Neovascular Age-related Macular Degeneration
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular Degeneration [Phase 1, Phase 2]
Phase 1/2 trial update on safety and bioactivity of AXT107 in neovascular age-related macular degeneration; study terminated with posted res…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: Extension Study to Evaluate the Long-term Outcomes of Subjects in the CLS-AX CLS1002-101 Study
An extension study update assessing long-term outcomes from the CLS-AX CLS1002-101 trial in patients with neovascular age-related macular de…
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: A Study to Compare SB15 (Proposed Aflibercept Biosimilar) to Eylea in Subjects With Neovascular Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 trial comparing SB15, a proposed aflibercept biosimilar, to Eylea in neovascular age-related macular degeneration has completed with…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: A Study of EXG102-031 in Participants With wAMD [Phase 1, Phase 2]
A study update for EXG102-031 investigating its safety and efficacy in neovascular age-related macular degeneration across Phase 1 and Phase…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD] [Phase 3]
Phase 3 study comparing ABP 938 to Aflibercept (Eylea) in neovascular (wet) age-related macular degeneration has completed with results post…
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: A Study to Comparing SCD411 and Eylea® in Subjects With Wet Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 trial comparing SCD411 to Eylea in wet/ neovascular age-related macular degeneration has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: A Study in Patients With Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema to Evaluate the Safety of the Faricimab Prefilled Syringe [Phase 3]
Phase 3 trial update assessing the safety of the faricimab prefilled syringe in patients with neovascular age-related macular degeneration o…
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CLINICAL_TRIALS trial_result · 2023-09-06Clinical Trial Update: Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye [Phase 3]
A Phase 3 study evaluating high-dose aflibercept injected into the eye for neovascular age-related macular degeneration has completed, with …
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and tolerability of suprachoroidal CLS-AX injection after anti-VEGF therapy in neovascular age-related mac…
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration [Phase 2]
Phase 2 clinical trial updating safety, tolerability, and efficacy of aflibercept for neovascular age-related macular degeneration has compl…
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CLINICAL_TRIALS trial_result · 2023-05-16Clinical Trial Update: Safety and Tolerability of RGX-314 (Investigational Product) Gene Therapy for Neovascular AMD Trial [Phase 1, Phase 2]
A phase 1/2 trial update reports safety and tolerability findings for RGX-314 gene therapy in neovascular age-related macular degeneration, …
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit [Phase 3]
Phase 3 trial update evaluating the safety of intravitreal SOK583A1 in a vial kit for neovascular age-related macular degeneration has compl…
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: A Randomized, Double-masked, Multicenter,Sham-controlled, Safety and Efficacy Study of KH902 in Patients With Wet AMD [Phase 3]
A Phase 3 randomized, double-masked trial evaluating KH902 for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: Safety Study of Zimura in Combination With Anti-VEGF Therapy in Patients With Neovascular AMD [Phase 2]
A Phase 2 safety study evaluating Zimura in combination with anti-VEGF therapy for neovascular age-related macular degeneration was terminat…
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CLINICAL_TRIALS trial_result · 2023-02-22Clinical Trial Update: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections [Phase 4]
Phase 4 trial update on DEXTENZA for pain and inflammation in patients receiving intravitreal anti-VEGF injections; study terminated.
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CLINICAL_TRIALS trial_result · 2023-02-14Clinical Trial Update: Efficacy and Safety of Aflibercept in Patients With Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 trial update on aflibercept for neovascular age-related macular degeneration assessing efficacy and safety.
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CLINICAL_TRIALS trial_result · 2022-11-18Clinical Trial Update: Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled Syringe [Phase 3]
Phase 3 trial assessing safety of intravitreal SOK583A1 in a prefilled syringe for neovascular age-related macular degeneration (nAMD) compl…
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CLINICAL_TRIALS trial_result · 2022-10-31Clinical Trial Update: A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration [Phase 2]
Phase 2 trial of multiple-dose intravitreal GEM103 for neovascular age-related macular degeneration was terminated, with results posted in 2…
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CLINICAL_TRIALS trial_result · 2022-10-26Clinical Trial Update: A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMD [Phase 2]
Phase 2 trial evaluating AKST4290 in combination with aflibercept for neovascular age-related macular degeneration has completed with result…
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CLINICAL_TRIALS trial_result · 2022-05-04Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (TENAYA) [Phase 3]
The TENAYA Phase 3 trial evaluating faricimab for neovascular age-related macular degeneration has completed and posted results in 2022, rep…
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CLINICAL_TRIALS trial_result · 2022-05-04Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE) [Phase 3]
Phase 3 LUCERNE trial evaluated the efficacy and safety of Faricimab in neovascular age-related macular degeneration; results were posted in…
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CLINICAL_TRIALS trial_result · 2022-04-19Clinical Trial Update: SD-OCT Angiography [NA]
Clinical trial update for SD-OCT Angiography study (NCT02510885) sponsored by Duke University; the trial is terminated, with results posted …
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CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration [Phase 3]
Phase III study evaluating the Port Delivery System with ranibizumab versus monthly injections for wet age-related macular degeneration has …
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CLINICAL_TRIALS trial_result · 2022-02-02Clinical Trial Update: ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD) [Phase 2]
Phase 2 trial evaluating ZIMURA in combination with LUCENTIS for neovascular age-related macular degeneration has completed, with results po…
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMD [Phase 2]
Phase 2 trial comparing a depot formulation of sunitinib malate (GB-102) versus aflibercept in neovascular AMD has completed with posted res…