Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours [NA]
The SIOPEN BIOPORTAL is an international registry connected to a virtual biobank for patients with peripheral neuroblastic tumors, with recr…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma [Phase 1]
Phase 1 clinical trial updating study design to combine dinutuximab beta with two chemotherapy regimens for neuroblastoma; recruiting.
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Study of Chemoimmunotherapy for High-Risk Neuroblastoma [EARLY_Phase 1]
An early-phase Phase 1 trial evaluating chemoimmunotherapy for high-risk neuroblastoma conducted by Memorial Sloan Kettering Cancer Center i…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) [Phase 3]
Phase 3 clinical trial update for high-risk neuroblastoma under the SIOP-Europa-Neuroblastoma (SIOPEN) consortium; the study is currently re…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma [Phase 2]
A Phase 2 clinical trial update for Naxitamab (hu3F8) in pediatric high-risk or refractory/recurrent neuroblastoma (NCT06013618) is currentl…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Bivalent Vaccine With Escalating Doses of the Immunological Adjuvant OPT-821, in Combination With Oral β-glucan for High-Risk Neuroblastoma [Phase 1, Phase 2]
Clinical trial update on a bivalent vaccine using the OPT-821 adjuvant with oral beta-glucan for high-risk neuroblastoma. The Phase 1/2 stud…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01 [Phase 1]
Phase 1 clinical trial evaluating ENCIT-01, an engineered neuroblastoma cellular immunotherapy, in patients with neuroblastoma or ganglioneu…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Risk Model for Metastasis Detection of Neuroblastoma
Clinical trial update describing a study to develop a risk model for detecting metastasis in neuroblastoma, currently enrolling by invitatio…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial is evaluating NK cell infusions in combination with irinotecan, temozolomide, and dinutuximab for relaps…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Clinical Trial on Autologous NK Cells Combined With GD2 Monoclonal Antibody in the Treatment of Children With Newly Diagnosed High-risk or Relapsed/Refractory Neuroblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating autologous natural killer (NK) cells in combination with a GD2-targeted monoclonal antibody for newly …
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating autologous B7-H3 CAR T cells in relapsed/refractory solid tumors, including neuroblastoma, sarcoma, and osteosarcom…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Arsenic Trioxide With MAPK Inhibitors and Chemotherapy for Stage 4/M Neuroblastoma [Phase 2]
Phase 2 clinical trial evaluating arsenic trioxide in combination with MAPK inhibitors and chemotherapy for stage 4/metastatic neuroblastoma…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Safety and Efficacy of Systemic Allogenic NK Cells in R/R Neuroblastoma [Phase 1]
Phase 1 trial assessing safety and efficacy of systemic allogeneic NK cells in relapsed/refractory neuroblastoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) [NA]
This entry reports on the MICCHADO trial, which investigates the biological characterization of high-risk childhood cancers. The sponsor is …
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Safety and Efficacy of CAR-T Cell Therapy for Relapsed/refractory Neuroblastoma and Desmoplastic Small Round Cell Tumors: a Single-arm, Open-label Trial. [Phase 1, Phase 2]
This document outlines an ongoing single-arm, open-label Phase 1/2 trial assessing the safety and efficacy of CAR-T cell therapy in relapsed…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors [Phase 1]
Ascentage Pharma is conducting a Phase 1 trial of APG-115 alone or in combination with APG-2575 in children with recurrent or refractory neu…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma. [Phase 1]
Phase I trial evaluating umbilical cord blood-derived natural killer (NK) cell therapy in children with high-risk, relapsed/refractory neuro…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: MCT for the Harvard/UCSF ROBIN Center [NA]
A clinical trial update showing recruitment is ongoing for an MCT study at the Harvard/UCSF ROBIN Center. The study targets glioma, pediatri…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
A clinical trial from Xinhua Hospital and Shanghai Jiao Tong University aims to improve diagnosis and grading of pediatric solid tumors usin…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: The Adoptive Immunotherapy for Solid Tumors Using Modified Autologous CIK Cells [Phase 1, Phase 2]
An ongoing Phase 1/Phase 2 clinical trial at Siriraj Hospital is evaluating modified autologous cytokine-induced killer (CIK) cell immunothe…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Chimeric Natural Killer Receptor-Universal T Cells for Relapsed or Refractory Neuroblastoma [Phase 1]
Phase 1 clinical trial evaluating chimeric natural killer receptor-universal T cells for relapsed or refractory neuroblastoma. The study is …
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Anti-GD2 CAR T cells in pediatric patients with high-risk or relapsed/refractory neuroblastoma and other…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Pencil Beam Scanning Proton Beam Radiotherapy for the Management of Abdominal Neuroblastoma [NA]
The trial investigates pencil beam scanning proton beam radiotherapy for neuroblastoma and is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors [Phase 2]
Phase 2 pediatric trial evaluating palbociclib in combination with chemotherapy for recurrent or refractory solid tumors, including Ewing sa…