Neurofibromatosis Type
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN [Phase 1, Phase 2]
Phase 1/2 trial evaluating pharmacokinetics, safety, and efficacy of a granule formulation of selumetinib in children with Neurofibromatosis…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II [Phase 2]
Phase II clinical trial evaluating photodynamic therapy for benign dermal neurofibromas in Neurofibromatosis Type 1. The study is currently …
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1
The clinical trial evaluating mitochondrial dysfunction in Neurofibromatosis type 1 has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas [Phase 2]
Phase II trial of binimetinib in children and adults with NF1-associated plexiform neurofibromas has completed. Results have been posted.
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CLINICAL_TRIALS other · 2025-04-04Clinical Trial Update: US Selumetinib Registry
The US Selumetinib registry trial for Neurofibromatosis Type 1 with plexiform neurofibromas has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial [NA]
The document reports the completion and posting of results from a clinical trial evaluating the iCanCope mobile app for chronic pain in adul…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Phase II Trial of Poly-ICLC for Low-Grade Gliomas [Phase 2]
A terminated Phase II trial evaluating poly-ICLC for low-grade gliomas in NF1 patients has posted results.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas [Phase 3]
A Phase 3 clinical trial update on FCN-159 for symptomatic, inoperable Neurofibromatosis type 1-related plexiform neurofibromas, sponsored b…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1 [NA]
This clinical trial update reports completion of a study evaluating clinical hypnosis and home blood pressure monitoring for managing hypert…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas [Phase 1]
Phase 1 trial evaluating dosing and tolerability of deoxycholic acid versus polidocanol for treating cutaneous neurofibromas in neurofibroma…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas [Phase 1]
A Phase 1 trial evaluating tolerability of device-based therapies for cutaneous neurofibromas in Neurofibromatosis type 1 has completed.
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Gene Therapy for Neurofibromatosis Type 2 (NF2) with ST002 [NA]
A gene therapy trial for neurofibromatosis type 2 using ST002 is currently NOT_YET_RECRUITING, sponsored by the Cancer Institute and Hospita…
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CLINICAL_TRIALS other · 2025-01-08Clinical Trial Update: Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children [Phase 2]
The document discusses a Phase 2 trial of low-dose selumetinib for plexiform neurofibromas in Chinese children. The study status is not yet …
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: MicroRNAs in Patients With Neurofibromatosis Type 1
Completed clinical trial evaluating microRNAs in patients with Neurofibromatosis Type 1, including glioma cases.
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1 [Phase 1, Phase 2]
This Phase 1/2 clinical trial evaluates FCN-159 in adults and children with Neurofibromatosis type 1 and plexiform neurofibroma to assess sa…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: HIFU Treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1: Safety and Efficacy [NA]
This completed clinical trial evaluated high-intensity focused ultrasound (HIFU) for treating cutaneous neurofibromas in Neurofibromatosis T…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Molecular Aspects of Preimplantation Genetic Diagnosis for NF1
Clinical trial update on the molecular aspects of preimplantation genetic diagnosis for Neurofibromatosis Type 1 (NF1). The study status is …
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 [Phase 2]
A Phase 2 clinical trial evaluating the antioxidant N-acetylcysteine for children with Neurofibromatosis type 1; current status is ACTIVE_NO…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule [Phase 2]
This Clinical Trial Update indicates a Phase 2 study evaluating smeitinib hydrosulfate capsules for Neurofibromatosis type 1, with recruitme…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule [Phase 2]
A Phase 2 clinical trial evaluating Smetinib Hydrosulfate Capsule for Neurofibromatosis type 1 is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery [Phase 1]
This Phase 1 clinical trial evaluated a vaccine therapy for malignant peripheral nerve sheath tumors that are metastatic, recurrent, or unre…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)
The NCI-sponsored clinical trial NCT04774289, now completed, compared the incidence of malignant peripheral nerve sheath tumors in people wi…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments
A completed clinical trial analysis evaluating neurobehavioral data collected from participants with HIV, brain tumors, and Neurofibromatosi…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)
This completed clinical trial investigated relationship stressors in parents of children with cancer or Neurofibromatosis Type 1 (NF1), spon…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia [Phase 2]
A Phase 2 clinical trial update on trametinib for relapsed or refractory Juvenile Myelomonocytic Leukemia (JMML), including patients with Ne…