Necrotizing Enterocolitis
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: WithHolding Enteral Feeds Around Blood Transfusion (International) [NA]
An international trial recruiting to evaluate withholding enteral feeds around blood transfusion in necrotizing enterocolitis.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Multidimensional Dynamic Early Warning System for Neonatal Necrotizing Enterocolitis: A Multicenter Clinical Study
This clinical trial update describes a multicenter study developing a multidimensional dynamic early warning system to detect and prevent ne…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital
A clinical trial update from Assiut University Children's Hospital outlines the pattern and outcomes of neonatal gastrointestinal emergencie…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the safety, tolerability, and preliminary efficacy of ST266 in infants wit…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Predictive Diagnosis of Ulcero-Necrotizing EnteroColitis in Premature Babies Using an Artificial Intelligence Approach Based on Early Analysis of the Fecal Microbiota [NA]
This clinical trial from University Hospital Clermont-Ferrand aims to predict necrotizing enterocolitis in premature infants using an AI ana…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Cohort Study of the Intestinal Microbiota of Premature Infants
This clinical trial update reports a cohort study examining the intestinal microbiota of premature infants, including conditions such as nec…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Mechanisms Affecting the Gut of Preterm Infants Receiving Blood Transfusion With Different Enteral Feed Interventions
A clinical trial evaluating how different enteral feeding strategies influence gut outcomes in preterm infants receiving blood transfusions,…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Health-Related Quality-of-Life and Household Financial and Wellbeing Impacts of Prematurity and Necrotising Enterocolitis (NEC).
ClinicalTrials.gov update on a study sponsored by Imperial College London to assess health-related quality of life, household financial, and…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Normal Intestinal Development and Disease in Premature and Term Neonates
A clinical study exploring normal intestinal development and disease in premature and term neonates, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Long-term Nutritional Impact of Necrotizing Enterocolitis in Premature Newborns.
This clinical trial update indicates that enrollment is ongoing by invitation for a study examining the long-term nutritional impact of necr…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Effects of Enteral Feeding Regimens on NEC, Mortality, and Neurodevelopment in Very Preterm Infants [NA]
The document describes a planned clinical trial evaluating whether different enteral feeding regimens influence necrotizing enterocolitis, m…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality
A clinical trial registered study characterizing extracellular vesicles from cord blood of extremely preterm newborns and examining their as…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: RBC Irradiation, Anemia and Gut Injury
Emory University is conducting a clinical study on red blood cell irradiation for anemia and gut injury, with the trial currently active but…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: RIC-NEC Randomized Controlled Trial [Phase 2]
Phase 2 randomized controlled trial named RIC-NEC for necrotizing enterocolitis; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: NETs: Protection or Harm in Neonatal Inflammation or Infection
Ongoing recruitment for a study evaluating the role of neutrophil extracellular traps (NETs) in neonatal inflammation or infection. The focu…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Assessing the Efficacy of Probiotics in Prevention of NEC in Preterm Babies [NA]
This clinical trial update describes a study evaluating whether probiotic therapy can prevent necrotizing enterocolitis in preterm infants; …
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Sensing Oxygen Saturations Using Abdominal NIRS With an Investigational Realtime Device (Songbird) [NA]
A clinical trial evaluating abdominal near-infrared spectroscopy with an investigational realtime device (Songbird) to monitor oxygen satura…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial [Phase 4]
An open randomized Phase 4 trial compares early hydrocortisone treatment to standard care for shock in extremely preterm neonates.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Amniotic Fluid & the Preterm Gut
Recruitment is ongoing for a study examining amniotic fluid and the preterm gut. The study targets several associated neonatal conditions, i…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: The Correlation Between Red Cell Transfusion and Complications of Prematurity
This clinical trial examines whether red blood cell transfusions are associated with complications of prematurity, including retinopathy of …
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Early Predictors of Necrotizing Enterocolitis in Neonates
A clinical trial at Nationwide Children's Hospital is investigating early predictors of necrotizing enterocolitis in neonates, with recruitm…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Genome-Wide Association Study for Neonatal Diseases
This clinical trial update reports a genome-wide association study investigating neonatal diseases, including necrotizing enterocolitis, whi…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Application of Transcriptome Sequencing Combined With Family-Based Whole Genome Sequencing in Improving Precise Diagnosis of Critically Ill Newborns in Northeast China
This clinical trial investigates using transcriptome sequencing combined with family-based whole genome sequencing to improve precise diagno…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: The Intestinal Innate Immune System in Newborns. Development and Inflammation in Health and Disease
An ongoing clinical study evaluating how the intestinal innate immune system develops in newborns and how inflammation relates to health and…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Do Probiotics Reduce The Risk Of Severe Necrotising Enterocolitis (NEC) In Infants Born Before 32 Weeks Gestation?
An Imperial College London trial is evaluating whether probiotic therapy can reduce the risk of severe necrotizing enterocolitis in infants …