Non-alcoholic Steatohepatitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial [NA]
A randomized controlled trial is recruiting to evaluate endoscopic sleeve gastroplasty for obesity in patients with MASLD/MASH and related l…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Community-based Prospective Cohort Study on Metabolic Dysfunction-Associated Fatty Liver Disease in Older Adults: From Metabolic Trajectories to Extrahepatic Outcomes
A community-based prospective cohort study is investigating metabolic dysfunction-associated fatty liver disease in older adults to understa…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Evaluation of Risk of hEpatocellular Carcinoma [NA]
This clinical trial update describes an ongoing study evaluating the risk of hepatocellular carcinoma in patients with non-alcoholic steatoh…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Human Liver ORganoids as a Model to Study the Development of Non-Alcoholic SteatOhepatitis (NASH) [NA]
A clinical trial using human liver organoids to study the development of non-alcoholic steatohepatitis, with NAFLD listed as the condition, …
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Study to Assess the Safety and Tolerability of Single Doses of AZD4076 in Healthy Male Subjects [Phase 1]
A Phase 1 study evaluating the safety and tolerability of single doses of AZD4076 in healthy male subjects has completed.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 clinical trial evaluating the combination of NNC0194 0499 and semaglutide for non-alcoholic steatohepatitis has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus [NA]
This completed clinical trial evaluated blood-test screening for liver fibrosis in people with Type 2 diabetes mellitus. The study included …
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014) [Phase 1]
Phase 1 trial evaluating Efinopegdutide in participants with hepatic impairment and non-alcoholic steatohepatitis has completed and results …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH [Phase 1, Phase 2]
Clinical trial update reports Phase 1 and Phase 2 results for ARO-HSD in healthy volunteers and patients with non-alcoholic steatohepatitis …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES) [Phase 2]
Phase 2 clinical trial NAFLD HEROES is evaluating the hepatic effects of semaglutide in non-alcoholic fatty liver disease and non-alcoholic …
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Exploratory Study of MRI Biomarkers of NASH [NA]
An exploratory MRI biomarker study in non-alcoholic fatty liver disease (NASH), with participant recruitment currently ongoing.
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: French Cohort for the Study of Non-invasive Tests of Liver Lesions in NAFLD/NASH (FreSH Cohort) [NA]
The FreSH Cohort study in France, evaluating non-invasive tests for liver lesions in non-alcoholic fatty liver disease (NAFLD/NASH), has com…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Characterization of the Intrahepatic Inflammatory Microenvironment in Patients With Non-alcoholic Steatohepatitis [NA]
Recruiting clinical trial studying the intrahepatic inflammatory microenvironment in patients with non-alcoholic steatohepatitis (NASH).
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver Disease [Phase 4]
Phase 4 clinical trial evaluating empagliflozin versus statins for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis is li…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver [NA]
A clinical trial sponsored by Université de Sherbrooke is exploring whether abnormal fat-tissue function in individuals with Type 1 diabetes…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Evaluation of a New Ultrasound System for the Non-invasive Assessment of Liver Steatosis in MASLD/MASH Patients [NA]
Ongoing clinical trial evaluating a new ultrasound system for non-invasive assessment of liver steatosis in MASLD/MASH patients.
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Effect of Adjustable Intragastric Balloon in Obese Non-alcoholic Fatty Liver Disease [NA]
A completed clinical trial assessing the effect of an adjustable intragastric balloon in obese individuals with non-alcoholic fatty liver di…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects [Phase 1]
Phase 1 open-label trial to evaluate the relative and absolute bioavailability of Cotadutide in healthy subjects, sponsored by AstraZeneca.
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EMA approval · 2025-06-20First treatment against liver scarring caused by a type of ‘fatty liver disease’
EMA approved the first treatment for liver scarring caused by a fatty liver disease. The drug is indicated for adults with moderate to advan…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) [Phase 2]
A Phase 2 study evaluating BI 685509 alone or with empagliflozin for liver cirrhosis due to viral hepatitis or non-alcoholic steatohepatitis…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Miricorilant [Phase 1]
A Phase 1 study evaluated how hepatic impairment affects the pharmacokinetics of miricorilant in Non-alcoholic Steatohepatitis (NASH). The t…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Prognostic Significance of Fatty Liver Disease in Bariatric Patients [NA]
A clinical trial from Esbjerg Hospital (University Hospital of Southern Denmark) is investigating the prognostic significance of fatty liver…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children. [Phase 1]
Phase 1 clinical trial evaluating the interaction between the investigational compound NNC0194-0499 and birth control pills; the study has c…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Clinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis [EARLY_Phase 1]
This update summarizes the results of an early-phase Phase 1 clinical trial evaluating a new approach for patients with non-alcoholic steato…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: A Study of INI-822 in Healthy Volunteers and Participants with Non-alcoholic Steatohepatitis (NASH) or Presumed NASH [Phase 1]
This clinical trial update describes INI-822 being studied in healthy volunteers and participants with non-alcoholic steatohepatitis (NASH) …