Non-alcoholic Steatohepatitis
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia [Phase 2]
Phase 2 clinical trial comparing febuxostat versus vitamin E for non-alcoholic steatohepatitis with hyperuricemia; the study is active but n…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Comparative Study Between Obeticholic Acid Versus Vitamin E in Patients with Non-alcoholic Steatohepatitis [Phase 2]
An ongoing Phase 2 clinical trial comparing obeticholic acid versus vitamin E for non-alcoholic steatohepatitis is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Study of TVB-2640 in Subjects With Non-Alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 study of TVB-2640 in MASLD/MASH/NASH has completed with results posted.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: : Identification of Non-alcoholic Steato-hepatitis Cases in a Sample of Type 2 Diabetes Patients, with a Disruption of the Liver Function Tests, At the Pointe-à-Pitre University Hospital [NA]
A completed clinical trial update describes identifying non-alcoholic steatohepatitis in a sample of type 2 diabetes patients at Pointe-à-Pi…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3) [Phase 2]
Results from a Phase 2 trial evaluating the safety and efficacy of survodutide (BI456906) in adults with non-alcoholic steatohepatitis and f…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Establishment of Precise Histological Evaluation Criteria for NASH Fibrosis Reversal
This clinical trial aims to establish precise histological criteria to evaluate reversal of fibrosis in non-alcoholic steatohepatitis (NASH)…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: NASH Patient's Itinerary: Comparison of Strategies for Screening, Referring and Management of Diabetic Patients [NA]
A completed clinical trial comparing strategies for screening, referral, and management of diabetic patients with non-alcoholic fatty liver …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Soluble Fibre Supplementation in NAFLD [Phase 2]
A Phase 2 clinical trial is evaluating soluble fibre supplementation for non-alcoholic fatty liver disease and related conditions and is cur…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Evaluating the Efficacy and Safety of Roflumilast in Patients with NASH [Phase 2]
Phase 2 trial evaluates the efficacy and safety of roflumilast in patients with non-alcoholic steatohepatitis (NASH); study completed.
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Effect of Alternate Day Fasting Over Standard Medical Management Alone to Reverse Non-alcoholic Steatohepatitis. [NA]
A clinical trial in India is evaluating whether alternate-day fasting added to standard medical management can reverse non-alcoholic steatoh…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial evaluating saroglitazar magnesium for non-alcoholic steatohepatitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Combined Active Treatment in Type 2 Diabetes with NASH [Phase 4]
A Phase 4 clinical trial evaluating a combined active treatment approach for type 2 diabetes mellitus with non-alcoholic steatohepatitis (NA…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Dapagliflozin in Patients with Non-alcoholic Steatohepatitis [Phase 2]
Phase 2 trial evaluating the efficacy and safety of dapagliflozin in patients with non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Technical Validation of MR Biomarkers of Obesity-Associated NAFLD
This clinical trial update reports technical validation of magnetic resonance biomarkers for obesity-associated non-alcoholic fatty liver di…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 clinical trial evaluating synbiotics and fecal microbiota transplantation for non-alcoholic steatohepatitis is currently recruiting.
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjects With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of a recombinant human FGF21-Fc fusion protein for non-alcoholic steatohepatitis i…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Ultrasound and Attenuation Imaging
Clinical trial update reporting a completed study on ultrasound and attenuation imaging for assessing fatty liver disease, including non-alc…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Reducing Non-Alcoholic Steatohepatitis [NA]
Clinical trial update noting enrollment by invitation for a study addressing non-alcoholic steatohepatitis and related liver conditions, spo…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus [Phase 2]
A Phase 2 placebo-controlled study to evaluate the safety and efficacy of lanifibranor alone and in combination with empagliflozin in patien…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: FTIH of ECC4703 in Healthy Volunteers [EARLY_Phase 1]
The document reports the completion of first-time-in-human Phase 1 testing of ECC4703 in healthy volunteers as part of development for Non-a…
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CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: The Effect of Aerobic and Resistant Exercise Training in Patients With Non-Alcoholic Steatohepatitis [NA]
This clinical trial update describes a study evaluating aerobic and resistance exercise training in patients with non-alcoholic steatohepati…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage [Phase 2]
Phase 2 trial evaluating semaglutide in non-alcoholic steatohepatitis has completed, with results posted in May 2024.
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: MRI and Stable Isotope Tracer Studies for Detecting the Progression of Non-Alcoholic Steatohepatitis (NASH)
University of Oxford reports an MRI and stable isotope tracer study aimed at detecting progression of non-alcoholic steatohepatitis (NASH) w…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Hepatic Urea Nitrogen Handling in Patients With NASH
A clinical trial update describing a study on hepatic urea nitrogen handling in patients with non-alcoholic fatty liver disease, including n…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis [Phase 2]
Phase 2 study evaluating BFKB8488A vs placebo in non-alcoholic steatohepatitis was terminated with results posted in 2024.