Non-alcoholic Steatohepatitis
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes [Phase 3]
Phase 3 trial assessing Dipeptidyl Peptidase-4 inhibitors for Type 1 diabetes and non-alcoholic steatohepatitis (NASH) has completed.
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CLINICAL_TRIALS withdrawal · 2024-03-15Clinical Trial Update: Clinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepatitis [Phase 3]
Phase 3 clinical trial evaluating metadoxine for non-alcoholic steatohepatitis was withdrawn.
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of HEC96719 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 trial assessing safety, tolerability, efficacy, and pharmacokinetics of HEC96719 in non-cirrhotic non-alcoholic steatohepatitis has …
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue [Phase 1, Phase 2]
Clinical trial update investigating a GLP-1/GIP analogue for non-alcoholic fatty liver disease in patients with type 2 diabetes; phase 1/2 w…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Efficacy and Safety of Berberine in Non-alcoholic Steatohepatitis [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of berberine in non-alcoholic steatohepatitis.
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CLINICAL_TRIALS trial_result · 2023-07-12Clinical Trial Update: the Efficacy and Safety of Diosmin on Non-diabetic Patients With Non-alcoholic Steatohepatitis. [Phase 3]
Phase 3 clinical trial updating the efficacy and safety of diosmin in non-diabetic patients with non-alcoholic steatohepatitis.
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CLINICAL_TRIALS trial_result · 2023-05-25Clinical Trial Update: Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD) [Phase 2]
A Phase 2 randomized, double-blind study evaluating vitamin E and DHA-EE for non-alcoholic fatty liver disease, completed with results poste…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: A Randomized, Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH [Phase 2]
Phase 2 randomized trial assessing safety and efficacy of EDP-305 in non-alcoholic steatohepatitis (NASH) has been terminated; results poste…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Efficacy of EYP001a in Patients With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 clinical trial of EYP001a in nonalcoholic steatohepatitis completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: Misoprostol for NASH [Phase 2]
Phase 2 clinical trial evaluating misoprostol for non-alcoholic steatohepatitis (NASH) has completed.
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects [Phase 2]
Phase 2 open-label trial evaluating MN-001 on HDL and triglycerides in subjects with NASH/NAFLD completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Comparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcoholic Steatohepatitis [Phase 3]
Phase 3 comparative trial of empagliflozin versus pioglitazone in non-diabetic patients with non-alcoholic steatohepatitis (NASH) is in an u…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Phase IIb Study to Evaluate the Efficacy and Safety of GFT505 Versus Placebo in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase IIb study evaluating GFT505 vs placebo in non-alcoholic steatohepatitis (NASH) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: An Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis [Phase 2]
Phase 2 trial evaluating nitazoxanide for safety and efficacy in reducing collagen turnover in NASH patients with fibrosis; study completed …
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH. [Phase 2]
Phase 2 clinical trial assessing safety and pharmacodynamic efficacy of 0382 in adults with NAFLD/NASH has completed with results posted in …
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus [Phase 2]
Phase 2 double-blind trial evaluating two doses of an investigational product for 16 weeks in adults with non-alcoholic steatohepatitis and …
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: Structured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver Disease [NA]
A completed clinical trial comparing a structured mobile technology–based lifestyle program to usual care for non-alcoholic fatty liver dise…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Use of a Novel Drug in People With Non-alcoholic Steatohepatitis (NASH) or Non-alcoholic Fatty Liver Disease (NAFLD) [Phase 2]
A Phase 2 trial investigating a novel drug for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) has termin…
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CLINICAL_TRIALS trial_result · 2022-01-14Clinical Trial Update: Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension [Phase 2]
Phase 2 trial of emricasan, an oral caspase inhibitor, in subjects with NASH cirrhosis and severe portal hypertension has completed with res…
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CLINICAL_TRIALS trial_result · 2021-11-12Clinical Trial Update: Study of Safety, Tolerability, and Efficacy of a Combination Treatment of LJN452 and CVC in Adult Patients With NASH and Liver Fibrosis [Phase 2]
Phase 2 study evaluating safety, tolerability, and efficacy of LJN452 combined with CVC in adult patients with non-alcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Elafibranor, PK and Safety in Children and Adolescents 8 to 17 Years of Age With Non Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 pediatric trial of Elafibranor in children 8-17 with nonalcoholic steatohepatitis was terminated; results posted but details not pro…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Tolerability, Efficacy, and PK of ZSP1601 in Patients With Non-Alcoholic Steatohepatitis (NASH) [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing tolerability, efficacy, and pharmacokinetics of ZSP1601 in non-alcoholic steatohepatitis (NASH) has compl…
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH [Phase 2]
A Phase 2 trial of elobixibat in adults with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis has completed, with results po…
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH) [Phase 2]
Phase 2 pilot study evaluating the safety of oral insulin in patients with nonalcoholic steatohepatitis (NASH) and type 2 diabetes; study co…
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 study evaluating safety, tolerability, pharmacokinetics, and efficacy of EDP-305 in non-alcoholic steatohepatitis has completed with…