Neurofibromatosis Type
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1 [Phase 2]
This entry notes the completion of a randomized, placebo-controlled Phase 2 trial of lovastatin in children with Neurofibromatosis Type 1, w…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 [Phase 2]
Phase 2 trial evaluating topical diclofenac after laser microporation for cutaneous neurofibromas in Neurofibromatosis type 1 has completed.
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma [Phase 2]
A Phase 2 trial of Antineoplaston Therapy for neurofibroma and schwannoma sponsored by Burzynski Research Institute has been terminated.
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CLINICAL_TRIALS research · 2017-07-25Clinical Trial Update: Neurofibromatosis Type 1 Patient Registry
This entry reports a completed clinical trial registry for Neurofibromatosis Type 1, sponsored by Washington University School of Medicine (…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform Neurofibromas [Phase 1, Phase 2]
A Phase 1/2 pilot study evaluated imatinib mesylate (Gleevec) in patients with neurofibromatosis type 1 and plexiform neurofibromas; the tri…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T [Phase 2]
Phase 2 trial investigating everolimus for disfiguring cutaneous lesions in Neurofibromatosis Type 1 has completed with results posted in 20…
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CLINICAL_TRIALS research · 2017-05-09Clinical Trial Update: Neurofibromatosis Type 1 Brain Tumor Genetic Risk
Completed clinical trial investigating genetic risk factors for brain tumors in children with Neurofibromatosis Type 1.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas [EARLY_Phase 1]
This update reports an early-phase 1 trial of nilotinib (Tasigna) in patients with Neurofibromatosis type 1 and plexiform neurofibromas, wit…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Neurobiology and Treatment of Reading Disability in NF-1 [NA]
This completed study investigates the neurobiological basis and treatment approaches for reading disability in Neurofibromatosis Type 1. The…
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas [Phase 2]
A Phase II clinical trial evaluating the mTOR inhibitor sirolimus (Rapamune) for neurofibromatosis type 1–related plexiform neurofibromas ha…
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CLINICAL_TRIALS trial_result · 2017-01-10Clinical Trial Update: Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1 [Phase 1]
This Phase 1 study evaluates topical Imiquimod 5% cream for treating cutaneous neurofibromas in adults with Neurofibromatosis Type 1; the tr…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) [Phase 1]
This document reports the completion of a Phase 1 clinical trial assessing the safety of lovastatin in individuals with Neurofibromatosis ty…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1 [EARLY_Phase 1]
An early-phase Phase 1 trial evaluating ranibizumab for neurofibromas in Neurofibromatosis Type 1 has completed.
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Neuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1 [NA]
This clinical trial update reports on neuropsychological impairment and quality of life in Neurofibromatosis Type 1.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype [NA]
Completed clinical trial evaluating resiliency training delivered via Skype videoconferencing for patients with Neurofibromatosis types 1, 2…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1) [Phase 2]
Phase 2 trial evaluating RAD001 (everolimus) for plexiform neurofibromas in Neurofibromatosis Type 1 was terminated, with results posted in …
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas [Phase 2]
Phase 2 trial of sunitinib (Sutent) in neurofibromatosis type 1 with plexiform neurofibromas was terminated; results were posted on 2016-05-…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas [Phase 2]
Phase II study assessing imatinib (Gleevec) in neurofibromatosis type 1 patients with plexiform neurofibromas has completed, with results po…
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas [Phase 2]
Phase 2 trial of sorafenib in children and young adults with recurrent or progressive low-grade astrocytomas, including patients with neurof…
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CLINICAL_TRIALS research · 2016-02-11Clinical Trial Update: Analysis of Plasma for Diagnosis and Follow-up of Neurofibromatosis Type 1
This clinical trial update discusses evaluating plasma-based analysis for diagnosing and monitoring neurofibromatosis type 1.
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Reliability of Functional Outcome Measures in Neurofibromatosis 1
This entry reports on a completed clinical trial evaluating the reliability of functional outcome measures in Neurofibromatosis type 1.
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Functional Imaging and Reading Deficit in Children With NF1 [NA]
A completed clinical trial assessing functional imaging and reading deficits in children with Neurofibromatosis Type 1.
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CLINICAL_TRIALS trial_result · 2015-07-22Clinical Trial Update: Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 Patients
A clinical trial update reports subtle myocardial deformation abnormalities in asymptomatic patients with Neurofibromatosis Type 1.
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: The Cognitive Variability in NF1 and TSC Monozygotic Twins
Clinical trial update examining cognitive variability in monozygotic twins with Neurofibromatosis Type I and Tuberous Sclerosis Complex.
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas [Phase 1]
Phase 1 clinical trial evaluating pirfenidone in young patients with Neurofibromatosis Type 1 and plexiform neurofibromas has completed.