Neovascular Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: Evaluation the Pharmacokinetics, Safety, Tolerability of TK001 in Patients With Neovascular Age-related Macular Degeneration [Phase 1]
Phase 1 trial entry evaluating pharmacokinetics, safety, and tolerability of TK001 in patients with neovascular age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2018-02-12Clinical Trial Update: Efficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration) [Phase 4]
Phase 4 trial updating efficacy and safety of ranibizumab 0.5 mg given in two alternative dosing regimens in Chinese patients with neovascul…
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CLINICAL_TRIALS trial_result · 2018-01-08Clinical Trial Update: Dose Ranging Study of Pazopanib to Treat Neovascular Age-Related Macular Degeneration [Phase 2]
Phase 2 dose-ranging study of pazopanib for neovascular age-related macular degeneration has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Functional and Structural Outcomes in Neovascular Age-related Macular Degeneration [Phase 4]
This report summarizes the functional and structural outcomes from a Phase 4 trial examining neovascular age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: A Study to Evaluate Pazopanib Tablets in Patients Who Have Neovascular Age-related Macular Degeneration [Phase 1]
The document reports the completion of a Phase 1 study evaluating pazopanib tablets in patients with neovascular age-related macular degener…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular Degeneration
A completed clinical trial evaluated the effects of aflibercept on human corneal endothelial cells in neovascular age-related macular degene…
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CLINICAL_TRIALS research · 2017-10-04Clinical Trial Update: Impact of Home Monitoring to Decrease the Treatment Burden for Neovascular Age-related Macular Degeneration (AMD) [Phase 4]
A Phase 4 trial evaluating home monitoring to reduce treatment burden in neovascular age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Safety and Pharmacokinetics of RTH258 in Subjects With Age-Related Macular Degeneration [Phase 2]
This Phase 2 trial update summarizes safety and pharmacokinetics data for RTH258 (brolucizumab) in subjects with neovascular age-related mac…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: To Evaluate the Pharmacodynamics, Safety, and Pharmacokinetics of Pazopanib Drops in Adult Subjects With Neovascular AMD [Phase 2]
Phase 2 clinical trial update evaluating the pharmacodynamics, safety, and pharmacokinetics of pazopanib eye drops in adults with neovascula…
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CLINICAL_TRIALS trial_result · 2017-08-21Clinical Trial Update: 12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD) [Phase 2]
Phase 2 clinical trial update for neovascular age-related macular degeneration; the study was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Study in Patients With Neovascular Age Related Macular Degeneration or Macular Edema Secondary To Retinal Vein Occlusion to Evaluate Usability of the Ranibizumab (Lucentis®) Prefilled Syringe (PFS) [Phase 3]
Phase 3 trial update evaluating the usability of ranibizumab prefilled syringe in patients with neovascular AMD or macular edema due to reti…
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CLINICAL_TRIALS withdrawal · 2017-07-26Clinical Trial Update: Adjunctive Photodynamic Therapy + Aflibercept vs. Afilbercept Alone for PDA in NV AMD [NA]
A clinical trial investigating adjunctive photodynamic therapy with aflibercept for neovascular age-related macular degeneration has been wi…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: The Evolution of Visual Acuity Measured by Electronic Tablet / Computer of Exudative AMD Patients [NA]
This clinical trial update examines changes in visual acuity over time in patients with exudative age-related macular degeneration, measured…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Efficacy and Safety Study of Squalamine Ophthalmic Solution in Subjects With Neovascular AMD [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of Squalamine ophthalmic solution in neovascular age-related macular degeneration.…
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CLINICAL_TRIALS withdrawal · 2017-04-27Clinical Trial Update: Effect of Squalamine Lactate Ophthalmic Solution, 0.2% in Subjects With Neovascular Age-Related Macular Degeneration [Phase 2]
Phase 2 trial of squalamine lactate ophthalmic solution (0.2%) for neovascular age-related macular degeneration has been withdrawn.
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular Degeneration [NA]
Clinical trial update evaluating visual function and driving ability using Ocusweep in patients with wet age-related macular degeneration.
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CLINICAL_TRIALS research · 2017-03-01Clinical Trial Update: Observation of Treatment Patterns With Lucentis in Approved Indications
An observational study examining how Lucentis is used in approved indications such as neovascular age-related macular degeneration and diabe…
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FDA approval · 2017-01-05FDA Approved: LUCENTIS — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for LUCENTIS (ranibizumab) from Genentech, Inc., modifying the existing approval.
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CLINICAL_TRIALS trial_result · 2017-01-02Clinical Trial Update: Efficacy and Safety of Two Treatment Regimens of 0.5 mg Ranibizumab Intravitreal Injections Guided by Functional and/or Anatomical Criteria, in Patients With Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 trial evaluating two dosing regimens of 0.5 mg ranibizumab injections for neovascular age-related macular degeneration reported effi…
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CLINICAL_TRIALS trial_result · 2016-11-21Clinical Trial Update: Assessment of Early Changes in SD-OCT After Initiation of a Treatment by Intravitreal Aflibercept (EYLEA®)START [Phase 4]
This clinical trial update reports completion of a Phase 4 study evaluating early SD-OCT changes after starting intravitreal aflibercept (EY…
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CLINICAL_TRIALS trial_result · 2016-11-04Clinical Trial Update: Safety and Efficacy of Two Regimens of Ranibizumab 0.5 mg in Chinese Patients With Neovascular AMD [Phase 4]
Phase 4 clinical trial evaluating the safety and efficacy of two regimens of intravitreal ranibizumab 0.5 mg in Chinese patients with neovas…
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degeneration [Phase 2]
A Phase 2 trial evaluating regorafenib eye drops for neovascular age-related macular degeneration was terminated, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Observational Study to Evaluate and Compare the Rate and Extent of Inflammation After a Single Intravitreal Injection of Ranibizumab vs. a Single Intravitreal Injection of Aflibercept in Treatment Naive and Treatment Experienced Patients.
This clinical trial update describes the completion of an observational study comparing the rate and extent of intraocular inflammation afte…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: Combination of Ranibizumab and Verteporfin Therapy in Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 clinical trial update on a combination of ranibizumab and verteporfin for neovascular age-related macular degeneration; the study st…
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CLINICAL_TRIALS withdrawal · 2016-03-31Clinical Trial Update: Evaluation the Pharmacokinetics, Safety, Tolerability of BCD-021 in Patients With Neovascular Age-related Macular Degeneration [Phase 1]
A Phase 1 trial evaluating pharmacokinetics, safety, and tolerability of BCD-021 in patients with neovascular age-related macular degenerati…