Netherton Syndrome
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CLINICAL_TRIALS trial_result · 2026-06-24Clinical Trial Results: Natural History of Netherton Syndrome
Clinical trial results exploring the natural history of Netherton Syndrome, sponsored by Boehringer Ingelheim, has terminated with results p…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome [Phase 2, Phase 3]
Clinical trial update indicating that QRX003 Lotion is being studied in Phase 2/3 for Netherton Syndrome and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Clinical Trial Using Humira in Netherton Syndrome [Phase 2]
This update covers a Phase 2 trial evaluating adalimumab (Humira) for Netherton syndrome, which has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725 [Phase 1]
A Phase 1 clinical trial assessing safety, tolerability, pharmacokinetics, and immunogenicity of BCX17725 in Netherton Syndrome. The study i…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome [Phase 2, Phase 3]
Clinical trial update for QRX003 Lotion in Netherton Syndrome (Phase 2/Phase 3) focusing on safety, tolerability, and efficacy; the study is…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome [Phase 2, Phase 3]
A Boehringer Ingelheim trial evaluating Spesolimab for Netherton Syndrome in Phase 2/Phase 3 has been terminated, with results posted.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome [Phase 1]
An early-stage Phase 1 clinical trial evaluating topical ATR12-351 for adults with Netherton Syndrome, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study of Skin and Gut Microbiome in a Skin Condition Involving Skin Barrier Impairment and Allergic Symptoms: Netherton Syndrome
This clinical trial update outlines a study investigating the skin and gut microbiome in Netherton syndrome, a skin barrier disorder with al…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome [Phase 1, Phase 2]
Phase 1/2 study evaluating the topical SXR1096 cream for Netherton syndrome has completed.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Natural History and Biological Study of Netherton Syndrome [NA]
This clinical trial update reports on the natural history and biology study of Netherton Syndrome, completed in France, and including health…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Natural History of Netherton Syndrome
A natural history study of Netherton Syndrome (NCT05902663) sponsored by Boehringer Ingelheim has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Successful Treatment of Netherton Syndrome With Combination of Secukinumab and Dupilumab
A completed clinical study reports successful treatment of Netherton syndrome with a combination of secukinumab and dupilumab.
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome [Phase 2, Phase 3]
A Phase 2/3 clinical trial of QRX003 Lotion for Netherton Syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Defining the Skin and Blood Biomarkers of Ichthyosis
A clinical trial from Northwestern University is enrolling by invitation to define skin and blood biomarkers of ichthyosis, including Nether…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome [Phase 2, Phase 3]
Open-label safety and efficacy study of QRX003 Lotion in Netherton syndrome; Phase 2/Phase 3, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: A Study to Explore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients With Netherton Syndrome [Phase 1, Phase 2]
A Phase 1/2 study of DS-2325a in Netherton syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2023-08-23Clinical Trial Update: A Pilot Study of the Efficacy and Safety of Dupilumab Versus Placebo in Patients With Netherton Syndrome [Phase 2, Phase 3]
A pilot study investigating the efficacy and safety of dupilumab versus placebo in patients with Netherton syndrome (Phase 2/Phase 3).
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: The Efficacy and Safety of Secukinumab in Patients With Ichthyoses [Phase 2]
Phase 2 trial evaluating the efficacy and safety of secukinumab in patients with ichthyoses has completed; results posted in 2021.
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CLINICAL_TRIALS research · 2016-10-19Clinical Trial Update: Gene Therapy for Netherton Syndrome [Phase 1]
Phase 1 clinical trial update describing a gene therapy being investigated for Netherton Syndrome. The sponsor is Great Ormond Street Hospit…
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CLINICAL_TRIALS trial_result · 2014-12-12Clinical Trial Update: Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome [Phase 1, Phase 2]
A phase 1/2 safety study evaluating the use of Elidel (pimecrolimus) 1% cream in Netherton Syndrome has completed with results posted in 201…