Nicotine Dependence

• CLINICAL_TRIALS trial_result · 2025-01-24
  Clinical Trial Update: Testing Financial Incentive Interventions in Dyadic-Smoker Couples [NA]

  A completed clinical trial from the University of Georgia evaluated financial incentive interventions for smoking cessation in dyadic smoker…

• CLINICAL_TRIALS withdrawal · 2025-01-23
  Clinical Trial Update: Mobile App for Smoking Cessation and Mental Health [Phase 2]

  A Phase 2 trial evaluating a mobile app for smoking cessation and mental health has been suspended, with University of Oklahoma as sponsor.

• CLINICAL_TRIALS trial_result · 2025-01-08
  Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Different Nicotine Salt Concentration Vape System Pods and Free-base Nicotine [NA]

  Completed clinical trial evaluating pharmacokinetics and pharmacodynamics of different nicotine salt pod concentrations versus free-base nic…

• CLINICAL_TRIALS trial_result · 2024-12-20
  Clinical Trial Update: Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder [Phase 2]

  Phase 2 clinical trial evaluating electronic cigarettes as a harm reduction strategy in individuals with substance use disorder has complete…

• FDA approval · 2024-12-19
  FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Oryza pharmaceuticals Inc.)

  The FDA approved a supplemental application for Bupropion Hydrochloride XL from Oryza Pharmaceuticals Inc., confirming the extended-release …

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• FDA approval · 2024-12-17
  FDA Approved: BUPROPION HYDROCHLORIDE (XL) — Supplemental Application (Vitruvias Therapeutics)

  FDA approved a supplemental application for Bupropion Hydrochloride Extended-Release (XL) from Vitruvias Therapeutics under ANDA208652, appr…

• CLINICAL_TRIALS trial_result · 2024-12-12
  Clinical Trial Update: Imaging the Neurochemistry of Drug Addiction With PET [EARLY_Phase 1]

  This early Phase 1 PET imaging study examines the neurochemical basis of drug addiction in individuals who smoke or use cannabis, with resul…

• FDA approval · 2024-12-09
  FDA Approved: VARENICLINE — Original Application (Macleods Pharmaceuticals Limited)

  FDA approved Macleods Pharmaceuticals Limited's original application for varenicline as a generic version for smoking cessation.

• CLINICAL_TRIALS research · 2024-12-09
  Clinical Trial Update: Digital Mindfulness Training Programme for Smoking Cessation and Maintenance [NA]

  A clinical trial is evaluating a digital mindfulness training program to aid smoking cessation and maintenance, sponsored by Centre Hospital…

• CLINICAL_TRIALS trial_result · 2024-12-02
  Clinical Trial Update: Varenicline for Treatment of E-cigarette Dependence [Phase 2]

  Phase 2 trial results for varenicline in treating e-cigarette dependence have been posted; the study has completed.

• FDA approval · 2024-11-26
  FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)

  FDA approved a supplemental application for bupropion hydrochloride from Sun Pharmaceutical Industries, Inc. (generic).

• CLINICAL_TRIALS trial_result · 2024-11-25
  Clinical Trial Update: A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products. [NA]

  A clinical trial evaluating changes in smokers using oral tobacco-derived nicotine products has completed and posted results.

• CLINICAL_TRIALS trial_result · 2024-11-21
  Clinical Trial Update: Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit) [Phase 2]

  Phase 2 clinical trial of Tweet2Quit, a Twitter-enabled mobile messaging program, completed with results posted evaluating its effectiveness…

• CLINICAL_TRIALS trial_result · 2024-11-15
  Clinical Trial Update: Methadone-Maintained Smokers Switching to E-Cigarettes [Phase 4]

  This Phase 4 study investigates methadone-maintained smokers who switch to electronic cigarettes and is currently active but not recruiting.

• CLINICAL_TRIALS trial_result · 2024-11-14
  Clinical Trial Update: A Study of Cytisinicline for Smoking Cessation in Adult Smokers [Phase 3]

  A Phase 3 trial evaluating cytisinicline for smoking cessation in adult smokers has completed with results posted in November 2024.

• FDA approval · 2024-11-06
  FDA Approved: NICOTINE TRANSDERMAL SYSTEM — Supplemental Application (Sam's West Inc)

  The FDA approved a supplemental application for the Nicotine Transdermal System (nicotine patch) submitted by Sam's West Inc.

• CLINICAL_TRIALS trial_result · 2024-10-31
  Clinical Trial Update: Smokers' Response to Nicotine Dependence Genotyping [NA]

  This clinical trial update notes that a study on smokers' response to nicotine dependence genotyping has completed and posted results.

• FDA approval · 2024-10-29
  FDA Approved: VARENICLINE TARTRATE — Original Application (Indoco Remedies Limited)

  FDA approved the original application for varenicline tartrate from Indoco Remedies Limited. This approval provides a generic option for smo…

• FDA approval · 2024-10-23
  FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Actavis Pharma, Inc.)

  FDA approved a supplemental ANDA for Bupropion hydrochloride extended-release (XL) from Actavis Pharma, confirming the generic product's app…

• CLINICAL_TRIALS trial_result · 2024-10-23
  Clinical Trial Update: Smoking Prevention Through Social Connections Among Adolescents - ASPIRE [NA]

  ASPIRE is a completed adolescent smoking-prevention trial evaluating whether social connections can reduce tobacco use behavior; results wer…

• FDA approval · 2024-10-17
  FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Granules Pharmaceuticals Inc.)

  FDA approved Granules Pharmaceuticals' generic bupropion hydrochloride through an original New Drug Application (ANDA), confirming its use f…

• CLINICAL_TRIALS trial_result · 2024-10-08
  Clinical Trial Update: Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction [Phase 4]

  A Phase 4 clinical trial evaluating the effectiveness of N-acetylcysteine (NAC) in motivational enhancement therapy for nicotine dependence …

• CLINICAL_TRIALS research · 2024-10-08
  Clinical Trial Update: Cognitive Behavioral Treatment with Activity Trackers for Smoking Cessation [NA]

  This clinical trial update describes a study evaluating cognitive behavioral therapy with activity trackers to support smoking cessation; re…

• FDA approval · 2024-10-07
  FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Epic Pharma, LLC)

  FDA approved Epic Pharma's supplemental application for bupropion hydrochloride extended-release (XL), confirming the approval of a generic …

• CLINICAL_TRIALS research · 2024-10-03
  Clinical Trial Update: PeRiopEratiVE SmokiNg CessaTion Trial [Phase 3]

  Phase 3 clinical trial PeRiopEratiVE SmokiNg CessaTion Trial is currently active but not recruiting, investigating smoking cessation.