Neurofibroma

• EMA approval · 2026-08-13
  EMA Authorised: Ezmekly (mirdametinib) — Merck Europe B.V.

  EU authority authorised Ezmekly (mirdametinib) for Neurofibromatosis type 1 with neurofibromas, including plexiform neurofibroma, under cond…

• CLINICAL_TRIALS trial_result · 2026-04-14
  Clinical Trial Update: Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

  This is an update on a completed observational clinical trial studying the natural history and biology of skin neurofibromas in Neurofibroma…

• CLINICAL_TRIALS research · 2026-04-09
  Clinical Trial Update: Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

  This clinical trial update describes the development of patient-reported outcome measures to assess tumor visibility and appearance concerns…

• CLINICAL_TRIALS research · 2026-03-20
  Clinical Trial Update: Natural History Study of Patients With Neurofibromatosis Type I

  The National Cancer Institute is conducting an observational natural history study of patients with Neurofibromatosis Type 1. The study is c…

• CLINICAL_TRIALS trial_result · 2025-12-26
  Clinical Trial Update: Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent [Phase 2]

  Phase 2 ascending-dose study of RVP-001, a manganese-based MRI contrast agent, completed to assess safety and preliminary efficacy in CNS le…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS research · 2025-06-10
  Clinical Trial Update: Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

  An observational non-interventional study in Russia evaluating outcomes for patients with plexiform neurofibromatosis type 1 starting selume…

• CLINICAL_TRIALS trial_result · 2020-06-18
  Clinical Trial Update: Stereotactic Body Radiotherapy for Spine Tumors [NA]

  Clinical trial update on stereotactic body radiotherapy for spine tumors with completed status and results posted.

• CLINICAL_TRIALS withdrawal · 2017-02-10
  Clinical Trial Update: Proton Radiation Therapy for Spinal Tumors [NA]

  A University of Florida-sponsored trial evaluating proton radiation therapy for spinal nerve sheath tumors has been withdrawn.