Neurodegenerative Diseases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Results: A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation [Phase 2]
Phase 2 trial results for XPro1595 in early Alzheimer's disease with inflammatory biomarkers have been completed and results posted.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
The Neurodevelopmental and Behavioral Phenotyping Screening Protocol is an NIMH-sponsored clinical trial protocol currently recruiting, inve…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline - DECISION
This clinical trial update describes ongoing research on decision-making, ethical consent, and interactive dialogue in neurocognitive declin…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease [Phase 1]
Phase 1 clinical trial update indicates recruitment for a kisspeptin-based approach to quantify GnRH neuronal function across health and dis…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Novel Technologies to Measure Vision-related Quality of Life
A clinical trial update announcing a study evaluating novel technologies to measure vision-related quality of life in neurodegenerative dise…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
This clinical trial update describes the HSPseq Genomic Sequencing Initiative at Boston Children's Hospital to study genomic sequencing in h…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: NAD+ Oral Supplement Pilot Intervention in Adult Females [NA]
A completed pilot trial evaluated an NAD+ oral supplement in adult females for cognitive change and inflammation, with potential relevance t…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research
This document describes the Brain Health Registry, an online platform from UCSF to identify and assess potential brain research subjects. En…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)
Beijing Tiantan Hospital is conducting an ongoing enrollment study to establish normal Chinese lifespan brain charts, enrolling by invitatio…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Clinical Research on Stem Cell Therapy for Parkinson's Disease [Phase 1]
Phase 1 clinical trial update for a stem cell therapy intended for Parkinson disease; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: The Effects of the MIND Diet on Oxidative Stress, Inflammation and Neurodegenerative Risk Biomarkers [NA]
A completed clinical trial evaluated whether the MIND diet influences oxidative stress, inflammation, and neurodegenerative risk biomarkers.
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Novel Diagnostic and Disease Stage Biomarkers in AD
The update indicates the completed trial from the Danish Dementia Research Centre evaluating novel diagnostic and disease-stage biomarkers f…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Prospective cohort study at Xiangya Hospital recruiting to investigate sleep-disordered breathing and its relationships with multimorbidity,…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Home Exercise for Individuals with Neurodegenerative Disease [NA]
A clinical trial update for a home-based exercise program targeting individuals with neurodegenerative diseases, including leukodystrophy, a…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Observational Pharmaco-Epidemiology Research & Analysis
An observational pharmaco-epidemiology research study sponsored by Epividian is currently recruiting across multiple disease areas, includin…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Translocator Protein PET/CT in Various TSPO-Related Disease
This clinical trial is studying TSPO-targeted PET/CT imaging across neuroinflammation, stroke, and neurodegenerative diseases and is current…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Simulation-informed Modelling and Personalized Evaluation (SIMPLE) in Ageing Populations
This update describes the SIMPLE trial, a study applying simulation-informed modelling and personalized evaluation to aging populations, foc…
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: A Low-Cost Balance Training Platform Using Augmented Reality in Neurorehabilitation: a Usability Study [NA]
Usability study of a low-cost balance training platform using augmented reality in neurorehabilitation, currently recruiting participants.
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population [NA]
This clinical trial update describes ongoing recruitment for a study evaluating adherence to long-term exoskeleton rehabilitation to treat l…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Cord Blood Serum in the Treatment of Neuro-Degenerative Ophthalmic Diseases. 1-Glaucoma [NA]
Clinical trial evaluating cord blood serum for glaucoma and other neurodegenerative ophthalmic diseases has completed.
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: [18F]MC225-PET in Neurodegenerative Disease [Phase 1, Phase 2]
Early-phase trial update for [18F]MC225-PET imaging in neurodegenerative diseases, including Alzheimer’s disease and related conditions (Pha…
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CLINICAL_TRIALS trial_result · 2022-11-25Clinical Trial Update: Smell, Voice and Nasal Swabs as Markers for Neuro-degenerative Disorders [NA]
Clinical trial update on using smell, voice, and nasal swabs as markers for neuro-degenerative disorders; status completed with results post…
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EMA approval · 2022-05-24EMA Authorised: Amifampridine SERB (amifampridine phosphate) — SERB SA
European Medicines Agency authorises amifampridine phosphate (SERB) for various neuromuscular and autoimmune conditions, with Lambert-Eaton …
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CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: [18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease [Phase 2]
Phase 2 clinical trial update for [18F]THK-5351 PET imaging across Alzheimer's disease, mild cognitive impairment, and other neurodegenerati…
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FDA approval · 2015-07-17FDA Approved: FLUDEOXYGLUCOSE F18 — Original Application (The Regents of the University of Michigan)
The FDA approved the Original Application for Fludeoxyglucose F-18, a radiopharmaceutical used for PET imaging. The submission was sponsored…