Nasal Polyps
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-13EMA Authorised: Exdensur (depemokimab) — GlaxoSmithKline Trading Services Limited
EMA authorised Exdensur (depemokimab) for asthma and nasal polyps under GlaxoSmithKline Trading Services Limited.
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EMA approval · 2026-03-12EMA Authorised: Exdensur (depemokimab) — GlaxoSmithKline Trading Services Limited
The EMA authorised Exdensur (depemokimab) for treatment indications in asthma and nasal polyps. Decision date 12 February 2026.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Pilot Study of The EPIC Trial [NA]
This is a clinical trial update for the EPIC Trial (NCT02533206) sponsored by the Ottawa Hospital Research Institute. The study is currently…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Complete Remission After Treatment With Biologics for Nasal Polyps [Phase 4]
Phase 4 clinical trial evaluating biologics for nasal polyps reports complete remission in treated participants.
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps [NA]
A clinical trial evaluating a surgical approach described as Full-House ESS with nasopharyngeal lymphoid tissue ablation for nasal polyps is…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease [Phase 2]
Phase 2 trial evaluating the benefits of IL-4 receptor alpha inhibition for aspirin-exacerbated respiratory disease, including asthma and na…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps [NA]
Clinical trial update on a Medical University of Vienna study exploring precision medicine in United Airways Disease, examining inflammatory…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Dupixent Study for Alternate Administration [Phase 4]
Phase 4 study evaluating alternate administration of dupilumab (Dupixent) for nasal polyps and sinusitis; the trial is currently active but …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218) [Phase 3]
A Phase 3 clinical trial (NCT00731185, study P03218) evaluating mometasone furoate nasal spray for the treatment of nasal polyps after surge…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Preclinical Studies of Omalizumab in Chronic Rhinosinusitis With Nasal Polyposis [EARLY_Phase 1]
This update summarizes early-phase studies of omalizumab for chronic rhinosinusitis with nasal polyps, with the trial status listed as compl…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray [Phase 3]
A Phase 3 trial evaluating dupilumab for Allergic Fungal Rhinosinusitis after endoscopic sinus surgery has been withdrawn.
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: BIOlogics in Severe Nasal POlyposis SurvEy.: a French Registry [NA]
Registry entry for a French survey on biologics in severe nasal polyposis; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide [Phase 2]
Phase 2 clinical trial on topical furosemide for post-operative nasal polyps was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposis [Phase 2, Phase 3]
A clinical trial update indicates an adjunctive treatment being studied for chronic rhinosinusitis with nasal polyposis across Phase 2 and P…
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CLINICAL_TRIALS trial_result · 2023-07-14Clinical Trial Update: Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban [Phase 2]
Phase 2 trial investigating Ifetroban for aspirin-exacerbated respiratory disease (AERD) shows completed status with results posted.
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FDA approval · 2023-03-09FDA Approved: RUGBY MOMETASONE FUROATE NASAL — Supplemental Application (Rugby Laboratories)
FDA approved a supplemental application for Rugby Mometasone Furoate Nasal (mometasone furoate) submitted by Rugby Laboratories.
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: The Role of Budesonide Intrapolyp Injection in CRSwNP [Phase 4]
Phase 4 trial update investigating budesonide intrapolyp injection for chronic rhinosinusitis with nasal polyps (CRSwNP).
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1) [Phase 2]
Phase 2 trial of subcutaneously administered CM310 versus placebo in chronic rhinosinusitis with nasal polyposis has completed.
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: Omalizumab Efficacy in Patients With Refractory Nasal Polyps [Phase 4]
Phase 4 trial update evaluating the efficacy of omalizumab in patients with refractory nasal polyps.
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CLINICAL_TRIALS trial_result · 2022-05-25Clinical Trial Update: Anti-Inflammatory Agent in Sinusitis [Phase 2]
Phase 2 trial results for an anti-inflammatory agent in nasal polyps (sinusitis) have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-11-05Clinical Trial Update: Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis [Phase 2]
Phase 2 trial investigating botulinum toxin type A block of the sphenopalatine ganglion for chronic rhinosinusitis with nasal polyposis has …
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis [Phase 2]
Phase 2 trial updating benralizumab’s effect on severe chronic rhinosinusitis with eosinophilic polyposis; study completed with results post…
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery [Phase 4]
Phase 4 trial comparing topical oxymetazoline versus epinephrine as preoperative vasoconstrictors for endoscopic sinus surgery; results post…
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma [Phase 3]
Phase 3 trial update on the efficacy of fevipiprant in nasal polyposis; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Effect of Mepolizumab in Severe Bilateral Nasal Polyps [Phase 3]
Phase 3 trial update on mepolizumab for severe bilateral nasal polyps; results posted after completion.