Neurogenic Detrusor Overactivity
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Study to Learn How Effective and Safe the Drug 'Mirabegron' is and How Long it Stays in the Body of Children Aged 6 Months to Less Than 3 Years of Age With Neurogenic Detrusor Overactivity [Phase 3]
Phase 3 clinical trial update evaluating the safety, effectiveness, and pharmacokinetics of mirabegron in young children with neurogenic det…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization [Phase 1, Phase 2]
Phase 1/2 dose-escalation study of EG110A delivered via intradetrusor injections for neurogenic detrusor overactivity related to spinal cord…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Optimization of OnabotulinumtoxinA (BTX-A) Injection for the Treatment of Neurogenic Lower Urinary Tract Dysfunction [NA]
A completed clinical trial evaluating optimized injections of OnabotulinumtoxinA for neurogenic lower urinary tract dysfunction has posted r…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Improving Pelvic Rehabilitation Using Epidural Stimulation After Spinal Cord Injury [NA]
This clinical trial update describes a University College London study testing epidural stimulation to improve pelvic rehabilitation after s…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron Oral Suspension in Pediatric Subjects From 3 to Less Than 12 Years of Age With Neurogenic Detrusor Overactivity (NDO) or Overactive Bladder (OAB) [Phase 1]
This completed Phase 1 pediatric study assessed the pharmacokinetics, safety, and tolerability of Mirabegron oral suspension in children age…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Single Dose Study to Measure Blood Levels and Safety of a Drug for Children With Overactive Bladder [Phase 1]
Phase 1 single-dose pediatric trial to measure blood levels and safety of a drug for overactive bladder and neurogenic detrusor overactivity…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron OCAS (Oral Controlled Absorption System) in Pediatric Subjects With Neurogenic Detrusor Overactivity or Overactive Bladder [Phase 1]
Phase 1 study assessing pharmacokinetics, safety and tolerability of Mirabegron OCAS in pediatric patients with Neurogenic Detrusor Overacti…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC [Phase 2, Phase 3]
A pediatric study of vibegron for neurogenic detrusor overactivity in children aged 2 to less than 18 years is currently recruiting, coverin…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Dorsal Genital Nerve Stimulation for Bladder Management After SCI [NA]
Clinical trial update on Dorsal Genital Nerve Stimulation for bladder management after spinal cord injury; the study is currently active but…
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity [Phase 2]
Phase 2 open-label pharmacodynamic/pharmacokinetic study of multiple doses of darifenacin liquid suspension in children with neurogenic detr…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1 [Phase 3]
Phase 3 clinical trial investigating Dysport for urinary incontinence due to neurogenic detrusor overactivity related to spinal cord injury …
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 2 [Phase 3]
A Phase 3 study evaluating Dysport (abobotulinumtoxinA) for urinary incontinence due to neurogenic detrusor overactivity in adults with spin…
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Effects of Rec 0/0438 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Injury [Phase 1, Phase 2]
Phase 1/2 trial updates for Rec 0/0438 in neurogenic detrusor overactivity due to spinal cord injury completed.
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CLINICAL_TRIALS trial_result · 2020-10-26Clinical Trial Update: Open-label Long-term Extension Study of Fesoterodine in Japanese Subjects With Neurogenic Detrusor Overactivity. [Phase 3]
Open-label long-term extension study of fesoterodine in Japanese subjects with neurogenic detrusor overactivity completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: Open-label Phase 3 Study With Mirabegron in Children From 3 to Less Than 18 Years of Age With Neurogenic Detrusor Overactivity [Phase 3]
Open-label Phase 3 trial of mirabegron in children aged 3 to less than 18 with neurogenic detrusor overactivity completed; results were post…
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: A Long-Term Extension Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity [Phase 3]
A long-term extension study of onabotulinumtoxinA (BOTOX) for urinary incontinence due to neurogenic detrusor overactivity has completed Pha…
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CLINICAL_TRIALS trial_result · 2019-12-26Clinical Trial Update: Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI [Phase 4]
Phase 4 clinical trial update investigating Botox for neurogenic detrusor overactivity and prevention of autonomic dysreflexia after spinal …
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CLINICAL_TRIALS trial_result · 2019-10-30Clinical Trial Update: Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity in Pediatric Patients [Phase 3]
Phase 3 clinical trial evaluating onabotulinumtoxinA (BOTOX) for urinary incontinence due to neurogenic detrusor overactivity in pediatric p…
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CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity [Phase 3]
Phase 3 trial completed evaluating the long-term safety, tolerability, and metabolism of a solifenacin liquid suspension in children aged 5 …
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: A Clinical Study to Investigate How Solifenacin Fluid is Taken up, How Long it Stays in the Body and How Effective and Safe it is in Treating Children Aged From 6 Months to Less Than 5 Years With Symptoms of Neurogenic Detrusor Overactivity (NDO) [Phase 3]
Phase 3 pediatric trial evaluating pharmacokinetics, safety, and efficacy of solifenacin for neurogenic detrusor overactivity in children ag…
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CLINICAL_TRIALS trial_result · 2018-03-26Clinical Trial Update: A Safety and Efficacy Study of BOTOX® (Botulinum Toxin Type A) in Patients With Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in India
This clinical trial update reports on a safety and efficacy study of BOTOX (botulinum toxin type A) for urinary incontinence due to neurogen…
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CLINICAL_TRIALS trial_result · 2017-12-15Clinical Trial Update: Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence From Neurogenic Detrusor Overactivity in Belgium
A completed clinical trial evaluating Botulinum Toxin Type A (BOTOX) for urinary incontinence due to neurogenic detrusor overactivity in Bel…
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Effect of Botulinum Toxin A on Neurogenic Detrusor Overactivity in Chronic Spinal Cord Injured Patients
This clinical trial update reports on the completed study evaluating the effect of Botulinum Toxin A on neurogenic detrusor overactivity in …
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CLINICAL_TRIALS trial_result · 2016-09-22Clinical Trial Update: Evaluation of Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korea
A completed Korea-based clinical trial evaluated the safety and efficacy of botulinum toxin type A (BOTOX) for urinary incontinence due to n…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Heart Rate Variability (HRV) in Patients With Neurogenic Detrusor Overactivity (NDO) Before and After Botulinum Neurotoxin Type A (BoNT/A) Intradetrusor Injections
This completed clinical trial evaluated heart rate variability in patients with neurogenic detrusor overactivity before and after intradetru…