftor) for non-cystic fibrosis bron…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases [NA]
A clinical trial update describing a digital physiotherapy program for children with chronic suppurative lung diseases, including protracted…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Clinical Study of RSS0343 in Healthy Subjects [Phase 1]
Phase 1 study of RSS0343 in healthy subjects is currently recruiting. The trial lists Non-cystic Fibrosis Bronchiectasis as the associated c…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Breathing Training and Exercise Capacity in Non-CFB [NA]
Mayo Clinic is recruiting participants for a clinical trial evaluating breathing training and exercise capacity in non-cystic fibrosis bronc…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Study to Evaluate the Safety, Phage Kinetics, and Efficacy of Inhaled AP-PA02 in Subjects With Non-Cystic Fibrosis Bronchiectasis and Chronic Pulmonary Pseudomonas Aeruginosa Infection [Phase 2]
This completed Phase 2 trial evaluated inhaled AP-PA02 for safety, phage kinetics, and efficacy in non-cystic fibrosis bronchiectasis with c…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis [Phase 3]
Phase 3 trial of Brensocatib in Non-Cystic Fibrosis Bronchiectasis completed; results have been posted.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB) [Phase 2]
ClinicalTrials.gov entry for a Phase 2 dose-ranging study of nebulized CSL787 in adults with Non-cystic Fibrosis Bronchiectasis. The trial a…
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CLINICAL_TRIALS approval · 2025-11-04Clinical Trial Update: An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis
Brensocatib has received marketing approval for Non-Cystic Fibrosis Bronchiectasis. The update is from an expanded-access study sponsored by…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis [Phase 2]
Verona Pharma is conducting a Phase II study of ensifentrine for non-cystic fibrosis bronchiectasis; the trial is currently recruiting.
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EMA approval · 2025-10-17First treatment for serious chronic lung disease
EMA approves Brinsupri as the first treatment for serious chronic lung disease, showing reduced and delayed pulmonary exacerbations in non-c…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Hypertonic Saline in NCFB [Phase 4]
Phase 4 clinical trial evaluating inhaled hypertonic saline for non-cystic fibrosis bronchiectasis (NCFB) is currently recruiting. Sponsored…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Phase 2a, 28-day Investigational Use Study of ARINA-1 in Non-Cystic Fibrosis Bronchiectasis (NCFBE) With Excess Mucus and Cough [Phase 2]
ARINA-1 was evaluated in a 28-day Phase 2a investigational-use trial for non-cystic fibrosis bronchiectasis with excess mucus and cough, and…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Efficacy and Safety of Benralizumab in Patients With Non-cystic Fibrosis Bronchiectasis [Phase 3]
Phase 3 trial evaluating the efficacy and safety of benralizumab for non-cystic fibrosis bronchiectasis was terminated; results have been po…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: A Multicenter, Randomized, Double-blind, Placebo-controlled Parallel-group Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of XH-S004 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis [Phase 2]
A Phase 2 multicenter randomized trial assessing the efficacy and safety of XH-S004 tablets in patients with non-cystic fibrosis bronchiecta…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Study of RSS0343 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis [Phase 2]
A Phase 2 trial evaluating RSS0343 tablets in patients with non-cystic fibrosis bronchiectasis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Impact of Support Groups for Patients With Non-Cystic Fibrosis Bronchiectasis [NA]
A completed clinical trial evaluating the impact of support groups on patients with non-cystic fibrosis bronchiectasis.
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Nutritional Status and Intake in Patients With Non-cystic Fibrosis Bronchiectasis (NCFB)
The document provides an update on a completed clinical trial studying nutritional status and intake in patients with non-cystic fibrosis br…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Simeox Therapy at Home Versus Standard of Care in NCFB Patients With CMH [NA]
A completed clinical trial comparing at-home Simeox therapy to standard care in patients with non-cystic fibrosis bronchiectasis and chronic…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Roflumilast in Non-CF Bronchiectasis Study (2019) [Phase 2]
Phase 2 study of roflumilast for non-cystic fibrosis bronchiectasis has been completed.