Neural Tube Defects
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Fetoscopic Repair of Isolated Fetal Spina Bifida [NA]
Clinical trial update on fetoscopic repair for isolated fetal spina bifida; the study is active but not currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Understanding Effects of Folic Acid on the Methylosome and Transcriptome of Women With Spina Bifida Affected Pregnancies [NA]
A completed clinical trial evaluating the effects of folic acid on the methylosome and transcriptome in pregnancies affected by spina bifida…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Folic Acid Salt Study (FISFA Zambia) [NA]
Clinical trial update for the Folic Acid Salt Study (FISFA Zambia) sponsored by the University of Alabama at Birmingham; the study is not ye…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Patch vs. No Patch Fetoscopic Meningomyelocele Repair Study [Phase 1]
This Phase 1 clinical trial, sponsored by Baylor College of Medicine, compares patch-assisted fetoscopic meningomyelocele repair with patchl…
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FDA approval · 2026-01-26FDA Approved: QUIOFIC — Original Application (Solubiomix, LLC)
FDA approved QUIOFIC (folic acid) through an Original New Drug Application by Solubiomix, LLC.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases [NA]
A clinical trial update on the safety and efficacy of devices used in fetoscopic neural tube defect repair. The study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels
Completed clinical trial evaluating iodized salt to improve serum levels of folate, vitamin B12, and iron.
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Fetoscopic Robotic Open Spina Bifida Treatment [NA]
A fetoscopic robotic surgical treatment trial for open spina bifida is listed as not yet recruiting, sponsored by Mount Sinai Hospital (Cana…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Fetoscopic Neural Tube Defect Repair
This clinical trial update indicates ongoing recruitment for a fetoscopic repair approach to neural tube defects, including spina bifida. Th…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: In-Utero Endoscopic Correction of Spina Bifida [NA]
A clinical trial is recruiting to evaluate in-utero endoscopic correction of spina bifida as a prenatal intervention for neural tube defects…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study [NA]
A pilot study evaluating minimally invasive fetoscopic regenerative repair for spina bifida with myelomeningocele has completed and posted r…
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CLINICAL_TRIALS research · 2017-10-20Clinical Trial Update: Fetal Endoscopic Surgery for Spina Bifida [NA]
Clinical trial update on fetal endoscopic surgery for spina bifida; the current trial status is unknown, with related conditions including n…
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CLINICAL_TRIALS research · 2017-06-26Clinical Trial Update: Powder Topical Rifampicin on Reducing Infections After Neural Tube Defect Surgery in Infants
A clinical trial is evaluating whether powder topical rifampicin reduces postoperative infections after neural tube defect surgery in infant…
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CLINICAL_TRIALS withdrawal · 2016-09-20Clinical Trial Update: A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives [Phase 3]
Phase 3 trial evaluating folate levels in women taking oral contraceptives has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-10-21Clinical Trial Update: Folate Metabolism in Normal Weight and Obese Women of Child-bearing Age
A completed clinical trial compared folate metabolism in normal-weight versus obese women of child-bearing age to inform neural tube defect …
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study) [Phase 1]
Phase 1 study evaluating whether adding inositol to folic acid can prevent neural tube defects in individuals with a history of the conditio…
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FDA approval · 2014-01-27FDA Approved: FOLIC ACID — Original Application (Cadila Pharmaceuticals Limited)
FDA approved Cadila Pharmaceuticals Limited's original application for folic acid (generic), authorizing its marketing in the United States.
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FDA approval · 2013-07-12FDA Approved: FOLIC ACID — Original Application (QUAGEN PHARMACEUTICALS LLC)
The FDA approved an original application for a folic acid product by Quagen Pharmaceuticals LLC, establishing a generic folic acid option.
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Efficacy of Weekly Versus Daily Folic Acid Supplementation [NA]
The study evaluated weekly versus daily folic acid supplementation and reported on its efficacy for neural tube defects.
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Efficacy and Safety Study for an Oral Contraceptive Containing Folate [Phase 3]
Phase 3 trial evaluating efficacy and safety of a folate-containing oral contraceptive has completed and results were posted in 2011.
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CLINICAL_TRIALS research · 2010-12-03Clinical Trial Update: Genetics of Neural Tube Defects
An update on a genetics-focused clinical trial investigating neural tube defects. The trial is sponsored by the John P. Hussman Institute fo…
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FDA approval · 2009-06-09FDA Approved: FOLIC ACID — Original Application (Chartwell RX, LLC.)
FDA approved folic acid under an original application (ANDA 090035) from Chartwell RX, LLC. The entry confirms the product is approved for m…
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CLINICAL_TRIALS trial_result · 2006-07-13Clinical Trial Update: Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification [NA]
A completed CDC-sponsored clinical trial evaluated how different daily dosing schedules of folic acid influence blood folate and homocystein…