Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: SPEARHEAD-3 Pediatric Study [Phase 1, Phase 2]
SPEARHEAD-3 is a pediatric study enrolling in Phase 1 and Phase 2 across multiple cancers, including synovial sarcoma, malignant peripheral …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma [Phase 1]
Phase 1 trial evaluating NKG2D.Zeta-NK cell conditioning combined with C7R.GD2.CAR-T cells in patients with relapsed or refractory neuroblas…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study. [Phase 1, Phase 2]
Multi-center, single-arm Phase I/II clinical trial assessing safety and preliminary efficacy of apatinib mesylate in combination with an iri…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma [Phase 2]
Phase 2 clinical trial evaluating the combination of Eflornithine (DFMO) and Etoposide for relapsed/refractory Neuroblastoma; currently recr…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma [Phase 2]
A Phase 2 trial update indicates naxitamab is being added to induction therapy for newly diagnosed high-risk neuroblastoma, with patient rec…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and Ganglioneuroblastoma [Phase 3]
A Phase 3 clinical trial in pediatric patients with refractory or relapsed high-risk neuroblastoma and ganglioneuroblastoma is evaluating ch…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) [Phase 1]
Phase 1 SABRE trial evaluating selective antigen-specific T cells and CAR T cells in relapsed/refractory embryonal tumors, including rhabdom…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Biomarkers of Resiliency In Childhood Cancer Surgery
Clinical trial update from Mayo Clinic on biomarkers of resiliency in pediatric cancer surgery, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Neuroblastoma Maintenance Therapy Trial [Phase 2]
This document announces a Phase 2 neuroblastoma maintenance therapy trial that is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Multi-Arm, Platform Trial For Relapsed Neuroblastoma [Phase 1, Phase 2]
A multi-arm platform trial for relapsed neuroblastoma spanning Phase 1 and Phase 2 is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
Clinical trial update describing a long-term follow-up study of late effects after treatment in patients with high-risk neuroblastoma; the s…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Combination Therapy of Antibody Hu3F8 With Granulocyte- Macrophage Colony Stimulating Factor (GM-CSF) in Patients With Relapsed/Refractory High-Risk Neuroblastoma [Phase 1, Phase 2]
Clinical trial update describing a phase 1/phase 2 study of Hu3F8 in combination with GM-CSF for relapsed/refractory high-risk neuroblastoma…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Phase II Study of Chidamide-Dinutuximab Beta-Irinotecan-Temozolomide for Refractory/Relapsed Neuroblastoma in Children [Phase 2]
A Phase II clinical trial is evaluating chidamide, dinutuximab beta, irinotecan, and temozolomide for refractory/relapsed neuroblastoma in c…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Phase II Study of Proton Radiation Therapy for Neuroblastoma [NA]
A Phase II clinical trial is evaluating proton radiation therapy for neuroblastoma and related ganglioneuroblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma [Phase 1]
Phase 1 clinical trial update on GPC2 CAR T cells for relapsed/refractory neuroblastoma and metastatic retinoblastoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma [Phase 1]
A Phase 1 clinical trial evaluating PHOX2B PC-CAR T cells for relapsed or refractory neuroblastoma, with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating hALK.CAR T cells in children with relapsed or refractory high-risk neuroblastoma; the study is current…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating allogeneic expanded gamma delta T cells combined with GD2-targeted chemoimmunotherapy in relapsed/refracto…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma [Phase 3]
A Phase 3 clinical trial update investigates response and biology-based risk-factor guided therapy for younger patients with non-high risk n…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Clinical Study of Eflornithine After Immunotherapy for High-risk Neuroblastoma（CSHEIN）
Clinical trial update indicating the status of a study evaluating eflornithine after immunotherapy for high-risk neuroblastoma; the trial is…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study [NA]
A pilot PET imaging trial using the 124I-labeled humanized antibody 3F8 to visualize solid tumors, including melanoma, neuroblastoma, and sa…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: 18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma [EARLY_Phase 1]
This report updates an early-phase 1 trial using 18F-fluorodopamine PET imaging in neuroblastoma and pheochromocytoma. The study is currentl…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers [Phase 2, Phase 3]
The DETERMINE trial treatment arm 01 is evaluating Alectinib in adult, paediatric and teenage/young adult patients with ALK-positive cancers…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations [Phase 2, Phase 3]
An ongoing DETERMINE trial (arm 06) investigates capmatinib for MET-dysregulated cancers, with Phase 2/3 testing and current recruitment.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…