Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors [Phase 1]
GAIA-102 is being evaluated in a Phase 1 trial for refractory/relapsed neuroblastoma and other pediatric solid tumors, and the study is curr…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-DOTA0-Tyr3-Octreotate in Children With Refractory or Recurrent Neuroblastoma Expressing Somatostatin Receptors. [Phase 1]
Phase 1 clinical study evaluating the safety of Lutetium-177 DOTATATE peptide receptor radionuclide therapy in children with neuroblastoma e…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
This clinical trial update describes biomarker analysis in tumor tissue from patients with newly diagnosed neuroblastoma or ganglioneuroblas…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Genomic Structural Variation in Cancer Susceptibility
This clinical trial update discusses ongoing research on genomic structural variation in cancer susceptibility and lists several cancer cond…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma [Phase 2]
This clinical trial update describes a Phase 2 study evaluating myeloablative consolidation therapy with tandem autologous stem cell rescue …
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome
Clinical trial evaluating molecular characteristics of neuroblastic tumors and how these features correlate with clinical outcomes in neurob…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating infusion of NY-ESO-1–specific TCR-engineered lymphocytes in patients with NY-ESO-1-expressing…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/Paraganglioma
A clinical trial evaluating imaging agents targeting somatostatin receptors and norepinephrine transporters for diagnosis and staging of neu…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors [Phase 1]
Phase 1 study evaluating flavored oral irinotecan VAL-413 (Orotecan) with temozolomide for recurrent pediatric solid tumors is currently rec…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma [Phase 1]
Phase 1 clinical trial evaluating autologous NKT cells engineered with a GD2-targeted CAR and interleukin-15 for neuroblastoma in children; …
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Quadruple Immunotherapy for Neuroblastoma [Phase 2]
Phase 2 clinical trial evaluating quadruple immunotherapy for recurrent Neuroblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors
Clinical trial update evaluating preoperative arteriography to identify the Adamkiewicz artery before surgery for basi-thoracic neuroblastic…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Comparison of 18F Labeled Analog of MIBG (18F-MFBG) PET/CT and 123I-MIBG SPECT in Pediatric Patients With Neuroblastoma. [Phase 2]
This update describes a Phase 2 clinical trial comparing 18F-MFBG PET/CT to 123I-MIBG SPECT imaging in pediatric patients with neuroblastoma…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive Method
This clinical trial investigates fertility preservation in children with solid tumors and evaluates detection of residual disease using a hi…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating cabozantinib as maintenance therapy to prevent progression or recurrence in high-risk pediatric solid tumors is cur…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: 18F-mFBG PET Imaging in the Evaluation of Neuroblastoma
This clinical trial update outlines a study evaluating 18F-mFBG PET imaging for the assessment of neuroblastoma, currently in recruitment.
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A Study of N9 Chemotherapy in Children With Neuroblastoma [EARLY_Phase 1]
An early-phase Phase 1 study evaluating N9 chemotherapy in children with neuroblastoma. The trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: GSL Synthetase Inhibitor Plus GM-CSF and/ or Immune Checkpoint Inhibitor in Previously Treated High-Risk Neuroblastoma. [EARLY_Phase 1]
An early-phase clinical trial evaluating a GSL Synthetase Inhibitor in combination with GM-CSF and/or an immune checkpoint inhibitor for pre…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial evaluating the safety and efficacy of IR-101 for relapsed/refractory neuroblastoma is currently recr…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Parental Decision-Making for Children With Relapsed Neuroblastoma
Clinical trial update from Dana-Farber Cancer Institute examining parental decision-making for children with relapsed neuroblastoma; the stu…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) [Phase 1]
ClinicalTrials.gov entry updates the Phase 1 study of C7R-GD2.CART cells for relapsed or refractory GD2-positive cancers, including neurobla…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Expanded Access Protocol for the Use of SL-28 in the Treatment of Advanced Solid Tumors
This clinical trials update describes an expanded access protocol for SL-28 in patients with advanced solid tumors and lists eligible condit…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: 131I-Labeled MIBG for Refractory Neuroblastoma: A Compassionate Use Protocol
This document reports a compassionate-use protocol for 131I-labeled metaiodobenzylguanidine (MIBG) to treat refractory neuroblastoma.